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The map label for this gene is mtnU [H]

Identifier: 49186942

GI number: 49186942

Start: 3891311

End: 3892090

Strand: Reverse

Name: mtnU [H]

Synonym: BAS3944

Alternate gene names: 49186942

Gene position: 3892090-3891311 (Counterclockwise)

Preceding gene: 49186949

Following gene: 49186941

Centisome position: 74.44

GC content: 35.0

Gene sequence:

>780_bases
ATGAAAGTCGCATGTATTCAAATGGATATTTTCTTTGGAGATGTAGAAAAAAATATTGAGAATGCTAAAAATAAAATAAG
CGAAGCAATGAAGGAAAGACCAGATGTTATCGTCTTACCAGAACTATGGACAACAGGTTATGATTTAACGAGACTTTCTG
AAATTGCAGATAGGGATGGATTGGAAACGAAAGAAAAGTTGATAGAATGGTCGAAACAATATGGTGTACATATTGTTGGT
GGTTCTATAGCAAAGCAAACAGAACAAGGTGTTACAAATACAATGTATGTTGTAACGAATAAAGGAGAACTAGTTAATGA
ATACAGTAAAGTACATTTATTTCAGCTTATGGATGAACATAAATATTTAATCGCTGGAAATAGTACAGGTGAATTTAAGT
TAGATGATGTAGAGTGTGCCGGCACAATTTGTTATGACATTCGTTTTCCAGAGTGGATGCGTGTTCATACTGCTAAAGGT
GCAAAAGTTTTATTTGTTGTAGCTGAATGGCCATTAGTTCGTTTAGCACATTGGCGTTTGCTATTACAAGCAAGAGCGGT
TGAAAATCAGTGTTATGTTGTTGCATGTAATAGGGCAGGAAAAGATCCAAATAATGAGTTTGCTGGTCATTCTTTAATTG
TCGACCCTTGGGGCGAAGTTGTTGTAGAAGCGAATGAAGAAGAATCAATTTTATTTGGAGAGCTTACATTCGAGAAAATT
GAAGAAGTACGTAAAGGAATTCCAGTTTTTGCAGATCGTCGTCCAGAATTATACAAATAA

Upstream 100 bases:

>100_bases
CATACTTTCCACCTCTTTTGAAAGTTGTTACAATTCTAGTGACAAATAATATAATCTTTCCAGTATTTTGTAAAGAAAAA
ATGAGAATGGGGCTGAAAAA

Downstream 100 bases:

>100_bases
AATGTTGACAAGTGATTTTTATTCTTGGTATAGTCTTCAACATAAAGTTAAAAATTCTAAAAAATTATACAACTCTTATC
AAGAGCAGGTGGAGGGATTT

Product: carbon-nitrogen family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVLPELWTTGYDLTRLSEIADRDGLETKEKLIEWSKQYGVHIVG
GSIAKQTEQGVTNTMYVVTNKGELVNEYSKVHLFQLMDEHKYLIAGNSTGEFKLDDVECAGTICYDIRFPEWMRVHTAKG
AKVLFVVAEWPLVRLAHWRLLLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGEVVVEANEEESILFGELTFEKI
EEVRKGIPVFADRRPELYK

Sequences:

>Translated_259_residues
MKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVLPELWTTGYDLTRLSEIADRDGLETKEKLIEWSKQYGVHIVG
GSIAKQTEQGVTNTMYVVTNKGELVNEYSKVHLFQLMDEHKYLIAGNSTGEFKLDDVECAGTICYDIRFPEWMRVHTAKG
AKVLFVVAEWPLVRLAHWRLLLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGEVVVEANEEESILFGELTFEKI
EEVRKGIPVFADRRPELYK
>Mature_259_residues
MKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVLPELWTTGYDLTRLSEIADRDGLETKEKLIEWSKQYGVHIVG
GSIAKQTEQGVTNTMYVVTNKGELVNEYSKVHLFQLMDEHKYLIAGNSTGEFKLDDVECAGTICYDIRFPEWMRVHTAKG
AKVLFVVAEWPLVRLAHWRLLLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGEVVVEANEEESILFGELTFEKI
EEVRKGIPVFADRRPELYK

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=267, Percent_Identity=32.9588014981273, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI297632350, Length=261, Percent_Identity=27.5862068965517, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI5031947, Length=261, Percent_Identity=27.5862068965517, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI297632348, Length=261, Percent_Identity=27.5862068965517, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1786412, Length=258, Percent_Identity=32.5581395348837, Blast_Score=137, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17556280, Length=260, Percent_Identity=32.6923076923077, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323383, Length=276, Percent_Identity=31.8840579710145, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322335, Length=292, Percent_Identity=26.7123287671233, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI21355835, Length=274, Percent_Identity=34.3065693430657, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17933642, Length=257, Percent_Identity=27.2373540856031, Blast_Score=95, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29555; Mature: 29555

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVLPELWTTGYDLTRLSEIADRDG
CEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCC
LETKEKLIEWSKQYGVHIVGGSIAKQTEQGVTNTMYVVTNKGELVNEYSKVHLFQLMDEH
CHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCC
KYLIAGNSTGEFKLDDVECAGTICYDIRFPEWMRVHTAKGAKVLFVVAEWPLVRLAHWRL
EEEEEECCCCCEEECCEEECCEEEEEEECCCCEEEEECCCCEEEEEEECCCHHHHHHHHH
LLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGEVVVEANEEESILFGELTFEKI
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEEECCHHHH
EEVRKGIPVFADRRPELYK
HHHHCCCCEEECCCCCCCC
>Mature Secondary Structure
MKVACIQMDIFFGDVEKNIENAKNKISEAMKERPDVIVLPELWTTGYDLTRLSEIADRDG
CEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCC
LETKEKLIEWSKQYGVHIVGGSIAKQTEQGVTNTMYVVTNKGELVNEYSKVHLFQLMDEH
CHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCC
KYLIAGNSTGEFKLDDVECAGTICYDIRFPEWMRVHTAKGAKVLFVVAEWPLVRLAHWRL
EEEEEECCCCCEEECCEEECCEEEEEEECCCCEEEEECCCCEEEEEEECCCHHHHHHHHH
LLQARAVENQCYVVACNRAGKDPNNEFAGHSLIVDPWGEVVVEANEEESILFGELTFEKI
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEEECCHHHH
EEVRKGIPVFADRRPELYK
HHHHCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]