| Definition | Bacillus anthracis str. Sterne chromosome, complete genome. |
|---|---|
| Accession | NC_005945 |
| Length | 5,228,663 |
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The map label for this gene is fadH [H]
Identifier: 49186898
GI number: 49186898
Start: 3847145
End: 3847909
Strand: Reverse
Name: fadH [H]
Synonym: BAS3900
Alternate gene names: 49186898
Gene position: 3847909-3847145 (Counterclockwise)
Preceding gene: 49186901
Following gene: 49186897
Centisome position: 73.59
GC content: 39.87
Gene sequence:
>765_bases GTGAAAGAAAAGGTAGTTATTATAACAGGTGGATCGAGCGGAATGGGAAAAGGAATGGCAACTCGTTTTGCAAAAGAAGG GGCACGAGTTGTTATTACAGGACGTACAAAGGAAAAATTAGAGGAAGCCAAGTTAGAAATTGAACAATTTCCAGGGCAAA TATTAACTGTACAAATGGATGTGAGAAATACGGATGACATTCAGAAAATGATTGAACAGATTGATGAGAAGTTTGGACGA ATTGATATTTTAATAAATAATGCAGCTGGGAATTTTATTTGTCCAGCAGAAGATTTATCCGTGAACGGGTGGAATTCGGT CATTAATATTGTGTTAAACGGTACATTTTACTGTAGTCAGGCTATCGGAAAATATTGGATTGAAAAAGGTATAAAAGGGA ATATCATTAACATGGTAGCAACATATGCATGGGATGCAGGTCCAGGAGTGATTCATTCGGCTGCAGCGAAGGCTGGAGTA TTAGCAATGACAAAGACACTCGCTGTTGAGTGGGGACGCAAATATGGAATCCGAGTTAACGCGATCGCGCCAGGACCAAT TGAACGTACGGGCGGTGCTGATAAATTATGGATTTCAGAAGAAATGGCCAAGCGCACGATACAAAGTGTTCCGCTTGGAA GGCTAGGTACGCCAGAAGAAATTGCAGGTCTAGCTTATTATTTATGTTCAGATGAAGCTGCGTACATAAATGGAACTTGT ATGACAATGGATGGAGGACAACATTTACATCAATATCCATTTTAA
Upstream 100 bases:
>100_bases CCTCTTTACGTTAAAATATCAGAAAAATTTAAAAATATAAAGATTTCTATTAAATAAAATGATAAAATGAATATGTATTC ATTTTTTGGAGGGGATGTAT
Downstream 100 bases:
>100_bases AAGGGATAAAAAAATGAATGTTTCATTCATTTTTTTACGGTTAAATGTGACGGAATTGTGACATATGAAAGAAAAGTGTT TACAAGAGGTCATATATACG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 254; Mature: 254
Protein sequence:
>254_residues MKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEEAKLEIEQFPGQILTVQMDVRNTDDIQKMIEQIDEKFGR IDILINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYCSQAIGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGV LAMTKTLAVEWGRKYGIRVNAIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYINGTC MTMDGGQHLHQYPF
Sequences:
>Translated_254_residues MKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEEAKLEIEQFPGQILTVQMDVRNTDDIQKMIEQIDEKFGR IDILINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYCSQAIGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGV LAMTKTLAVEWGRKYGIRVNAIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYINGTC MTMDGGQHLHQYPF >Mature_254_residues MKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEEAKLEIEQFPGQILTVQMDVRNTDDIQKMIEQIDEKFGR IDILINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYCSQAIGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGV LAMTKTLAVEWGRKYGIRVNAIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYINGTC MTMDGGQHLHQYPF
Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]
Homologues:
Organism=Homo sapiens, GI4503301, Length=224, Percent_Identity=42.4107142857143, Blast_Score=174, Evalue=6e-44, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=39.9193548387097, Blast_Score=167, Evalue=8e-42, Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=33.206106870229, Blast_Score=166, Evalue=2e-41, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=29.6, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=29.9610894941634, Blast_Score=114, Evalue=6e-26, Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=31.6205533596838, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI59889578, Length=240, Percent_Identity=32.5, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=29.9595141700405, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=25.7261410788382, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=25.609756097561, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=26.4822134387352, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI209862901, Length=224, Percent_Identity=26.3392857142857, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI19923983, Length=224, Percent_Identity=26.3392857142857, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4503817, Length=200, Percent_Identity=29.5, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=28.6307053941909, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=26.3358778625954, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI40254986, Length=200, Percent_Identity=31.5, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=27.6041666666667, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4504505, Length=237, Percent_Identity=27.4261603375527, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=24.3386243386243, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI31542939, Length=192, Percent_Identity=28.6458333333333, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=32.520325203252, Blast_Score=136, Evalue=1e-33, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=31.6205533596838, Blast_Score=124, Evalue=9e-30, Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=33.4600760456274, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=30.4526748971193, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=31.2757201646091, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=30.5555555555556, Blast_Score=107, Evalue=5e-25, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=28.4046692607004, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=28.968253968254, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI1787820, Length=243, Percent_Identity=28.8065843621399, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=26.2745098039216, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787526, Length=250, Percent_Identity=25.6, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=27.4590163934426, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=23.921568627451, Blast_Score=78, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=41.40625, Blast_Score=194, Evalue=4e-50, Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=41.015625, Blast_Score=191, Evalue=3e-49, Organism=Caenorhabditis elegans, GI17561272, Length=240, Percent_Identity=42.0833333333333, Blast_Score=178, Evalue=2e-45, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=30.5660377358491, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=32.4528301886792, Blast_Score=117, Evalue=8e-27, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=33.0708661417323, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=35.7414448669202, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=30.3030303030303, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=33.0769230769231, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.7878787878788, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=32.6923076923077, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=31.4606741573034, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=31.9391634980989, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=30.2788844621514, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=30.6818181818182, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=31.9548872180451, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=30.6451612903226, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=30.6772908366534, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.5660377358491, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=27.0916334661355, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=29.7397769516729, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=31.0861423220974, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=29.1666666666667, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=29.6992481203008, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=27.5471698113208, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=28.3018867924528, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=25, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=30.7291666666667, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=31.5789473684211, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17558628, Length=191, Percent_Identity=32.4607329842932, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71997099, Length=233, Percent_Identity=26.6094420600858, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.6, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17555612, Length=224, Percent_Identity=27.6785714285714, Blast_Score=67, Evalue=9e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=36.5758754863813, Blast_Score=150, Evalue=1e-37, Organism=Saccharomyces cerevisiae, GI6322861, Length=254, Percent_Identity=29.9212598425197, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=239, Percent_Identity=30.1255230125523, Blast_Score=77, Evalue=4e-15, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=34.1176470588235, Blast_Score=128, Evalue=3e-30, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=30.9803921568627, Blast_Score=124, Evalue=8e-29, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=32.8063241106719, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30.8, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=27.9352226720648, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=25.1028806584362, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI17737361, Length=261, Percent_Identity=28.3524904214559, Blast_Score=88, Evalue=4e-18, Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=27.6679841897233, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21357673, Length=191, Percent_Identity=30.3664921465969, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI24580925, Length=194, Percent_Identity=26.2886597938144, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI18859837, Length=243, Percent_Identity=28.3950617283951, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=24.8730964467005, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI21356301, Length=192, Percent_Identity=31.25, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.34 [H]
Molecular weight: Translated: 27647; Mature: 27647
Theoretical pI: Translated: 6.77; Mature: 6.77
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEEAKLEIEQFPGQILTVQMD CCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEE VRNTDDIQKMIEQIDEKFGRIDILINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYCSQ CCCCHHHHHHHHHHHHHHCEEEEEEECCCCCEECCCCCCCCCCHHHEEEEEECCCCHHHH AIGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGVLAMTKTLAVEWGRKYGIRVN HHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE AIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYINGTC EECCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCEEECCEE MTMDGGQHLHQYPF EEECCCCCCCCCCC >Mature Secondary Structure MKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEEAKLEIEQFPGQILTVQMD CCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEE VRNTDDIQKMIEQIDEKFGRIDILINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYCSQ CCCCHHHHHHHHHHHHHHCEEEEEEECCCCCEECCCCCCCCCCHHHEEEEEECCCCHHHH AIGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGVLAMTKTLAVEWGRKYGIRVN HHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE AIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYINGTC EECCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCEEECCEE MTMDGGQHLHQYPF EEECCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]