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The map label for this gene is ygbD [C]

Identifier: 49184188

GI number: 49184188

Start: 1215119

End: 1216453

Strand: Direct

Name: ygbD [C]

Synonym: BAS1170

Alternate gene names: 49184188

Gene position: 1215119-1216453 (Clockwise)

Preceding gene: 49184186

Following gene: 49184189

Centisome position: 23.24

GC content: 38.43

Gene sequence:

>1335_bases
GTGAACTATGTCATTATTGGCGGAGATGCAGCTGGTATGAGTGCAGCTATGCAAATTGTTAGAAACGATGAAAATGCAAA
TGTTGTGACGCTAGAAAAAGGTGAAATTTATTCGTATGCGCAGTGTGGGTTACCGTATGTCATTAGTGGTGCTATCGCTT
CAACGGAAAAGTTAATCGCGCGTAATGTAAAGACGTTTCGTGATAAATACGGAATTGATGCGAAAGTACGACATGAAGTA
ACGAAAGTAGATACGGAAAAGAAAATAGTATACGCAGAGCATACGAAGACGAAAGATGTTTTTGAATTTTCGTATGACCG
TTTATTAATTGCGACCGGAGTACGTCCTGTTATGCCAGAATGGGAAGGGCGAGATTTACAAGGCGTTCATCTTTTAAAAA
CAATCCCAGATGCTGAGCGCATATTAAAAACACTAGAAACGAATAAAGTTGAGGATGTAACTATTATTGGCGGTGGTGCA
ATTGGGCTGGAAATGGCAGAAACATTCGTCGAACTTGGTAAGAAAGTAAGAATGATTGAGCGAAATGATCATATCGGTAC
GATTTATGATGGGGATATGGCGGAGTATATATATAAAGAGGCAGATAAACATCATATTGAAATTTTAACGAATGAAAATG
TAAAAGCGTTTAAAGGGAATGAACGAGTAGAAGCAGTTGAAACGGATAAAGGTACGTATAAAGCGGATCTTGTTTTAGTA
TCTGTCGGAGTGAAGCCGAATACTGATTTTCTTGAAGGAACGAATATACGTACAAATCATAAAGGGGCAATCGAGGTAAA
TGCATATATGCAAACGAATGTGCAAGACGTATATGCAGCTGGTGATTGTGCGACACATTATCACGTGATAAAAGAAATTC
ATGATCATATTCCAATTGGAACAACTGCAAATAAACAAGGGCGACTTGCTGGACTGAATATGCTAGATAAACGAAGAGCT
TTTAAAGGAACGTTAGGTACAGGCATTATTAAATTTATGAATTTGACGCTCGCAAGAACAGGCTTAAATGAAAAAGAAGC
AAAAGGACTACATATCCCGTATAAAACAGTCAAAGTAGATTCGACTAATATGGCGGGCTATTATCCAAATGCGAAACCAC
TTTACTTGAAATTACTATACCGTTCTGACACGAAACAATTATTAGGTGGACAAGTAATTGGAGAAGAAGGTGTAGATAAA
CGGATTGATGTAATCGCAATGGCACTCTTCAATAAAATGAGCATTCACGATTTAGAAGATGTGGACTTAAGTTATGCACC
ACCATATAACAGCGTTTGGGATCCAATTCAGCAAGCGGCAAGGCGAGCGGAATAG

Upstream 100 bases:

>100_bases
AATTTGAAGATGAAATTCTCTTTCTTTACAATAGAAGTAGGTGTTATTTCTATAAAATATGGAAAACGTAAAGAGTATGT
AAAAAAGAAGGAGTGGTAAA

Downstream 100 bases:

>100_bases
CACTTTTTAAGTGCTATTTTTTTCGTTAAAGGGTAATCATCATTTTTGTAGAATGAAGAGGGTTGGGAAATAGTTACATA
TAGGGAAGGGGATCATTAAA

Product: pyridine nucleotide-disulfide oxidoreductase, class I

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEV
TKVDTEKKIVYAEHTKTKDVFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGA
IGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLV
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMLDKRRA
FKGTLGTGIIKFMNLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDK
RIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE

Sequences:

>Translated_444_residues
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEV
TKVDTEKKIVYAEHTKTKDVFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGA
IGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLV
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMLDKRRA
FKGTLGTGIIKFMNLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDK
RIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE
>Mature_444_residues
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEV
TKVDTEKKIVYAEHTKTKDVFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGA
IGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLV
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMLDKRRA
FKGTLGTGIIKFMNLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDK
RIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=322, Percent_Identity=27.9503105590062, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI65787454, Length=322, Percent_Identity=27.9503105590062, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI21389617, Length=322, Percent_Identity=27.9503105590062, Blast_Score=115, Evalue=8e-26,
Organism=Escherichia coli, GI1789065, Length=285, Percent_Identity=23.5087719298246, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87082354, Length=318, Percent_Identity=25.4716981132075, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789765, Length=340, Percent_Identity=23.2352941176471, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786307, Length=310, Percent_Identity=24.5161290322581, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789915, Length=316, Percent_Identity=24.6835443037975, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=249, Percent_Identity=27.3092369477912, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32565766, Length=139, Percent_Identity=30.9352517985612, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24585130, Length=322, Percent_Identity=26.7080745341615, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24639257, Length=323, Percent_Identity=25.077399380805, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281359715, Length=323, Percent_Identity=25.077399380805, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281359713, Length=323, Percent_Identity=25.077399380805, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24639250, Length=323, Percent_Identity=25.077399380805, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI18543267, Length=323, Percent_Identity=25.077399380805, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24639252, Length=323, Percent_Identity=25.077399380805, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24581020, Length=361, Percent_Identity=25.207756232687, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28573993, Length=361, Percent_Identity=25.207756232687, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 49483; Mature: 49483

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIA
CCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEHHHCCCCEEEECHHHHHHHHHH
RNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVFEFSYDRLLIATGVRPVMPE
HHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCEEEEECCCCCCCCC
WEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIE
CCCCCCCCEEHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEE
RNDHIGTIYDGDMAEYIYKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLV
CCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCEEEECCCCCEEEEECCCCCEEEEEEEE
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIG
EECCCCCCCCCCCCCEEECCCCEEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHCCCCC
TTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMNLTLARTGLNEKEAKGLHIPYKTVKVD
CCCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEC
STNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDLED
CCCCCCCCCCCCEEEEEEEECCCHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
VDLSYAPPYNSVWDPIQQAARRAE
CCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIA
CCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEHHHCCCCEEEECHHHHHHHHHH
RNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVFEFSYDRLLIATGVRPVMPE
HHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCEEEEECCCCCCCCC
WEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIE
CCCCCCCCEEHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEE
RNDHIGTIYDGDMAEYIYKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLV
CCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCEEEECCCCCEEEEECCCCCEEEEEEEE
SVGVKPNTDFLEGTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIG
EECCCCCCCCCCCCCEEECCCCEEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHCCCCC
TTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMNLTLARTGLNEKEAKGLHIPYKTVKVD
CCCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEC
STNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDLED
CCCCCCCCCCCCEEEEEEEECCCHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
VDLSYAPPYNSVWDPIQQAARRAE
CCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA