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The map label for this gene is argS [H]

Identifier: 49185032

GI number: 49185032

Start: 2024593

End: 2026281

Strand: Direct

Name: argS [H]

Synonym: BAS2021

Alternate gene names: 49185032

Gene position: 2024593-2026281 (Clockwise)

Preceding gene: 49185031

Following gene: 49185033

Centisome position: 38.72

GC content: 35.76

Gene sequence:

>1689_bases
ATGGATTATAAAACGCAGTTTGCGGAAAGTTTATCTAATATTTTTACGAATGAATTAACGCAACAGCAAATTTTAGATTT
AATTGAAACACCGAAACAAGATGAATTTGGAGATGCTGCATTTCCGTGTTTTTCACTTGCGAAGCAATATAAAAAATCAC
CAGCTATTATCGCAAAGGAAGTTGCAGAGAAATTAAGTGATCCGTTTTTTACGAAAGTAGAGGCTGTTGGTCCTTATGTA
AATGTATTTTTTAATCGTGATACAGTAAGTGATGCAGTATTAAAAACGATTTTAGCGGAGAAAGAAGAGTACGGTAAAAA
TTATTTTGGATGTGAAAAAACGGTCGTTATCGATTATTCCTCACCTAATATCGCGAAACCTTTTTCAATGGGGCATTTAC
GTTCTACAATGATTGGAAATTCATTGAAGCATATCGCTGAAAAATGTGGGTATGAAGTTGTAGGAATTAATTATATTGGA
GACTGGGGAACACAGTTTGGAAAGTTAATTACGGCTTATAAAAAATGGGGAAATGAAGCAGTAGTGAAAGAGGATCCAAT
ACGTGAATTATTTAAGTTATATGTTCAATTTCATGAAGAGGTAAAAGACGACGAAGAATTAGAAGAAGAAGGACGCGCTT
GGTTTAAGAAATTAGAAGAAGGTGATGAAGAAGCTGTTGAACTTTGGAATTGGTTCCGCCACGAATCCTTAAAAGAATTT
TCTCGTATTTATGAACTTCTCGGTGTGGAATTTACTAATTTTCAAGGAGAAGCTTTTTATAATAATTTAATGGAAGACTT
TATTGGGATTTTAGAGGAACATGATTTACTTGAAGAGTCAGAAGGTGCATTAGTCGTTAATTTAGAAGAAGAGGGCATGC
CACCTTGCTTAATTAGAAAATCAGATGGTGCGACGATTTACGCAACGCGTGACTTAACGGCAGCTCTATATCGTCAAAAC
ACATTTGGTTTTGATAAAGCGTTATACGTAGTTGGCCCAGAACAAAGTTTACACTTCAATCAATTCTTCACTGTATTAAA
AAAGCTCGGCTACACTTGGGTTGATGGCATGGAACATGTACCGTTTGGGTTCATTTTAAAAGACGGTAAGAAAATGTCCA
CACGTAAAGGAAGAGTTATTTTACTTGAAGAAGTACTTGAGGAAGCAATCGAACTTGCAAAACAAAATATTGAAGAGAAA
AATCCAAACTTGAAACAGAAAGAAGAAGTAGCAAAGCAAGTCGGCGCTGGCGCAGTCATCTTCCACGATTTAAAAAATGA
GCGTATGCACAATATTGAATTCTCATTAGAAAATATGCTGAAATTCGAAGGGGAAACAGGCCCGTACGTACAATACACAC
ATGCACGTGCTTGCTCTATTTTAAGAAAAGAAAGTGTAGAATTTGAAACGTGTACATTTGCATTAAAAGATGATCATAGC
TGGAGTGTTGTAAAATTACTCAATAAATTCCCACAAGTAATTGAAATAGCCTTCAACAAAAATGAACCATCGGTTATTTC
GAAATACGTATTAGATGTAGCGCAATCGTTTAATAAATATTACGGGAATGTGCGTATATTAGAAGAGAGTGAAGAGAAAG
ACAGTAGACTGGCATTAGTGTATGCTGTGACGGTTGTATTAAAAGAGGGGTTACGTTTACTTGGGGTGGAGGCACCTGAG
GAGATGTAA

Upstream 100 bases:

>100_bases
AGTGGTTCGTAATGAACAACAAGGGTGGTACCACGGGTTCAAACTCGTCTCTTTTTTAGAGACGAGTTTTTTGTGTTTTA
AAAAATAAGGAGGGTGTAGT

Downstream 100 bases:

>100_bases
CATAGTAATAAACTGACAAACTGGGTTTAGTATATAAACCTGGTTTGTTTTTTATTTGGATATATAATTAATTTTCAAAA
TCAATTAAAATCTTTTTAGA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase 1; ArgRS 1 [H]

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MDYKTQFAESLSNIFTNELTQQQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKEVAEKLSDPFFTKVEAVGPYV
NVFFNRDTVSDAVLKTILAEKEEYGKNYFGCEKTVVIDYSSPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIG
DWGTQFGKLITAYKKWGNEAVVKEDPIRELFKLYVQFHEEVKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRKSDGATIYATRDLTAALYRQN
TFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHVPFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEK
NPNLKQKEEVAKQVGAGAVIFHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFALKDDHS
WSVVKLLNKFPQVIEIAFNKNEPSVISKYVLDVAQSFNKYYGNVRILEESEEKDSRLALVYAVTVVLKEGLRLLGVEAPE
EM

Sequences:

>Translated_562_residues
MDYKTQFAESLSNIFTNELTQQQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKEVAEKLSDPFFTKVEAVGPYV
NVFFNRDTVSDAVLKTILAEKEEYGKNYFGCEKTVVIDYSSPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIG
DWGTQFGKLITAYKKWGNEAVVKEDPIRELFKLYVQFHEEVKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRKSDGATIYATRDLTAALYRQN
TFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHVPFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEK
NPNLKQKEEVAKQVGAGAVIFHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFALKDDHS
WSVVKLLNKFPQVIEIAFNKNEPSVISKYVLDVAQSFNKYYGNVRILEESEEKDSRLALVYAVTVVLKEGLRLLGVEAPE
EM
>Mature_562_residues
MDYKTQFAESLSNIFTNELTQQQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKEVAEKLSDPFFTKVEAVGPYV
NVFFNRDTVSDAVLKTILAEKEEYGKNYFGCEKTVVIDYSSPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIG
DWGTQFGKLITAYKKWGNEAVVKEDPIRELFKLYVQFHEEVKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRKSDGATIYATRDLTAALYRQN
TFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHVPFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEK
NPNLKQKEEVAKQVGAGAVIFHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFALKDDHS
WSVVKLLNKFPQVIEIAFNKNEPSVISKYVLDVAQSFNKYYGNVRILEESEEKDSRLALVYAVTVVLKEGLRLLGVEAPE
EM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=512, Percent_Identity=35.546875, Blast_Score=321, Evalue=1e-87,
Organism=Homo sapiens, GI15149476, Length=568, Percent_Identity=29.0492957746479, Blast_Score=222, Evalue=7e-58,
Organism=Escherichia coli, GI1788184, Length=551, Percent_Identity=33.7568058076225, Blast_Score=286, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI71985061, Length=569, Percent_Identity=30.2284710017575, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71985068, Length=533, Percent_Identity=30.7692307692308, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17532153, Length=492, Percent_Identity=29.0650406504065, Blast_Score=192, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6320548, Length=560, Percent_Identity=37.1428571428571, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6321883, Length=560, Percent_Identity=35, Blast_Score=348, Evalue=2e-96,
Organism=Drosophila melanogaster, GI28571570, Length=466, Percent_Identity=32.618025751073, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI18859963, Length=567, Percent_Identity=29.8059964726631, Blast_Score=221, Evalue=9e-58,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64471; Mature: 64471

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKTQFAESLSNIFTNELTQQQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VAEKLSDPFFTKVEAVGPYVNVFFNRDTVSDAVLKTILAEKEEYGKNYFGCEKTVVIDYS
HHHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC
SPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIGDWGTQFGKLITAYKKWGNEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCC
VVKEDPIRELFKLYVQFHEEVKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRK
HHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEE
SDGATIYATRDLTAALYRQNTFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHV
CCCCEEEEECHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCC
PFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEKNPNLKQKEEVAKQVGAGAVI
CEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEE
FHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFALKDDHS
EEHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCC
WSVVKLLNKFPQVIEIAFNKNEPSVISKYVLDVAQSFNKYYGNVRILEESEEKDSRLALV
HHHHHHHHHCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
YAVTVVLKEGLRLLGVEAPEEM
HHHHHHHHHCHHHCCCCCCCCC
>Mature Secondary Structure
MDYKTQFAESLSNIFTNELTQQQILDLIETPKQDEFGDAAFPCFSLAKQYKKSPAIIAKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VAEKLSDPFFTKVEAVGPYVNVFFNRDTVSDAVLKTILAEKEEYGKNYFGCEKTVVIDYS
HHHHHCCCHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC
SPNIAKPFSMGHLRSTMIGNSLKHIAEKCGYEVVGINYIGDWGTQFGKLITAYKKWGNEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCC
VVKEDPIRELFKLYVQFHEEVKDDEELEEEGRAWFKKLEEGDEEAVELWNWFRHESLKEF
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SRIYELLGVEFTNFQGEAFYNNLMEDFIGILEEHDLLEESEGALVVNLEEEGMPPCLIRK
HHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEE
SDGATIYATRDLTAALYRQNTFGFDKALYVVGPEQSLHFNQFFTVLKKLGYTWVDGMEHV
CCCCEEEEECHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCC
PFGFILKDGKKMSTRKGRVILLEEVLEEAIELAKQNIEEKNPNLKQKEEVAKQVGAGAVI
CEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEE
FHDLKNERMHNIEFSLENMLKFEGETGPYVQYTHARACSILRKESVEFETCTFALKDDHS
EEHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCC
WSVVKLLNKFPQVIEIAFNKNEPSVISKYVLDVAQSFNKYYGNVRILEESEEKDSRLALV
HHHHHHHHHCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
YAVTVVLKEGLRLLGVEAPEEM
HHHHHHHHHCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA