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The map label for this gene is nagB

Identifier: 49186962

GI number: 49186962

Start: 3909367

End: 3910155

Strand: Reverse

Name: nagB

Synonym: BAS3964

Alternate gene names: 49186962

Gene position: 3910155-3909367 (Counterclockwise)

Preceding gene: 49186963

Following gene: 49186961

Centisome position: 74.78

GC content: 37.77

Gene sequence:

>789_bases
ATGAATATTCTTGTTGTAAAAACTCCAGAAGAACTAGCAGAAGCAGGTTATAAATTAATTGAAGAAGTTGTAAAAACAAA
AGAAAATCCAACATTAGGAATGGCTACAGGAAGCTCTCCATTAGGTATTTATGCAGAAATGCGAAAAAATAAACTTGATA
CAAGCCGTGTAACCACTGTAAACTTAGATGAGTACGTAAATTTACCACATGAAGATAAAAACAGCTATCATTATTTCATG
CAAGAACAGTTGTTTGATCATCTTCCATTTAAACAAACTTATGTACCAAACGGGATGGCAAGTGATTTAGAGGAAGAGTG
CAAACGTTACGAGGGCATTCTAGCTGCTAACCCAGTTGACCTACAGATTCTTGGAATCGGTGAAAACGGTCACATCGGAT
TTAACGAGCCAGGAACACCGTTTAATTCTCCAACCAACATTGTTGAATTAACAGAATCTACACGCCAAGCAAACCTTCGC
TTCTTCGAAAAAGAAGAAGATGTGCCAACTCATGCAATTACAATGGGAATTGGAAGCATTATGAAAGCGAAACAAATTCT
ACTTGTTGCTATGGGTTCTAAAAAGGCAGAAGCTGTTAAAGAATTATTGCAAGGTGCATATAGTGAAGCGTGTCCTGCTA
CAGTTTTACAACGTCATCCGAATGTAACCGTAATCGCTGATCAAGAAGCTCTATCTTTATGCAGTGAGGCGATTGCTGAT
GAACATCGACAAGTATTCACCATTTCCGATCTATTATCAGATTCAAGAGTGGGTGAAACAGCTAATTGA

Upstream 100 bases:

>100_bases
GCGGTAGGAAAAGATGCAGACTTTGTTGTGATGAATGAAGATTTACATGTATATGATACGGTTCGTTTAGGAATTCATAT
GAAGGAAGGGAAGTAATTAA

Downstream 100 bases:

>100_bases
GGACGGCGAATGGAAGCCGGGAGATAAAATCCCATCTGAGAATGAACTTTGCGATAAGTTCGAAGTGAGTCGTATGACAA
TCAGACAGGCGATTAATAAT

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFM
QEQLFDHLPFKQTYVPNGMASDLEEECKRYEGILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLR
FFEKEEDVPTHAITMGIGSIMKAKQILLVAMGSKKAEAVKELLQGAYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
EHRQVFTISDLLSDSRVGETAN

Sequences:

>Translated_262_residues
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFM
QEQLFDHLPFKQTYVPNGMASDLEEECKRYEGILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLR
FFEKEEDVPTHAITMGIGSIMKAKQILLVAMGSKKAEAVKELLQGAYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
EHRQVFTISDLLSDSRVGETAN
>Mature_262_residues
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFM
QEQLFDHLPFKQTYVPNGMASDLEEECKRYEGILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLR
FFEKEEDVPTHAITMGIGSIMKAKQILLVAMGSKKAEAVKELLQGAYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
EHRQVFTISDLLSDSRVGETAN

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily

Homologues:

Organism=Homo sapiens, GI13027378, Length=243, Percent_Identity=34.156378600823, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI19923881, Length=208, Percent_Identity=35.0961538461538, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1786893, Length=241, Percent_Identity=34.0248962655602, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1789530, Length=223, Percent_Identity=30.0448430493274, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI48994958, Length=240, Percent_Identity=27.5, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554876, Length=242, Percent_Identity=35.9504132231405, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24581960, Length=243, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI19920764, Length=243, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGB_BACAA (C3P761)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868354.1
- ProteinModelPortal:   C3P761
- SMR:   C3P761
- EnsemblBacteria:   EBBACT00000129850
- GeneID:   7849621
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4296
- GeneTree:   EBGT00050000002591
- ProtClustDB:   PRK00443
- HAMAP:   MF_01241
- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321
- PANTHER:   PTHR11280
- TIGRFAMs:   TIGR00502

Pfam domain/function: PF01182 Glucosamine_iso

EC number: =3.5.99.6

Molecular weight: Translated: 28971; Mature: 28971

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: ACT_SITE 63-63 ACT_SITE 129-129 ACT_SITE 131-131 ACT_SITE 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTV
CCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCHHEEEE
NLDEYVNLPHEDKNSYHYFMQEQLFDHLPFKQTYVPNGMASDLEEECKRYEGILAANPVD
EHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHCCEEECCCCE
LQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLRFFEKEEDVPTHAITMGIGSI
EEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCEEEECCCCCCHHHHHHHHHHH
MKAKQILLVAMGSKKAEAVKELLQGAYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
HHHHHEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHH
EHRQVFTISDLLSDSRVGETAN
HHHEEEEHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTV
CCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCHHEEEE
NLDEYVNLPHEDKNSYHYFMQEQLFDHLPFKQTYVPNGMASDLEEECKRYEGILAANPVD
EHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHCCEEECCCCE
LQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLRFFEKEEDVPTHAITMGIGSI
EEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCEEEECCCCCCHHHHHHHHHHH
MKAKQILLVAMGSKKAEAVKELLQGAYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
HHHHHEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHH
EHRQVFTISDLLSDSRVGETAN
HHHEEEEHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA