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The map label for this gene is xerD [H]

Identifier: 49186997

GI number: 49186997

Start: 3939461

End: 3940351

Strand: Reverse

Name: xerD [H]

Synonym: BAS3999

Alternate gene names: 49186997

Gene position: 3940351-3939461 (Counterclockwise)

Preceding gene: 49186998

Following gene: 49186996

Centisome position: 75.36

GC content: 36.48

Gene sequence:

>891_bases
TTGGAAGATCAATTAAAAGATTTTATTCATTATATGGTTGTGGAAAAAGGGCTAGCGAAAAATACAGTAGTATCTTATGA
ACGTGATTTGAAAAGTTATGTAAAGTATTTGCAAAAGGTAGAACAAGCGAAAAGCTTTCACGAAGTGACACGCTTGCACA
TTGTTAATTTTCTGCAGCACTTAAAAGAAAACGGAAAATCTTCGAAAACATTAGCACGTCATATTGCATCGATTCGTTCG
TTTCATCAATTTTTACTTCGTGAACGAGCAGTAGAGCACGATCCATCCGTACATATTGAAACGCCGCAAGGAGAACGGAA
ATTACCGAAAGTATTGTCAGTTGATGAAGTAGAGGCGTTACTTCAGACACCAAAAATGACGAGTGCTTTTGGGGTTCGTG
ATAAAGCGATGCTAGAGTTACTGTATGCAACAGGACTTCGTGTTTCAGAATTAATTGCCTTAAATTTAGAAGATGTACAT
TTAACGATGGGATTTGTTCGTTGCGTAGGGAAAGGGAATAAAGAAAGAATTATTCCACTAGGAAGCTTAGCGACGGAAGC
GATTCAAAAGTATATTGAAAAGGGAAGAAGAGAATTGATGGGAAAAAAAGTAGTAGATGCACTCTTTTTAAACCATCATG
GAAATCGATTATCAAGACAAGGATTTTGGAAGATTTTAAAACGATTAGCGAAAGAAGCAAATATTGAAAAAGAGCTTACA
CCTCATACGTTGCGCCATTCTTTTGCAACGCATTTATTAGAAAATGGAGCAGACTTGCGTGCTGTGCAAGAAATGCTTGG
GCATGCAGATATTTCAACGACACAAATTTATACGCATGTTTCAAAAACTAGATTAAAAGATGTATATAAACAGTTTCATC
CGAGAGCATAG

Upstream 100 bases:

>100_bases
AGAAGAGACTGTAGAAAAAGTATCAGGGAATGAAGAGCCGGCAAAGGATGCTTTCGTAAATAGAATGATGTTTTTCTATG
AAAATGGGGAGTAGTGTAGA

Downstream 100 bases:

>100_bases
TTACTATGCTCTTTTTTCATAGATTCAAAAGGCTATAATACTTCACAGAAACTTCACAAACATTTCGTACATTGTTTTCA
GCAGAAGACTAGAATATTAC

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQAKSFHEVTRLHIVNFLQHLKENGKSSKTLARHIASIRS
FHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVDEVEALLQTPKMTSAFGVRDKAMLELLYATGLRVSELIALNLEDVH
LTMGFVRCVGKGNKERIIPLGSLATEAIQKYIEKGRRELMGKKVVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA

Sequences:

>Translated_296_residues
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQAKSFHEVTRLHIVNFLQHLKENGKSSKTLARHIASIRS
FHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVDEVEALLQTPKMTSAFGVRDKAMLELLYATGLRVSELIALNLEDVH
LTMGFVRCVGKGNKERIIPLGSLATEAIQKYIEKGRRELMGKKVVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA
>Mature_296_residues
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQAKSFHEVTRLHIVNFLQHLKENGKSSKTLARHIASIRS
FHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVDEVEALLQTPKMTSAFGVRDKAMLELLYATGLRVSELIALNLEDVH
LTMGFVRCVGKGNKERIIPLGSLATEAIQKYIEKGRRELMGKKVVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=44.5578231292517, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI1790244, Length=289, Percent_Identity=36.3321799307958, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1790768, Length=183, Percent_Identity=32.2404371584699, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790767, Length=193, Percent_Identity=27.4611398963731, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34015; Mature: 34015

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQAKSFHEVTRLHIVNFLQH
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKENGKSSKTLARHIASIRSFHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVDEVEAL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCHHHHHHH
LQTPKMTSAFGVRDKAMLELLYATGLRVSELIALNLEDVHLTMGFVRCVGKGNKERIIPL
HHCCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEH
GSLATEAIQKYIEKGRRELMGKKVVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQAKSFHEVTRLHIVNFLQH
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKENGKSSKTLARHIASIRSFHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVDEVEAL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHCHHHHHHH
LQTPKMTSAFGVRDKAMLELLYATGLRVSELIALNLEDVHLTMGFVRCVGKGNKERIIPL
HHCCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEH
GSLATEAIQKYIEKGRRELMGKKVVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]