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The map label for this gene is typA [H]

Identifier: 49186866

GI number: 49186866

Start: 3818689

End: 3820533

Strand: Reverse

Name: typA [H]

Synonym: BAS3868

Alternate gene names: 49186866

Gene position: 3820533-3818689 (Counterclockwise)

Preceding gene: 49186868

Following gene: 49186865

Centisome position: 73.07

GC content: 38.27

Gene sequence:

>1845_bases
ATGTTGAAAAAACGACAAGATTTACGTAATATAGCAATTATTGCCCACGTTGACCATGGTAAAACAACACTTGTTGACCA
GTTATTACGTCAAGCGGGGACTTTCCGTGCGAACGAACACGTTGAAGAACGCGCAATGGATTCAAATGATCTAGAAAGAG
AACGCGGTATTACAATTTTAGCGAAAAATACTGCGATTCACTATGAAGATAAAAGAATTAACATTTTAGATACACCAGGT
CACGCTGACTTCGGTGGAGAAGTAGAACGTATTATGAAAATGGTTGATGGTGTATTACTTGTTGTTGATGCATATGAAGG
TTGTATGCCACAAACACGATTTGTTTTAAAGAAAGCTCTTGAGCAAAACTTAACTCCAATCGTAGTTGTAAATAAAATTG
ACCGTGACTTCGCTCGTCCTGATGAAGTAGTTGATGAAGTAATCGACTTATTCATCGAACTTGGTGCAAACGAAGATCAA
TTAGAGTTCCCAGTTGTATTTGCATCAGCAATGAACGGAACAGCAAGCTTAGATTCAAACCCAGCAAATCAAGAAGAGAA
TATGAAATCATTATTTGATACAATTATTGAACATATTCCTGCACCAATTGATAACAGCGAAGAGCCACTTCAATTCCAAG
TAGCACTTCTTGATTACAACGACTATGTTGGACGTATCGGGGTTGGACGCGTATTCCGCGGTACAATGAAGGTTGGACAA
CAAGTTGCTTTAATGAAAGTAGACGGAAGTGTAAAACAATTCCGCGTAACGAAACTATTTGGTTATATGGGATTAAAACG
TCAAGAAATTGAAGAAGCAAAAGCTGGAGACTTAGTAGCTGTTTCTGGTATGGAAGACATTAACGTAGGTGAAACAGTAT
GTCCAGTTGAACATCAAGATGCGTTACCATTATTACGTATTGATGAGCCAACACTACAAATGACATTCCTTGTAAATAAC
AGCCCATTTGCAGGTCGTGAAGGTAAATACATTACATCTCGTAAAATTGAAGAGCGTCTTCGTTCACAATTAGAAACAGA
TGTAAGTTTACGCGTAGATAATACAGAATCTCCTGATGCGTGGATCGTATCTGGACGTGGGGAACTACATTTATCTATCT
TAATCGAAAACATGCGTCGTGAAGGTTATGAACTACAAGTATCTAAACCAGAAGTAATCATTAAAGAAGTTGATGGCGTA
AGATGTGAGCCTGTAGAGCGTGTGCAAATTGATGTACCTGAAGAATACACTGGTTCTATTATGGAATCTATGGGTGCACG
TAAAGGTGAAATGTTAGATATGGTGAATAACGGAAACGGTCAAGTTCGCCTTACTTTCATGGTTCCAGCACGTGGTTTAA
TTGGTTACACAACAGAATTCTTAACATTAACTCGTGGTTACGGTATTTTAAACCATACATTCGATTGCTACCAACCAGTA
CACGCTGGACAAGTTGGTGGACGTCGTCAAGGTGTTCTAGTTTCACTTGAAACAGGAAAAGCATCACAATACGGTATTAT
GCAAGTTGAAGACCGTGGTGTAATCTTCGTTGAACCAGGTACAGAAGTATATGCTGGTATGATTGTTGGAGAACACACTC
GTGAGAATGACTTAACAGTTAACGTTGTGAAAATGAAACAACAAACTAACATTCGTTCTGCGACAAAAGATCAAACTTCA
ACAATGAAAAAACCACGCTTAATGACTTTAGAAGAGTCATTAGAGTACTTAAACGATGACGAGTTCTGTGAAGTAACTCC
AGAATCAATTCGTTTACGTAAAAAGATTCTTGATAAGAGCGAACGTGAAAGAGCTGCTAAGAAAAAGAAATCTGTAGAAG
CGTAA

Upstream 100 bases:

>100_bases
GAATACAACTATATTTTCATTCTTGATTTTATTTTAATTGCTATTGTATCCCCTTCGCTCTTATAATAGAGAAGGATTAA
AAAGACATTAGGAGTTGGAC

Downstream 100 bases:

>100_bases
AAAATAGAACAGCTATCTTAATTTAAGGTAGCTGTTTTTTTATGTTTATTTTTTAGAATATTTACTCTTTTTAGTGGACA
GTATTTTTTTTGCGGGTTAC

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITILAKNTAIHYEDKRINILDTPG
HADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLKKALEQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQ
LEFPVVFASAMNGTASLDSNPANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQDALPLLRIDEPTLQMTFLVNN
SPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDAWIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGV
RCEPVERVQIDVPEEYTGSIMESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGILNHTFDCYQPV
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTVNVVKMKQQTNIRSATKDQTS
TMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKSERERAAKKKKSVEA

Sequences:

>Translated_614_residues
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITILAKNTAIHYEDKRINILDTPG
HADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLKKALEQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQ
LEFPVVFASAMNGTASLDSNPANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQDALPLLRIDEPTLQMTFLVNN
SPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDAWIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGV
RCEPVERVQIDVPEEYTGSIMESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGILNHTFDCYQPV
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTVNVVKMKQQTNIRSATKDQTS
TMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKSERERAAKKKKSVEA
>Mature_614_residues
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITILAKNTAIHYEDKRINILDTPG
HADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLKKALEQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQ
LEFPVVFASAMNGTASLDSNPANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQDALPLLRIDEPTLQMTFLVNN
SPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDAWIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGV
RCEPVERVQIDVPEEYTGSIMESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGILNHTFDCYQPV
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTVNVVKMKQQTNIRSATKDQTS
TMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKSERERAAKKKKSVEA

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=522, Percent_Identity=28.1609195402299, Blast_Score=156, Evalue=7e-38,
Organism=Homo sapiens, GI94966754, Length=137, Percent_Identity=44.5255474452555, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI4503483, Length=151, Percent_Identity=36.4238410596026, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI18390331, Length=197, Percent_Identity=34.010152284264, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI19923640, Length=168, Percent_Identity=35.1190476190476, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI25306287, Length=168, Percent_Identity=35.1190476190476, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI25306283, Length=168, Percent_Identity=35.1190476190476, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310132016, Length=115, Percent_Identity=41.7391304347826, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI310110807, Length=115, Percent_Identity=41.7391304347826, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI310123363, Length=115, Percent_Identity=41.7391304347826, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI34147630, Length=274, Percent_Identity=31.7518248175182, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI217272894, Length=198, Percent_Identity=30.8080808080808, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI217272892, Length=198, Percent_Identity=30.8080808080808, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI94966752, Length=133, Percent_Identity=32.3308270676692, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI53729339, Length=138, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI53729337, Length=138, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI48994988, Length=603, Percent_Identity=54.5605306799337, Blast_Score=691, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=512, Percent_Identity=28.515625, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789738, Length=178, Percent_Identity=38.7640449438202, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=35.1724137931034, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790412, Length=282, Percent_Identity=28.3687943262411, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789737, Length=282, Percent_Identity=28.3687943262411, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789559, Length=166, Percent_Identity=34.3373493975904, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17557151, Length=513, Percent_Identity=25.5360623781676, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17556745, Length=442, Percent_Identity=26.4705882352941, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17533571, Length=175, Percent_Identity=38.2857142857143, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17506493, Length=163, Percent_Identity=32.5153374233129, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71988811, Length=133, Percent_Identity=36.8421052631579, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988819, Length=133, Percent_Identity=36.8421052631579, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=36.5671641791045, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=316, Percent_Identity=28.4810126582279, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25141371, Length=278, Percent_Identity=26.978417266187, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71994658, Length=235, Percent_Identity=28.5106382978723, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=515, Percent_Identity=28.1553398058252, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324707, Length=211, Percent_Identity=36.4928909952607, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6320593, Length=211, Percent_Identity=36.4928909952607, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6324761, Length=275, Percent_Identity=31.2727272727273, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323098, Length=206, Percent_Identity=34.4660194174757, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322359, Length=148, Percent_Identity=36.4864864864865, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324550, Length=144, Percent_Identity=35.4166666666667, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI78706572, Length=518, Percent_Identity=25.8687258687259, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28574573, Length=142, Percent_Identity=41.5492957746479, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24585709, Length=155, Percent_Identity=36.7741935483871, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24585711, Length=154, Percent_Identity=37.012987012987, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24585713, Length=154, Percent_Identity=37.012987012987, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24582462, Length=195, Percent_Identity=34.8717948717949, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357743, Length=188, Percent_Identity=36.1702127659575, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI281363316, Length=294, Percent_Identity=31.2925170068027, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17864358, Length=294, Percent_Identity=31.2925170068027, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI221458488, Length=161, Percent_Identity=40.9937888198758, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19921738, Length=298, Percent_Identity=28.1879194630872, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28572034, Length=165, Percent_Identity=33.9393939393939, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 69035; Mature: 69035

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITIL
CCCCHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHCCEEEE
AKNTAIHYEDKRINILDTPGHADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLKKAL
EECCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQLEFPVVFASAMNGTASLDSN
HCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCC
PANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCC
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQD
EEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCEECCCCCCC
ALPLLRIDEPTLQMTFLVNNSPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDA
CCCEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEECCCCCCCE
WIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGVRCEPVERVQIDVPEEYTGSI
EEEECCCCEEEEEEEHHHHCCCCEEEECCCCEEEEECCCCCCCCCCEEEEECCHHHHHHH
MESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGILNHTFDCYQPV
HHHHCCCCCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCC
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTV
CCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEECCCCCEEEEEEEECCCCCCCCEE
NVVKMKQQTNIRSATKDQTSTMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKS
EEEEEEHHCCCHHCCCHHHHHHCCCCEEEHHHHHHHCCCCCCEEECHHHHHHHHHHHCHH
ERERAAKKKKSVEA
HHHHHHHHHHCCCC
>Mature Secondary Structure
MLKKRQDLRNIAIIAHVDHGKTTLVDQLLRQAGTFRANEHVEERAMDSNDLERERGITIL
CCCCHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHCCEEEE
AKNTAIHYEDKRINILDTPGHADFGGEVERIMKMVDGVLLVVDAYEGCMPQTRFVLKKAL
EECCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQNLTPIVVVNKIDRDFARPDEVVDEVIDLFIELGANEDQLEFPVVFASAMNGTASLDSN
HCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCC
PANQEENMKSLFDTIIEHIPAPIDNSEEPLQFQVALLDYNDYVGRIGVGRVFRGTMKVGQ
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCC
QVALMKVDGSVKQFRVTKLFGYMGLKRQEIEEAKAGDLVAVSGMEDINVGETVCPVEHQD
EEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEECCCCCCCCCCEECCCCCCC
ALPLLRIDEPTLQMTFLVNNSPFAGREGKYITSRKIEERLRSQLETDVSLRVDNTESPDA
CCCEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEECCCCCCCE
WIVSGRGELHLSILIENMRREGYELQVSKPEVIIKEVDGVRCEPVERVQIDVPEEYTGSI
EEEECCCCEEEEEEEHHHHCCCCEEEECCCCEEEEECCCCCCCCCCEEEEECCHHHHHHH
MESMGARKGEMLDMVNNGNGQVRLTFMVPARGLIGYTTEFLTLTRGYGILNHTFDCYQPV
HHHHCCCCCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCC
HAGQVGGRRQGVLVSLETGKASQYGIMQVEDRGVIFVEPGTEVYAGMIVGEHTRENDLTV
CCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEECCCCCEEEEEEEECCCCCCCCEE
NVVKMKQQTNIRSATKDQTSTMKKPRLMTLEESLEYLNDDEFCEVTPESIRLRKKILDKS
EEEEEEHHCCCHHCCCHHHHHHCCCCEEEHHHHHHHCCCCCCEEECHHHHHHHHHHHCHH
ERERAAKKKKSVEA
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]