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The map label for this gene is phoR [H]

Identifier: 49184388

GI number: 49184388

Start: 1400160

End: 1401971

Strand: Reverse

Name: phoR [H]

Synonym: BAS1371

Alternate gene names: 49184388

Gene position: 1401971-1400160 (Counterclockwise)

Preceding gene: 49184389

Following gene: 49184387

Centisome position: 26.81

GC content: 31.84

Gene sequence:

>1812_bases
GTGAAAAACAGAAGTATCGTCTTTAAACTATTTCTATTAACATCAACATTATTTACAATCATATTCCTCCTTTTTTTCCT
AGGGCAATCTCTATTTTTAGAAAAATTTTATATCAATAAAAAAGTAAAAACCGTTCAAACTGCTTTTGAAAAATTCGTAG
CTAATTATGAAAAAAGCGAAAAAAATCCTGAGGAAGTTAGAAAATTAAAACAAGAATTCCATGATAAAACAAATGCTGAC
ATGCAATTTTTAAATACGAATGGCATTATTAAAAGCGACAACAATTACTACATTGAAGTATTTAATCCTAAAAATCATGA
AACATATTCCATTCCGCTTAATAATCTTTTAACACCCGAAGAATATAAGAAATTCGAAAACTTAGGATTGAAAAAAGACG
ATGTGATAAACGTCGTCGGTTTGCTACAAAACAACACAATAACACCAATAAAATTGACAACAAATTATAATCGTTGGCAA
AACGAATATACCAATTCAGATTTTTCATCTATTAGTGGTAACCCTTCTAAAAATAGACTTACAAACCGATACAAAACTGT
TACTCAAATTGAGTTTACTGGTACTATATCTAAGCTACAGCTTCCATCGAAAGCCGAGGTTCGTCTTGCAAATGATATTG
AAACATTACAAGCCGTTCAATATTTTGCAGAGCTTATTAGAAATGGCACTGCTAACTCGCAGCAATTAAACACTTATATA
ATAGATAGCGGGGAGAATATAAAGAATAGTATCTTTGTAAAACCTATTATAAAAAATGGAGAGATTACAGAATATGCTTT
TGCGATAGCATCCTTACAACCTGTTAATGAAGCGATGCTCGTTTTGAAAGATTATTATGTTTATGCCTTAATCATCGTAT
TTCTCGTAATTATTTTGTTATCCTTCTACTACTCAAAAATCATTGTGAAACCATTAATTAAAATTAATCGCGTTACAAAG
AAAATGGCCAATTTTGATTTTAGCGAGAAATTACCTGTAACAGCAGACGATGAAATTGGCGGACTTTCCGGTAGTATTAA
TACGTTATCTGTAAACTTAAAAGACCGAATCGATCGGTTAAATGTTGCAAACACAAAACTACAACAAGATATTGAACGTG
AACGTCAATTAGAGAAAACGCGAAAAGAATTCATTTCTGGTGTATCACACGAATTAAAAACACCACTCAGTGTAATTAGA
AGTTTCGCTGAAGGAATTAAAGATGGTGTTAGTAAAGATACGACGTATTACACAGATGTTATTTTAGAAGAAACAGAAAA
TATGAACAGACTTATTGTTGAAATGTTAGAATTAGCAAAATTAGAATCAGGTACGTACAAACTAGATATGACGACATTCT
CCATCGGTGAATTAATTCAACAAGTCTATACAAAGTTATTATTTAGCATGGAAGAAAAGCATTTACAAGTGAACATAGAT
GTAAACTCGTCTATATTTGTGAAAGCGAATCGTAGTCGTATTGAGCAAGTGGTTGTGAACTTACTTAGCAATGCGATTCG
CTATACGCCAGAAGGAGAAAAAATACAAGTCTCCGTTATAACAATGGAAGATACAGTAAAAATCGAAATCGAAAACACAG
GAAATCCTATCCCAGAAGAAAGTCTTGAAAAAATTTGGGATCGCTTCTACCGTTTAGATGCATCTCGTAGCCGTCATACT
GGTGGTACTGGTCTCGGTTTATCTATTGTTAAAAATATTTTAGACCTCCACCATGCCGAGTATGGTGTATATAATACGAC
TAATAGTGTTGTATTCTACTTTAATTTACAAAAAGTAAAAGAAGTCAAATAA

Upstream 100 bases:

>100_bases
AAAACTACTTTCGGATGAGACAGATTTTCTCCTCTACTTTTTTGTAACGTTTGTTATAATAAAGTAATCATTTACAGTAT
TTCTCACAAGAGGTGACGCA

Downstream 100 bases:

>100_bases
TTTGTCTTAATTTCACTAGGAGTTCACATGAAATTCACACTCTCCCTTTATAGTTAGAAACAAGTTAATCCTTTCCTTTA
CACATATAAAAGAGGAGAGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSEKNPEEVRKLKQEFHDKTNAD
MQFLNTNGIIKSDNNYYIEVFNPKNHETYSIPLNNLLTPEEYKKFENLGLKKDDVINVVGLLQNNTITPIKLTTNYNRWQ
NEYTNSDFSSISGNPSKNRLTNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
IDSGENIKNSIFVKPIIKNGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTK
KMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIR
SFAEGIKDGVSKDTTYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
VNSSIFVKANRSRIEQVVVNLLSNAIRYTPEGEKIQVSVITMEDTVKIEIENTGNPIPEESLEKIWDRFYRLDASRSRHT
GGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK

Sequences:

>Translated_603_residues
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSEKNPEEVRKLKQEFHDKTNAD
MQFLNTNGIIKSDNNYYIEVFNPKNHETYSIPLNNLLTPEEYKKFENLGLKKDDVINVVGLLQNNTITPIKLTTNYNRWQ
NEYTNSDFSSISGNPSKNRLTNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
IDSGENIKNSIFVKPIIKNGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTK
KMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIR
SFAEGIKDGVSKDTTYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
VNSSIFVKANRSRIEQVVVNLLSNAIRYTPEGEKIQVSVITMEDTVKIEIENTGNPIPEESLEKIWDRFYRLDASRSRHT
GGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK
>Mature_603_residues
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSEKNPEEVRKLKQEFHDKTNAD
MQFLNTNGIIKSDNNYYIEVFNPKNHETYSIPLNNLLTPEEYKKFENLGLKKDDVINVVGLLQNNTITPIKLTTNYNRWQ
NEYTNSDFSSISGNPSKNRLTNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
IDSGENIKNSIFVKPIIKNGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTK
KMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIR
SFAEGIKDGVSKDTTYYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
VNSSIFVKANRSRIEQVVVNLLSNAIRYTPEGEKIQVSVITMEDTVKIEIENTGNPIPEESLEKIWDRFYRLDASRSRHT
GGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVKEVK

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=298, Percent_Identity=27.5167785234899, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=29.0178571428571, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=27.3885350318471, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=26.6409266409266, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788279, Length=376, Percent_Identity=27.9255319148936, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790861, Length=231, Percent_Identity=29.8701298701299, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI87082128, Length=325, Percent_Identity=23.0769230769231, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788713, Length=218, Percent_Identity=29.3577981651376, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=27.3542600896861, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=22.9508196721311, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=28.6995515695067, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790551, Length=308, Percent_Identity=25, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=28.6363636363636, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790346, Length=204, Percent_Identity=27.9411764705882, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081816, Length=315, Percent_Identity=23.1746031746032, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=275, Percent_Identity=26.9090909090909, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI48994928, Length=213, Percent_Identity=25.8215962441315, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=297, Percent_Identity=24.9158249158249, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789403, Length=303, Percent_Identity=23.4323432343234, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69276; Mature: 69276

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
KNPEEVRKLKQEFHDKTNADMQFLNTNGIIKSDNNYYIEVFNPKNHETYSIPLNNLLTPE
CCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCEEEEEECCCCCCEEECCCCCCCCHH
EYKKFENLGLKKDDVINVVGLLQNNTITPIKLTTNYNRWQNEYTNSDFSSISGNPSKNRL
HHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCCCHHHCCCCCCHHHH
TNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
HHHHHEEEEEEEECCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
IDSGENIKNSIFVKPIIKNGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILL
EECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SFYYSKIIVKPLIKINRVTKKMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHC
NVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIRSFAEGIKDGVSKDTTYYTDV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
HHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
VNSSIFVKANRSRIEQVVVNLLSNAIRYTPEGEKIQVSVITMEDTVKIEIENTGNPIPEE
CCCEEEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECEEEEEECCCCCCCCHH
SLEKIWDRFYRLDASRSRHTGGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVK
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHH
EVK
CCC
>Mature Secondary Structure
MKNRSIVFKLFLLTSTLFTIIFLLFFLGQSLFLEKFYINKKVKTVQTAFEKFVANYEKSE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
KNPEEVRKLKQEFHDKTNADMQFLNTNGIIKSDNNYYIEVFNPKNHETYSIPLNNLLTPE
CCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCEEEEEECCCCCCEEECCCCCCCCHH
EYKKFENLGLKKDDVINVVGLLQNNTITPIKLTTNYNRWQNEYTNSDFSSISGNPSKNRL
HHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCCCHHHCCCCCCHHHH
TNRYKTVTQIEFTGTISKLQLPSKAEVRLANDIETLQAVQYFAELIRNGTANSQQLNTYI
HHHHHEEEEEEEECCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
IDSGENIKNSIFVKPIIKNGEITEYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILL
EECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SFYYSKIIVKPLIKINRVTKKMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHC
NVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIRSFAEGIKDGVSKDTTYYTDV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVNID
HHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
VNSSIFVKANRSRIEQVVVNLLSNAIRYTPEGEKIQVSVITMEDTVKIEIENTGNPIPEE
CCCEEEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEECEEEEEECCCCCCCCHH
SLEKIWDRFYRLDASRSRHTGGTGLGLSIVKNILDLHHAEYGVYNTTNSVVFYFNLQKVK
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEHHHHH
EVK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]