Click here to switch to the map view.

The map label for this gene is pyrH [H]

Identifier: 49184679

GI number: 49184679

Start: 1680330

End: 1681073

Strand: Reverse

Name: pyrH [H]

Synonym: BAS1665

Alternate gene names: 49184679

Gene position: 1681073-1680330 (Counterclockwise)

Preceding gene: 49184689

Following gene: 49184672

Centisome position: 32.15

GC content: 39.38

Gene sequence:

>744_bases
ATGAGGCCATATAAACGTGTCTTAATTAAATTAAGCGGCGGTGCACTTGCCGATCAAACCGGAAATAGCTTTAACTCCAA
AAGATTAGAACATATCGCAAATGAAATTTTATCCATCGTTGATTTAGGTATCGAGGTATCTATCGTCATCGGTGGCGGTA
ACATTTTCAGAGGTCATTTAGCTGAGGAATGGGGAATTGATCGTGTAGAAGCTGATAATATTGGCACATTAGGTACCATC
ATTAATAGCTTAATGCTACGCGGCGTTTTAACAAGCAAAACAAATAAAGAAGTTCGCGTTATGACTTCCATCCCGTTTAA
TGCTGTAGCTGAACCATACATTCGCTTGCGTGCAGTCCATCATTTAGATAACGGTTATATCGTTATTTTTGGAGGCGGTA
ACGGGCAACCGTTCGTTACGACAGACTACCCTAGTGTTCAAAGGGCCATTGAAATGAATAGTGACGCCATATTAGTTGCA
AAACAAGGAGTCGACGGCGTTTTTACTAGTGATCCAAAGCATAATAAATCAGCAAAAATGTATCGAAAACTAAACTATAA
CGATGTTGTTAGGCAAAACATTCAAGTAATGGATCAAGCCGCTTTATTATTGGCCCGTGATTATAATTTACCAGCACACG
TCTTTAACTTTGATGAGCCTGGAGTGATGAGACGAATTTGTTTAGGAGAGCATGTGGGAACGTTGATTAATGATGACGCT
TCATTACTTGTGCATGAGAAATAA

Upstream 100 bases:

>100_bases
AAATTCGTCTTATCTTCTTTTCTTTTTCATTTTCTTAAAAAGGAACAAGGGCATTCGCCTTTGTTCCTTTTTTATTGCGA
TCTATATAGGGGGAATTGTT

Downstream 100 bases:

>100_bases
TTATTTTTCATTTTAAAAGGGTGTCTATAAAAGACACCCTTTTCCCATCAACCTTTATAAATAAAAATCCACCATCCCTG
CAAATTTCTCCTTACAACGC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHLAEEWGIDRVEADNIGTLGTI
INSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVHHLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVA
KQGVDGVFTSDPKHNKSAKMYRKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
SLLVHEK

Sequences:

>Translated_247_residues
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHLAEEWGIDRVEADNIGTLGTI
INSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVHHLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVA
KQGVDGVFTSDPKHNKSAKMYRKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
SLLVHEK
>Mature_247_residues
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHLAEEWGIDRVEADNIGTLGTI
INSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVHHLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVA
KQGVDGVFTSDPKHNKSAKMYRKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
SLLVHEK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=235, Percent_Identity=43.8297872340426, Blast_Score=207, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27265; Mature: 27265

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHL
CCCHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCC
AEEWGIDRVEADNIGTLGTIINSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVH
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHE
HLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVAKQGVDGVFTSDPKHNKSAKM
ECCCCEEEEEECCCCCCEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHH
YRKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCC
SLLVHEK
EEEEECC
>Mature Secondary Structure
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHL
CCCHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCC
AEEWGIDRVEADNIGTLGTIINSLMLRGVLTSKTNKEVRVMTSIPFNAVAEPYIRLRAVH
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHE
HLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVAKQGVDGVFTSDPKHNKSAKM
ECCCCEEEEEECCCCCCEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHH
YRKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMRRICLGEHVGTLINDDA
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCC
SLLVHEK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA