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The map label for this gene is mtnB

Identifier: 49186946

GI number: 49186946

Start: 3895500

End: 3896138

Strand: Direct

Name: mtnB

Synonym: BAS3948

Alternate gene names: 49186946

Gene position: 3895500-3896138 (Clockwise)

Preceding gene: 49186945

Following gene: 49186947

Centisome position: 74.5

GC content: 36.93

Gene sequence:

>639_bases
ATGAAACAACTTTTTCGTCAATGGTATGACTTAAGCGAGATAAAAAAAGAATTAACAACACGAAATTGGTTTCCAGCAAC
GAGTGGTAATATTTCTATAAAGGTTAGTCATGAACCACTCACTTTTCTCATTACAGCAAGTGGTAAAGATAAAACCAAAA
CGACTCCAGATGACTTTCTACTAGTAGATCATCTAGGGGTTCCCGTATTAGAGACTGAATTACGTCCCTCAGCAGAAACA
ATCTTGCATACACATATTTATAACAATACGAATGCTGGGTGCGTCCTTCATGTTCATACAACTGATAACAATGTGATCAC
AAATTTATATAGTGATGCCGTCACACTTCAAAATCAAGAAATTATTAAAGCTCTCGATATTTGGGAAGAAGGTGCAACAA
TTCACATTCCTATTATCGAAAACCATGCTCATATCCCAACGCTTGGAGAAAACTTCCGCAAGCATATACAGGGAGATTCG
GGGGCAGTATTAATCCGTAACCATGGTATTACCGTATGGGGCCGAGATAGCTTTGATGCAAAGAAAAGATTAGAAGCTTA
TGAGTTTTTATTCCAATTTCATATAAAACTACTATCAATTCAAGGAGGCGTTTCTAATGGCGCAAATTCGTATTCATGA

Upstream 100 bases:

>100_bases
TCCTTATTACAAAATGCGAAGAAAATCATATTTCTTATACACCATTTGAAACGTTTCACGATGTTAAAACTGAATTAAAA
CATTTGTTGGAGGTGAAATT

Downstream 100 bases:

>100_bases
AGTAAATACTCGCATTGAAAATGAAGTGAAAGTATCTAAATTTCTACAAGAGGAAGGTGTTTTATATGAGAAATGGAATA
TTTCTAAACTTCCTCCTCAT

Product: methylthioribulose-1-phosphate dehydratase

Products: NA

Alternate protein names: MTRu-1-P dehydratase

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHLGVPVLETELRPSAET
ILHTHIYNNTNAGCVLHVHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDS
GAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS

Sequences:

>Translated_212_residues
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHLGVPVLETELRPSAET
ILHTHIYNNTNAGCVLHVHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDS
GAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
>Mature_212_residues
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHLGVPVLETELRPSAET
ILHTHIYNNTNAGCVLHVHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDS
GAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily

Homologues:

Organism=Homo sapiens, GI166235186, Length=205, Percent_Identity=28.2926829268293, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322484, Length=208, Percent_Identity=31.25, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18859685, Length=209, Percent_Identity=27.7511961722488, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNB_BACAA (C3P747)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868340.1
- ProteinModelPortal:   C3P747
- SMR:   C3P747
- EnsemblBacteria:   EBBACT00000129807
- GeneID:   7850858
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4280
- GeneTree:   EBGT00050000002065
- ProtClustDB:   PRK06754
- HAMAP:   MF_01677
- InterPro:   IPR001303
- InterPro:   IPR017714
- Gene3D:   G3DSA:3.40.225.10
- TIGRFAMs:   TIGR03328

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.2.1.109

Molecular weight: Translated: 23911; Mature: 23911

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFL
CHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEE
LVDHLGVPVLETELRPSAETILHTHIYNNTNAGCVLHVHTTDNNVITNLYSDAVTLQNQE
EEECCCCCEEECCCCCCHHHEEEEEEECCCCCCEEEEEEECCCCEEEHHHHCEEEECCHH
IIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDSGAVLIRNHGITVWGRDSFDA
HHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCH
KKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFL
CHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEE
LVDHLGVPVLETELRPSAETILHTHIYNNTNAGCVLHVHTTDNNVITNLYSDAVTLQNQE
EEECCCCCEEECCCCCCHHHEEEEEEECCCCCCEEEEEEECCCCEEEHHHHCEEEECCHH
IIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDSGAVLIRNHGITVWGRDSFDA
HHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCH
KKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA