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The map label for this gene is nucA [H]

Identifier: 49186912

GI number: 49186912

Start: 3862791

End: 3863225

Strand: Reverse

Name: nucA [H]

Synonym: BAS3914

Alternate gene names: 49186912

Gene position: 3863225-3862791 (Counterclockwise)

Preceding gene: 49186914

Following gene: 49186911

Centisome position: 73.89

GC content: 38.85

Gene sequence:

>435_bases
ATGAAGCAATTAAAAGGTATTATCATTTCAATTATTGCAATTCTTTCTATTTTAGTAGCGGTTTATGAAGTACTTGTTCC
AGAGGAAACAAGTACAAAAAAAACAAATGCGTATGATCAAGTTCTAGAATTTCCGAAAGAGAGATATCCAGAAACAGGGA
AACATATTACGGATGCGATAAAGGAAGGACATTCAGAAGTTTGTACAATCGACCGTGGTGGCGCTGCGGATAGAAGAAAG
TTATCGTTAGCTCCATACCCATCAAAAAAAGGGTATGATCGTGATGAATGGCCAATGGCGATGTGTAAAGAAGGCGGAAA
AGGAGCACATATCGAATATATAAGTCCAGCAGATAACCGCGGAGCAGGGTCTTGGGTAGGAAATAAGTTAGATAAATACC
CAGATGGTACGCGTGTGAAATTTGACGTAAAGTAG

Upstream 100 bases:

>100_bases
GAATGGCGAAGAAGAACTAAAATAATGTCTGAAAACATAGACAGGATAAGTTTGTTATAATAACTGAGGAAAAGAAACTG
GTAGAGTCACGGAGGTATAC

Downstream 100 bases:

>100_bases
TAGTTGCATATTTCATAATGAAGGAGGAGGGGAACGATGGAGTTAACAATTTCTTATTCGCAATTAATGTTAATGAACTA
TGATGGTGAGCAGCCTTACG

Product: competence-specific nuclease

Products: NA

Alternate protein names: Competence-specific nuclease [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKQLKGIIISIIAILSILVAVYEVLVPEETSTKKTNAYDQVLEFPKERYPETGKHITDAIKEGHSEVCTIDRGGAADRRK
LSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNRGAGSWVGNKLDKYPDGTRVKFDVK

Sequences:

>Translated_144_residues
MKQLKGIIISIIAILSILVAVYEVLVPEETSTKKTNAYDQVLEFPKERYPETGKHITDAIKEGHSEVCTIDRGGAADRRK
LSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNRGAGSWVGNKLDKYPDGTRVKFDVK
>Mature_144_residues
MKQLKGIIISIIAILSILVAVYEVLVPEETSTKKTNAYDQVLEFPKERYPETGKHITDAIKEGHSEVCTIDRGGAADRRK
LSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNRGAGSWVGNKLDKYPDGTRVKFDVK

Specific function: By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed. Degrades both double- stranded, linear and covalently closed circular DNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis nucB [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 16012; Mature: 16012

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLKGIIISIIAILSILVAVYEVLVPEETSTKKTNAYDQVLEFPKERYPETGKHITDAI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHCCCCCHHHHHHH
KEGHSEVCTIDRGGAADRRKLSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNR
HCCCCCEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCC
GAGSWVGNKLDKYPDGTRVKFDVK
CCCCHHHHHHHCCCCCCEEEEECC
>Mature Secondary Structure
MKQLKGIIISIIAILSILVAVYEVLVPEETSTKKTNAYDQVLEFPKERYPETGKHITDAI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHCCCCCHHHHHHH
KEGHSEVCTIDRGGAADRRKLSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNR
HCCCCCEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCC
GAGSWVGNKLDKYPDGTRVKFDVK
CCCCHHHHHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704255; 7746143; 8969502; 9384377; 2841296 [H]