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The map label for this gene is ileS

Identifier: 49185038

GI number: 49185038

Start: 2032953

End: 2036054

Strand: Direct

Name: ileS

Synonym: BAS2027

Alternate gene names: 49185038

Gene position: 2032953-2036054 (Clockwise)

Preceding gene: 49185037

Following gene: 49185039

Centisome position: 38.88

GC content: 37.56

Gene sequence:

>3102_bases
ATGAAGAAAGTAGATGTAAAAGAATCAGCTGTAGGAAGAGAAATGCGAATTCGCAAACAGTGGAACGAACAAAATATTTT
CGAACAATCAATTCAGAATCGAGAAGGCGCACAATCTTTTGTGTTTTATGAAGGACCACCGACGGCGAATGGATTACCGC
ATGTAGGTCATGCACTTGGACGAACAATTAAAGATGTAGTAGCAAGATATAAAACGATGGCTGGTTATAAAGTATTAAGA
AAAGCGGGATGGGATACGCACGGCTTACCTGTAGAATTAGGTGTTGAGAAGCAACTCGGTATTTCTGGTAAACATGAAAT
CGAGGAGTACGGAATTGAACCATTTATTAAAAAGTGTAAAGAGAGTGTATTCACATATGAAAAGCAGTGGCGTGAATTCA
CTGAAAGCATCGGTTATTGGGTAGATATGGATGATCCATACGTTACGTTAGAGAATCCATATATCGAAAGTGTATGGCAT
ATTTTAGGGACGATTCATGAAAAAGGATTATTGTATAAAGGGCATAGAGTTTCACCATATTGCCCAAGCTGTCAAACTTC
ACTAAGTTCACATGAGGTTGCCCAAGGGTATAAAACAGTAAAAGATTTAAGTGCAACCGTTAAGTTTAAAGTGAAGGATA
GTGAAAATGAATATTTCCTAGGTTGGACGACAACACCTTGGACACTTCCAGCAAATGTTGCACTCGCTGTACATCCAAAT
ATGGAATACGTGAAAGCAAAACAAGAAGGTCATGTATACATTGTTGCGAAAGAACGTGTACAAGATGTATTAAAAGAAAA
CTATGAAGTATTATCTGTTCATAAAGGAGAAGAATTATTAAATATTTCTTATACAGCACCGTTTCCGATGAAAGAAGTTA
CAAATGGTTACCGCGTTATCGGAGCAGATTTTGTAACGGCAGATAGTGGTACAGGACTTGTTCATATTGCTCCAGCATAC
GGAGAGGACGATTATAGAGTCGTGCAAAGTGAAGGATTGTCCTTCTTACATGTTGTAGATGAGAAAGGTGAGTATACAGA
GGCAGTACCATTTTTGAAAGGGAAGTTTGTAAAAGATTGTGACGTAGATATCGTTCGTTATTTAGCGAAGGAAGATTTAC
TATACCATAAAGAAAAGTATGAACACAGTTACCCACATTGTTGGCGCTGTGATTCACCACTTCTTTATTATGCAGGAGAG
AGCTGGTTAATCCGCACGACTGCAATTAAAGATACATTTTTACAAAACAACGATACTGTTACTTGGTATCCAGATCATAT
GAAACATGGACGATTTGGTAAGTTTTTAGAAAACATGGTGGACTGGAATATTAGCCGAAATAGATATTGGGGAACACCAT
TAAACGTATGGGAATGTGAACGTTGCGATCATCAATTCGCACCGAAAAGCATTGCTGATTTAAGAAAGCATAGTATGAAA
GAGACACCTGAAGACTTAGAATTGCATAAGCCATATGTAGATGAAGTGCAAGTTTGCTGCGAAAAATGCGGAAGTACAAT
GAATCGTACACCAGAAGTAATTGATGTTTGGTTTGATAGTGGTTCGATGCCATTTGCGCAATATCATTATCCGTTTGAAA
ATAAAGAGTTATTTGAAGAACAGTTTCCAGCAGATGTAATTGCAGAAGGAATTGATCAAACACGCGGCTGGTTTTATAGT
TTATTAGCTGTATCAGCACTATATACTGGAAAAGTACCGTATAAACGAGTGCTATCACTAGGGCATGTTCTAGACGAGGA
AGGACAGAAAATGTCTAAAAGTAAAGGGAATGCACTAGATCCAGTTGATTTAGTAGGGAAGTTTGGTGCAGATGCTTTAA
GATGGGCTCTACTTGTTGATAGTGCTCTGTGGAATGCGAAACGTTTTTCTGAAAGAACAGTACTGGAAGCGAAATCTAAA
TTTGTAGATACGTTAGTCAATGTGTATAGCTTCTACGTTTTATATGCAAATTTAGATGAGTATAATCCGAATGAAACATA
TGACGTAAAGCGGACGAAATTGGATGAATGGGTATTATCAAGATTGCATAGCACAACGAAAAAAGTGAGAACAGCACTTG
ATGATTATCAATTTACGAATGCAGCTCGTGAAATCGCGGCACTTGTAGATGAAGTAAGTAACTGGTACGTAAGACGATCA
CGTAATCGTTTCTGGGAATCGGGTATGAATGCGGAAAAAGCAGCTGCGTATGAAACACTTCATGACGTGCTTGTGACAAT
TAGTAAATTAATCGCACCGTTTACACCGTTTGTCGCTGAAGATGTTCATTTGAATTTAACTGGAAGTAGCGTTCATCTAG
AGGATTATCCAGTTGTAAATGAATCATTACTTCAGCCGAAATTAGAAGCGGAAATGGATGCTGTTTTACAAGTTGTTGAA
CTTGGAAGAAGTAACCGTAATCAGCATTCTTTAAAAGTAAAACAGCCGTTAGCGGAACTTGTACTACTTGAGCATAATGA
AAATGATATGGACTGGGAATCTTATCGTGATATCGTCATGGATGAGTTAAATGTGAAGGCGTTCCATGTTGAACTAGATG
AAACGAAATATACATCCTATCAATTAAAACTGAATTTTAAAAAGGCTGGGCCGAAGTTCGGTAAAAATGTGAATGCAGTA
AATGGCTGGCTAAAACAATTATCACAAGACGAGGTACAGAACTTTGTCTCTACAGAAAGAGCAGTTTACGAAGTAGCACC
AGGAGAAGAAATAGTTGTAACGACTGAAGATGTATTAGTAGAGAAAGTTGCAAAATCAGGATTCTCTAATACGACTAACG
GACAATATACAGTTATGTTAGATACGAATGTAACGGAAGAATTGTTACAAGAAGGAGTAGCACGTGAGTTTATTCGCGCC
GTTCAAGAATATCGTAAGCAGTTGAATTTACCAGTAAATTTACGAGTGGATGTTATTCTTGATACAGAGGAAGAGCTACA
GCAAACGTTAACGAATCATAAAGAGTTGTTGGAAGAAAACTTACTCGTTAAACAATTTACATTTGGTCACTTAACGAATG
AAGACGATGAACTTTCTTTAGGTGAGACAAAAGTCCGCATTAAATTAAGTACTGCTCAGTAA

Upstream 100 bases:

>100_bases
GAACTAATAGAATTAGGGTGGTATCGCGGGTAAACCCGTCCCTACTTTATAGGGACGGGTTTTTTGTGTGCTTTAAAACA
TTCAAAAGGAGTGATTGTAG

Downstream 100 bases:

>100_bases
AGAAAAAAGGAAGTTGGAATGATTCCAACTTCCTTTTTGTGTGCTGGAAATGTATCCTGTTATTTTCCACATAATCCATT
CGATAGGACCTCTAGCACAT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase 2; IleRS 2

Number of amino acids: Translated: 1033; Mature: 1033

Protein sequence:

>1033_residues
MKKVDVKESAVGREMRIRKQWNEQNIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMAGYKVLR
KAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWH
ILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVIGADFVTADSGTGLVHIAPAY
GEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDCDVDIVRYLAKEDLLYHKEKYEHSYPHCWRCDSPLLYYAGE
SWLIRTTAIKDTFLQNNDTVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECERCDHQFAPKSIADLRKHSMK
ETPEDLELHKPYVDEVQVCCEKCGSTMNRTPEVIDVWFDSGSMPFAQYHYPFENKELFEEQFPADVIAEGIDQTRGWFYS
LLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVGKFGADALRWALLVDSALWNAKRFSERTVLEAKSK
FVDTLVNVYSFYVLYANLDEYNPNETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDVHLNLTGSSVHLEDYPVVNESLLQPKLEAEMDAVLQVVE
LGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKAFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAV
NGWLKQLSQDEVQNFVSTERAVYEVAPGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSLGETKVRIKLSTAQ

Sequences:

>Translated_1033_residues
MKKVDVKESAVGREMRIRKQWNEQNIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMAGYKVLR
KAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWH
ILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVIGADFVTADSGTGLVHIAPAY
GEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDCDVDIVRYLAKEDLLYHKEKYEHSYPHCWRCDSPLLYYAGE
SWLIRTTAIKDTFLQNNDTVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECERCDHQFAPKSIADLRKHSMK
ETPEDLELHKPYVDEVQVCCEKCGSTMNRTPEVIDVWFDSGSMPFAQYHYPFENKELFEEQFPADVIAEGIDQTRGWFYS
LLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVGKFGADALRWALLVDSALWNAKRFSERTVLEAKSK
FVDTLVNVYSFYVLYANLDEYNPNETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDVHLNLTGSSVHLEDYPVVNESLLQPKLEAEMDAVLQVVE
LGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKAFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAV
NGWLKQLSQDEVQNFVSTERAVYEVAPGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSLGETKVRIKLSTAQ
>Mature_1033_residues
MKKVDVKESAVGREMRIRKQWNEQNIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMAGYKVLR
KAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWH
ILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVIGADFVTADSGTGLVHIAPAY
GEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDCDVDIVRYLAKEDLLYHKEKYEHSYPHCWRCDSPLLYYAGE
SWLIRTTAIKDTFLQNNDTVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECERCDHQFAPKSIADLRKHSMK
ETPEDLELHKPYVDEVQVCCEKCGSTMNRTPEVIDVWFDSGSMPFAQYHYPFENKELFEEQFPADVIAEGIDQTRGWFYS
LLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVGKFGADALRWALLVDSALWNAKRFSERTVLEAKSK
FVDTLVNVYSFYVLYANLDEYNPNETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDVHLNLTGSSVHLEDYPVVNESLLQPKLEAEMDAVLQVVE
LGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKAFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAV
NGWLKQLSQDEVQNFVSTERAVYEVAPGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSLGETKVRIKLSTAQ

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1034, Percent_Identity=36.1702127659575, Blast_Score=638, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1034, Percent_Identity=36.1702127659575, Blast_Score=638, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=769, Percent_Identity=30.1690507152146, Blast_Score=285, Evalue=2e-76,
Organism=Homo sapiens, GI268370293, Length=885, Percent_Identity=22.5988700564972, Blast_Score=157, Evalue=5e-38,
Organism=Homo sapiens, GI268370297, Length=885, Percent_Identity=22.5988700564972, Blast_Score=157, Evalue=7e-38,
Organism=Homo sapiens, GI268370295, Length=857, Percent_Identity=22.7537922987165, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI5454158, Length=879, Percent_Identity=23.094425483504, Blast_Score=146, Evalue=8e-35,
Organism=Escherichia coli, GI2367096, Length=788, Percent_Identity=29.8223350253807, Blast_Score=344, Evalue=2e-95,
Organism=Escherichia coli, GI1790708, Length=894, Percent_Identity=22.7069351230425, Blast_Score=182, Evalue=7e-47,
Organism=Escherichia coli, GI1786861, Length=376, Percent_Identity=21.8085106382979, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17541896, Length=988, Percent_Identity=38.1578947368421, Blast_Score=668, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=788, Percent_Identity=28.0456852791878, Blast_Score=262, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI17510661, Length=868, Percent_Identity=23.6175115207373, Blast_Score=182, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI72001587, Length=877, Percent_Identity=23.2611174458381, Blast_Score=179, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6319395, Length=997, Percent_Identity=35.3059177532598, Blast_Score=624, Evalue=1e-179,
Organism=Saccharomyces cerevisiae, GI6325217, Length=782, Percent_Identity=26.2148337595908, Blast_Score=244, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6321531, Length=845, Percent_Identity=24.2603550295858, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI28574730, Length=1052, Percent_Identity=36.3117870722433, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1052, Percent_Identity=36.3117870722433, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1052, Percent_Identity=36.3117870722433, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=787, Percent_Identity=28.843710292249, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI17864482, Length=875, Percent_Identity=23.8857142857143, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24653289, Length=875, Percent_Identity=23.8857142857143, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21355675, Length=605, Percent_Identity=24.297520661157, Blast_Score=142, Evalue=1e-33,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI2_BACAN (Q81R75)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_844574.1
- RefSeq:   YP_018823.1
- RefSeq:   YP_028290.1
- ProteinModelPortal:   Q81R75
- SMR:   Q81R75
- IntAct:   Q81R75
- EnsemblBacteria:   EBBACT00000012473
- EnsemblBacteria:   EBBACT00000014521
- EnsemblBacteria:   EBBACT00000020455
- GeneID:   1085720
- GeneID:   2815690
- GeneID:   2849029
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_2181
- KEGG:   bar:GBAA_2181
- KEGG:   bat:BAS2027
- TIGR:   BA_2181
- TIGR:   GBAA_2181
- GeneTree:   EBGT00070000031886
- HOGENOM:   HBG577712
- OMA:   VEYEVEK
- ProtClustDB:   PRK06039
- BioCyc:   BANT260799:BAS2027-MONOMER
- BioCyc:   BANT261594:GBAA2181-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 118654; Mature: 118654

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 593-593

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVDVKESAVGREMRIRKQWNEQNIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALG
CCCCCCCHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHH
RTIKDVVARYKTMAGYKVLRKAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHCCCCCCHHHHHCCCCHHHHHHH
ESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWHILGTIHEKGLLYKGHRVSPY
HHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCC
CPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
CCCHHHCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCC
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVI
HHHHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCHHHHCCCEEEE
GADFVTADSGTGLVHIAPAYGEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDC
EEEEEEECCCCCEEEEECCCCCCCCEEHHHCCCEEEEEECCCCCHHHHCHHHCCCCCCCC
DVDIVRYLAKEDLLYHKEKYEHSYPHCWRCDSPLLYYAGESWLIRTTAIKDTFLQNNDTV
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEHHHHHHCCCCCEE
TWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECERCDHQFAPKSIADLRKHSMK
EECCCHHCCCCHHHHHHHHHCCCCCCCEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
ETPEDLELHKPYVDEVQVCCEKCGSTMNRTPEVIDVWFDSGSMPFAQYHYPFENKELFEE
CCCCHHHCCCCCHHHHHHHHHHHCHHCCCCCCEEEEEECCCCCCHHEECCCCCCHHHHHH
QFPADVIAEGIDQTRGWFYSLLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PVDLVGKFGADALRWALLVDSALWNAKRFSERTVLEAKSKFVDTLVNVYSFYVLYANLDE
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
YNPNETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDVHLNLTGSSVHLEDYPVVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEECCEEEECCCCCCC
ESLLQPKLEAEMDAVLQVVELGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVM
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHEEEECCCCCCCHHHHHHHHH
DELNVKAFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAVNGWLKQLSQDEVQNFVSTER
HCCCEEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVYEVAPGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
HEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSL
HHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCC
GETKVRIKLSTAQ
CCEEEEEEEECCC
>Mature Secondary Structure
MKKVDVKESAVGREMRIRKQWNEQNIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALG
CCCCCCCHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHH
RTIKDVVARYKTMAGYKVLRKAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHCCCCCCHHHHHCCCCHHHHHHH
ESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWHILGTIHEKGLLYKGHRVSPY
HHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCC
CPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
CCCHHHCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCC
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVI
HHHHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCHHHHCCCEEEE
GADFVTADSGTGLVHIAPAYGEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDC
EEEEEEECCCCCEEEEECCCCCCCCEEHHHCCCEEEEEECCCCCHHHHCHHHCCCCCCCC
DVDIVRYLAKEDLLYHKEKYEHSYPHCWRCDSPLLYYAGESWLIRTTAIKDTFLQNNDTV
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEHHHHHHCCCCCEE
TWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECERCDHQFAPKSIADLRKHSMK
EECCCHHCCCCHHHHHHHHHCCCCCCCEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
ETPEDLELHKPYVDEVQVCCEKCGSTMNRTPEVIDVWFDSGSMPFAQYHYPFENKELFEE
CCCCHHHCCCCCHHHHHHHHHHHCHHCCCCCCEEEEEECCCCCCHHEECCCCCCHHHHHH
QFPADVIAEGIDQTRGWFYSLLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PVDLVGKFGADALRWALLVDSALWNAKRFSERTVLEAKSKFVDTLVNVYSFYVLYANLDE
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
YNPNETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIAALVDEVSNWYVRRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDVHLNLTGSSVHLEDYPVVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEEECCEEEECCCCCCC
ESLLQPKLEAEMDAVLQVVELGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVM
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHEEEECCCCCCCHHHHHHHHH
DELNVKAFHVELDETKYTSYQLKLNFKKAGPKFGKNVNAVNGWLKQLSQDEVQNFVSTER
HCCCEEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVYEVAPGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
HEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSL
HHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCC
GETKVRIKLSTAQ
CCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629