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The map label for this gene is catQ [H]

Identifier: 49185254

GI number: 49185254

Start: 2247047

End: 2247697

Strand: Direct

Name: catQ [H]

Synonym: BAS2245

Alternate gene names: 49185254

Gene position: 2247047-2247697 (Clockwise)

Preceding gene: 49185252

Following gene: 49185255

Centisome position: 42.98

GC content: 29.49

Gene sequence:

>651_bases
ATGAAGTTTCACGTAATTGATAGGGAAAATTGGAATAGAGAGCAGTATTTCGAACACTATTTAGAATTAAAATGTACGTT
TAGTATGACAGTAAATGTTGATATTACGCTTTTGATAAAGAAAGTACATCAAAAGGGAATTAAATTTTATCCGACTTTTA
TTTATATAATTTCGAGAATAATAAATAAACATAAAGAATTTCGAACATGTTTTAACGATGAAGGAGTTTTAGGCTATTGG
GAGGAAATGATCCCGAGTTATACAATCTTTCATAAAGATGATAAGTCTTTTTCAAGTATATGGACGGATTATTCAAGTGA
TTTCCGCATTTTCTATAAAAATTATGAAGAAGATATGAGATGTTATGCTAGTGTTCATGGTCTTTTAACGAAAGAAAATA
TTCCGCCTAATATATTTCCGATTTCTGGCATACCTTGGACTAGTTTTACTGGATTTAATCTTAACATTAATAATGATGGT
GATTTTCTATTACCTATTATAACTTGTGGGAAATATTTTAATGAAGAAAATAAGATTATGCTACCAGTTTCATTGCAAGT
TCATCATTCGGTTTGTGATGGATATCATGTAAGTCGATTTATAGAGGATTTACAGGAGTTAAGTAATAGTTGCAACGAGT
GGCTTAAGTAA

Upstream 100 bases:

>100_bases
TAATTAGGGTGAAATATAAACTGTTAGGAGTGAACAATTATGGTGAAAGCAAGGAAATTAGCCTTCTAAAATAAAAAGAA
AATTTTAGGAGGCTATTAAA

Downstream 100 bases:

>100_bases
TATCTAATTTTTAATTATATGCAATTGAAAATGAATAAAAGAAGAGACCATGTTTTTATTACATGTTCTCTTTTTTATTC
ATTAATACTGAGTTACAGTG

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: CAT [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKFHVIDRENWNREQYFEHYLELKCTFSMTVNVDITLLIKKVHQKGIKFYPTFIYIISRIINKHKEFRTCFNDEGVLGYW
EEMIPSYTIFHKDDKSFSSIWTDYSSDFRIFYKNYEEDMRCYASVHGLLTKENIPPNIFPISGIPWTSFTGFNLNINNDG
DFLLPIITCGKYFNEENKIMLPVSLQVHHSVCDGYHVSRFIEDLQELSNSCNEWLK

Sequences:

>Translated_216_residues
MKFHVIDRENWNREQYFEHYLELKCTFSMTVNVDITLLIKKVHQKGIKFYPTFIYIISRIINKHKEFRTCFNDEGVLGYW
EEMIPSYTIFHKDDKSFSSIWTDYSSDFRIFYKNYEEDMRCYASVHGLLTKENIPPNIFPISGIPWTSFTGFNLNINNDG
DFLLPIITCGKYFNEENKIMLPVSLQVHHSVCDGYHVSRFIEDLQELSNSCNEWLK
>Mature_216_residues
MKFHVIDRENWNREQYFEHYLELKCTFSMTVNVDITLLIKKVHQKGIKFYPTFIYIISRIINKHKEFRTCFNDEGVLGYW
EEMIPSYTIFHKDDKSFSSIWTDYSSDFRIFYKNYEEDMRCYASVHGLLTKENIPPNIFPISGIPWTSFTGFNLNINNDG
DFLLPIITCGKYFNEENKIMLPVSLQVHHSVCDGYHVSRFIEDLQELSNSCNEWLK

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 25765; Mature: 25765

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00100 CAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFHVIDRENWNREQYFEHYLELKCTFSMTVNVDITLLIKKVHQKGIKFYPTFIYIISRI
CEEEEECCCCCCHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHCCCEEHHHHHHHHHHH
INKHKEFRTCFNDEGVLGYWEEMIPSYTIFHKDDKSFSSIWTDYSSDFRIFYKNYEEDMR
HHHHHHHHHHCCCCCCCHHHHHHCCCEEEEECCCCHHHHHHCCCCCCEEEEECCHHHHHH
CYASVHGLLTKENIPPNIFPISGIPWTSFTGFNLNINNDGDFLLPIITCGKYFNEENKIM
HHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCCCCEE
LPVSLQVHHSVCDGYHVSRFIEDLQELSNSCNEWLK
EEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFHVIDRENWNREQYFEHYLELKCTFSMTVNVDITLLIKKVHQKGIKFYPTFIYIISRI
CEEEEECCCCCCHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHCCCEEHHHHHHHHHHH
INKHKEFRTCFNDEGVLGYWEEMIPSYTIFHKDDKSFSSIWTDYSSDFRIFYKNYEEDMR
HHHHHHHHHHCCCCCCCHHHHHHCCCEEEEECCCCHHHHHHCCCCCCEEEEECCHHHHHH
CYASVHGLLTKENIPPNIFPISGIPWTSFTGFNLNINNDGDFLLPIITCGKYFNEENKIM
HHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCCCCEE
LPVSLQVHHSVCDGYHVSRFIEDLQELSNSCNEWLK
EEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2039197 [H]