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The map label for this gene is cat1 [H]

Identifier: 49184739

GI number: 49184739

Start: 1745798

End: 1747312

Strand: Direct

Name: cat1 [H]

Synonym: BAS1726

Alternate gene names: 49184739

Gene position: 1745798-1747312 (Clockwise)

Preceding gene: 49184738

Following gene: 49184740

Centisome position: 33.39

GC content: 38.02

Gene sequence:

>1515_bases
ATGGAGAATAATTTGGATAGAATTAGGGATCAACGTCTGAAAGATCGCGTAGTTACACCTGAAGAAGCAGCTTCATGGAT
TGAAAGTGGAATGACTTTAGGCTTAAGTGGGTTTACACGTGCAGGTGATGTGAAAGCAGTCCCATTTGCGCTTGTAAACC
GAGTTAAGAATGATACATCTTTTAAAGTAAATGTTTATACTGGTGCCTCTTTAGGTTCTGATGTAGATAAATTATTTGCG
GAAGCAGGAATTTTAGGGAAAAGATTGCCTTTCCAAGCTGATGCGACTATGCGAAAAGGAATTAATAACGGAGATTTTTT
ATTTGTAGACCAGCACTTATCTCATACAGCAGAGTTACTTCGCGCTGACGTTATGGATGTAGATTTTGCTATTTTGGGAG
CGGTTGCGATTACTGAAGATGGCATGATTATTCCAACAACTTCAATAGGAAATTCTTTAGCGTTTTCTTTAAATGCTAAG
TCTATCATTATTGAAATGAATATGGCCCAATCCGCGCAGCTAGAAGGGCTACATGATTTATATGAACCAGGTAAACAAGG
AGAAAGACTTCCAATTCCACTCGTAAAAACAAATGATCGAATTGGGACGATTGGCATTCCGATTGATGTTGAAAAAGTGA
AAGGGATTGTATTTACGAATCAATTGGATTCACCATCAACAATTGTTCCTCCAGATGAAGAAACTGTTATTATGGCACAG
CATTTAATAGAATTTCTTCGAAAAGAAGTCGAAGTAGGCCGATTAACAAATCGTTTAGCACCGTTACAATCGGGAATTGG
TTCAGTAGCTAATGCAGTTCTTCATGGAATGTTAGATTCGGAGTTTGAAGATTTAGAAGTGTATTCTGAAGTTTTACAGG
ATGCGGTCTTTGATCTTATGGATGCTGGAAAAGTCAATTTTGCTTCATGCTGTTCGATCACACTTTCTGAGGAGAAAATG
CAAAAAGTATTTTCCAACTTTGAAAAATATCGTGACAAATTAATGATGCGCCCGCAAGAGATTTCCAATCATCCTGAAAT
TATTCGCCGCCTCGGATTAATCTCGATTAATACTGCTTTAGAATTAGATATATACGGAAATGTGAACTCTACTCACGTTT
TAGGTACAAAAATGATGAACGGTATCGGTGGTTCTGGTGACTTTGCAAGAAATGCTCGTTTGGCTATCTTTGTTACTAAA
TCGATTGCGAAAGGTGGTAACATTTCAAGTATCGTTCCTTTCGCCTCACATATAGACCATACGGAACATGATGTAGATGT
TATCGTCACTGAGCAAGGATATGCTGACTTAAGAGGACTTGCGCCAAGTGAAAGAGTGGAGCTCATTATTGAGAATTGTG
CACATCTAATGTATCGTGATCAACTACGAGCTTATTATGAGGAAGCGAAAACAAGAGGTGGACAAACTCCTCATATTTTA
GAGAAAGCTTTTTCTTGGCATACGAATTATGCTAAAAATGGAACGATGCTTGAAGAGGTAGTAGAAACTGTATAG

Upstream 100 bases:

>100_bases
CTGTTTTGTCTGAATTTTTGCCATTGTATACTGAAATCCCTATTTGGATACTGTTAAAGTGTAAAATAATTATGAATATT
CATAAGGAGAGGGATTACAT

Downstream 100 bases:

>100_bases
AAATATAAGAATGATTCTTAGAATAATATGCTATAAAGGTTGAAAGAAAAGAACGCCAATTTTCAGGAATGGCGTTTTTT
TCTTTTAAAAAATTATTATC

Product: acetyl-CoA hydrolase/transferase family protein

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVMDVDFAILGAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSAQLEGLHDLYEPGKQGERLPIPLVKTNDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFASHIDHTEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHLMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKNGTMLEEVVETV

Sequences:

>Translated_504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVMDVDFAILGAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSAQLEGLHDLYEPGKQGERLPIPLVKTNDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFASHIDHTEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHLMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKNGTMLEEVVETV
>Mature_504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVMDVDFAILGAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSAQLEGLHDLYEPGKQGERLPIPLVKTNDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFASHIDHTEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHLMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKNGTMLEEVVETV

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=41.5637860082305, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17538151, Length=377, Percent_Identity=25.9946949602122, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319456, Length=518, Percent_Identity=41.3127413127413, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55554; Mature: 55554

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTS
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNVYTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVMDVDFAILGAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSAQLEGLHDL
HHHHHHHHHHHHHHHEEECCCEEEEECCCCCCEEEEECCCEEEEEECCCCHHHHCCHHHH
YEPGKQGERLPIPLVKTNDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCCEEECCCCEEEEECCEEHHHHCCEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFASHIDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCCCHHHHHHHHCCC
TEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHLMYRDQLRAYYEEAKTRGGQTPHIL
CCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKNGTMLEEVVETV
HHHHHHCCCCCCCCHHHHHHHHHC
>Mature Secondary Structure
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTS
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNVYTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVMDVDFAILGAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSAQLEGLHDL
HHHHHHHHHHHHHHHEEECCCEEEEECCCCCCEEEEECCCEEEEEECCCCHHHHCCHHHH
YEPGKQGERLPIPLVKTNDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCCEEECCCCEEEEECCEEHHHHCCEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFASHIDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCCCHHHHHHHHCCC
TEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHLMYRDQLRAYYEEAKTRGGQTPHIL
CCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKNGTMLEEVVETV
HHHHHHCCCCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]