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The map label for this gene is fur [H]

Identifier: 49186999

GI number: 49186999

Start: 3940692

End: 3941147

Strand: Reverse

Name: fur [H]

Synonym: BAS4001

Alternate gene names: 49186999

Gene position: 3941147-3940692 (Counterclockwise)

Preceding gene: 49187000

Following gene: 49186998

Centisome position: 75.38

GC content: 38.38

Gene sequence:

>456_bases
ATGGAAGAAAGAATTGAACGAATTAAGAAGCAATTACATGCAGCGAGCTACAAATTAACACCGCAACGTGAAGCAACAGT
TCGTGTGCTGCTAGAAAATGAAGAAGATCATTTAAGCGCAGAAGATGTTTACCTCCTTGTAAAAGAAAAGTCGCCAGAGA
TCGGATTAGCAACCGTCTATCGAACTTTAGAACTATTATCTGAGTTAAAAGTTGTCGATAAGATTAACTTCGGAGACGGT
GTTTCACGCTATGACTTACGCCAAGAAGGTGCGCAGCGTTTCCACCATCATTTGATTTGTACACAATGTGGTGCTGTACA
AGAAATACAAGAAGATTTACTTGGTGAAGTGGAAAGGAAAGTAGAACATGACTGGAGCTTTAAGGTGAAGGATCATCGTT
TAACATTCCATGGGATTTGTAAAAATTGTCAAGAAAATGAAACGGATGAAAAATAA

Upstream 100 bases:

>100_bases
TATGAGAATAATTATCAATTTGTTTTTATTGTTTTTCTTTTGACAGAAGCCCTTCTTCTGATATAATGGTGTAAGAGTGG
CGAGGAGGGAGTAGTACCGA

Downstream 100 bases:

>100_bases
CCTTTTCCTATTTAACTAGGAAGAGGTTTTTTATTTGAATAAGGTATAAATTGGTGAAAGCTTGGCATATGTTGTAATAA
CTTATATTTTGGAGGAATTT

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MEERIERIKKQLHAASYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLSELKVVDKINFGDG
VSRYDLRQEGAQRFHHHLICTQCGAVQEIQEDLLGEVERKVEHDWSFKVKDHRLTFHGICKNCQENETDEK

Sequences:

>Translated_151_residues
MEERIERIKKQLHAASYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLSELKVVDKINFGDG
VSRYDLRQEGAQRFHHHLICTQCGAVQEIQEDLLGEVERKVEHDWSFKVKDHRLTFHGICKNCQENETDEK
>Mature_151_residues
MEERIERIKKQLHAASYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLSELKVVDKINFGDG
VSRYDLRQEGAQRFHHHLICTQCGAVQEIQEDLLGEVERKVEHDWSFKVKDHRLTFHGICKNCQENETDEK

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=138, Percent_Identity=36.231884057971, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17642; Mature: 17642

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERIERIKKQLHAASYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVY
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLSELKVVDKINFGDGVSRYDLRQEGAQRFHHHLICTQCGAVQEIQEDLLGEVERK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VEHDWSFKVKDHRLTFHGICKNCQENETDEK
HCCCCCEEEECCEEHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEERIERIKKQLHAASYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVY
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHH
RTLELLSELKVVDKINFGDGVSRYDLRQEGAQRFHHHLICTQCGAVQEIQEDLLGEVERK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VEHDWSFKVKDHRLTFHGICKNCQENETDEK
HCCCCCEEEECCEEHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]