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The map label for this gene is qorA [H]

Identifier: 49184976

GI number: 49184976

Start: 1970527

End: 1971513

Strand: Reverse

Name: qorA [H]

Synonym: BAS1965

Alternate gene names: 49184976

Gene position: 1971513-1970527 (Counterclockwise)

Preceding gene: 49184979

Following gene: 49184975

Centisome position: 37.71

GC content: 39.21

Gene sequence:

>987_bases
ATGAAAGCTATCGTTGTAACGTCGTTCGGAGGATCTGAAGTGATGAAATATACAGATGTAGATATACCGGCTATTTCAGA
AGATCAAGTTTTAATTCGTGTTGTTGCTACGAGTGTAAATTTCGCTGATATTAAATCACGTTATGGCAAAAAAGGAAATA
AAGCGCTACCTTTTATTCTAGGGATAGATGCCGCTGGTATTGTAGAACGTGTCGGTTCTCATGTGAAAAATATTTATCCT
GGACAACGTGTCATTGCTTTCCCTCAAAATGGATCTTACGCTGAATATGTTGTTGCAAATGAAAATCTTACTTTCGTATT
ACCTGATGAAGTCGATTTTCAAACTGCAGCAGCATGCCCTATCGTATCTTTCACAAGCTATAATTTACTCGCAAATGTAG
CAAGGCTTCAACAAGGTGAATCTGTACTCATTCATGCGGCGGCTGGTGGAATTGGCACTACTGCTATTCAACTTGCAAAA
CTATTAGGGGCTGGAACAGTTATAGGTACTGTCGGAAGTGAAGCAAAAAAAGAAATTGCTTTAGATGCCGGTGCTGATTA
TGTAATTGGTCATCAAGATGAAGATTTTGTAGAGAAAGTCAATGAGCTGACAAATGGTGAAGGGGTTGATGTAATTTTAG
ACTCTATTTCTGGAACGGTTTCGGAAAGAAGTTTAAAATGTCTTGCTTATTACGGCCGCCTCATTCATTTCGGTAATGCA
AGTGGTGAAATTGGCAATTTCCAAACGAAAGATTTACATGCAAGTTGCCGCTCTATACTCGGTTTTAGCTTTGGAACTAC
ACGAAAAAAACGTCCTGAACTACTCCAAGAAACTGCAAATGAAGTTTTCCGTTATTTGCGTGACGGACATTTGCAAATCA
AGGCTACGAAATCTTTTCCACTTCAAGATGCAGGGAAAGCACATGAATGGGTCGAAAGTAGAAAAAGTACAGGGAAAGTA
ATACTAACTGTTCAGTCCTCCTCCTGA

Upstream 100 bases:

>100_bases
CATAAGCTTCACTTATAACCTTGCATAACAATTATATAATTTTCCAATTTCTAATGAAGACTTAAAATGATTTATATAGT
CAAATTTAGGAGGATATATG

Downstream 100 bases:

>100_bases
AATGAATACTTGAAACCGAGGTGTCATTCATGGGATCACGAATTATGCATGCTATTATCGCTAACGGTATTGCCGAAAAA
CTATGTATTCAAGATAAAAC

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKAIVVTSFGGSEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFILGIDAAGIVERVGSHVKNIYP
GQRVIAFPQNGSYAEYVVANENLTFVLPDEVDFQTAAACPIVSFTSYNLLANVARLQQGESVLIHAAAGGIGTTAIQLAK
LLGAGTVIGTVGSEAKKEIALDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGHLQIKATKSFPLQDAGKAHEWVESRKSTGKV
ILTVQSSS

Sequences:

>Translated_328_residues
MKAIVVTSFGGSEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFILGIDAAGIVERVGSHVKNIYP
GQRVIAFPQNGSYAEYVVANENLTFVLPDEVDFQTAAACPIVSFTSYNLLANVARLQQGESVLIHAAAGGIGTTAIQLAK
LLGAGTVIGTVGSEAKKEIALDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGHLQIKATKSFPLQDAGKAHEWVESRKSTGKV
ILTVQSSS
>Mature_328_residues
MKAIVVTSFGGSEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFILGIDAAGIVERVGSHVKNIYP
GQRVIAFPQNGSYAEYVVANENLTFVLPDEVDFQTAAACPIVSFTSYNLLANVARLQQGESVLIHAAAGGIGTTAIQLAK
LLGAGTVIGTVGSEAKKEIALDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGHLQIKATKSFPLQDAGKAHEWVESRKSTGKV
ILTVQSSS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=33.4355828220859, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=33.4355828220859, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI22538446, Length=331, Percent_Identity=30.5135951661631, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI22538444, Length=331, Percent_Identity=30.5135951661631, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI194239676, Length=326, Percent_Identity=30.6748466257669, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI24308257, Length=346, Percent_Identity=28.6127167630058, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI18379349, Length=341, Percent_Identity=27.5659824046921, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI47519420, Length=243, Percent_Identity=30.8641975308642, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI67078404, Length=327, Percent_Identity=26.2996941896024, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI41872631, Length=235, Percent_Identity=31.063829787234, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=30.1020408163265, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI28557745, Length=247, Percent_Identity=30.3643724696356, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI67078406, Length=305, Percent_Identity=27.2131147540984, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1790485, Length=323, Percent_Identity=37.1517027863777, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI87082125, Length=365, Percent_Identity=24.9315068493151, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=327, Percent_Identity=30.8868501529052, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71987554, Length=271, Percent_Identity=29.1512915129151, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI212642053, Length=312, Percent_Identity=26.2820512820513, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17536829, Length=293, Percent_Identity=29.0102389078498, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=331, Percent_Identity=33.2326283987915, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319945, Length=267, Percent_Identity=28.4644194756554, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=258, Percent_Identity=25.968992248062, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323493, Length=266, Percent_Identity=27.4436090225564, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=271, Percent_Identity=25.4612546125461, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324195, Length=265, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581345, Length=303, Percent_Identity=29.042904290429, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI19920632, Length=305, Percent_Identity=28.1967213114754, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221330659, Length=305, Percent_Identity=28.1967213114754, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI45550423, Length=157, Percent_Identity=27.3885350318471, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35244; Mature: 35244

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS01162 QOR_ZETA_CRYSTAL ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIVVTSFGGSEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFIL
CCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEE
GIDAAGIVERVGSHVKNIYPGQRVIAFPQNGSYAEYVVANENLTFVLPDEVDFQTAAACP
ECCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCEEEEECCCCCCCHHCCCC
IVSFTSYNLLANVARLQQGESVLIHAAAGGIGTTAIQLAKLLGAGTVIGTVGSEAKKEIA
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCHHHHHEE
LDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
EECCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCC
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGHLQIKATKSFP
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LQDAGKAHEWVESRKSTGKVILTVQSSS
CCCCCHHHHHHHHHCCCCEEEEEEECCC
>Mature Secondary Structure
MKAIVVTSFGGSEVMKYTDVDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFIL
CCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEE
GIDAAGIVERVGSHVKNIYPGQRVIAFPQNGSYAEYVVANENLTFVLPDEVDFQTAAACP
ECCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCEEEEECCCCCCCHHCCCC
IVSFTSYNLLANVARLQQGESVLIHAAAGGIGTTAIQLAKLLGAGTVIGTVGSEAKKEIA
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCHHHHHEE
LDAGADYVIGHQDEDFVEKVNELTNGEGVDVILDSISGTVSERSLKCLAYYGRLIHFGNA
EECCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCC
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGHLQIKATKSFP
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LQDAGKAHEWVESRKSTGKVILTVQSSS
CCCCCHHHHHHHHHCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]