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The map label for this gene is yvmA [H]

Identifier: 49183731

GI number: 49183731

Start: 767354

End: 768535

Strand: Reverse

Name: yvmA [H]

Synonym: BAS0707

Alternate gene names: 49183731

Gene position: 768535-767354 (Counterclockwise)

Preceding gene: 49183735

Following gene: 49183726

Centisome position: 14.7

GC content: 34.01

Gene sequence:

>1182_bases
ATGAAAAAATCTAAACTAACTTTCATTTTATATGTTGTCTGTATGAGTGCCCTACTCGGTTCCTTCGCTCAAAATATTTA
CACACCTATCTTACCGATGATTCAAAATTCTTTTCACACTTCTCTTTATCTTGTAAATGTAACAGTTTCACTTTTCACAT
TTGTTCTTGCGATTATGCAGCTCATATATGGACCTTTAATTGATACAAAAGGAAGAAAGTCTGTCCTTATCCCTAGTTTA
ATTATTAGTACAATTGGTTCAATAGGATGTGCTTTTTCGGCAAACATTTATTTATTTCTCTTTTTTAGAGCTGTTCAAGC
TATAGGAATAGCGGCTATACCTGTAGTCGCAGCAACGATTATTGGCGATTTATTTGAAGGAAAAGAACGAGGAGAAGCAA
TGAGCCTTTATCAAATGTTACTTGCTCTTGCACCTGCGATTGGCCCCCTCATTGGTGGTTATCTCGGTAGTATAAACGGC
CATGTATCCGTATTTCTCTTTTTATCTATACTTGGCATTCTCTTATTAACGATAAACATTTCACTACTTCCAGAAACAAA
ACCAACTGTAAGTCAGCAACCGCAATCAAAAAAGAATCACTGGTTTATCTTAAAAAATAAAACTGGATTTTCTATTACTC
TTATTGGCTTCATTCAATTTTGTATTTACTTTTGTTTCCTCGTTTTTTTACCGAGCATTTCAACAAATTTATTTCACTTA
ACTGCAAGTGAAATTGGTCTTATGTTTGTACCTATGTCCCTTTCTATTATGTTAGGAAGTTATTGCTTCAAACTTTTGCA
AAAACGCTTCACAACAAAACAAGCTTTATTCATTACAAGTTTCTTCAATATTATATGTGTCACTTTATTTTCTTTCACAT
ATAGCATCAATATTCCATTCATCATTATCGTTACATCTTTGTACGGTTTTAGCATGGGACTTTCTATGCCAACCCACACT
ACTTTATTAACGGAGGAATTCGTACAAGAACGCGCAACCGCTATCGGTATGTATAACTTCATCCGCTATCTCGGTATGGG
AACAGTACCACTTGTAGGTGGATTTCTTGTATTTAATCAAAATTACTTTTGGATTTTCTTCTTAGGAGCAATTATGTTTC
TACTCATAATCTTATATGCGATGAAAATGCTACGCTTCCCTACCACACAAAAAGTAAAATAG

Upstream 100 bases:

>100_bases
TATACCATTTTAAAACCATTTTTTCATCTTTACAAGTGAGAAAATCATGTTAAAATAAATTTAGTTTCCAGGGAAACAAA
AACACAAGGAGGTTAACAAG

Downstream 100 bases:

>100_bases
AGCCCCCAAAAGGTCGGCTCTATTTTAAGCTCTTTGATCCGCAACGATATGAATATCAATATACTTCGTTTCTCTCATAA
TTTCATTTACAATCGAACCT

Product: major facilitator family transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQLIYGPLIDTKGRKSVLIPSL
IISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVAATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSING
HVSVFLFLSILGILLLTINISLLPETKPTVSQQPQSKKNHWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSISTNLFHL
TASEIGLMFVPMSLSIMLGSYCFKLLQKRFTTKQALFITSFFNIICVTLFSFTYSINIPFIIIVTSLYGFSMGLSMPTHT
TLLTEEFVQERATAIGMYNFIRYLGMGTVPLVGGFLVFNQNYFWIFFLGAIMFLLIILYAMKMLRFPTTQKVK

Sequences:

>Translated_393_residues
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQLIYGPLIDTKGRKSVLIPSL
IISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVAATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSING
HVSVFLFLSILGILLLTINISLLPETKPTVSQQPQSKKNHWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSISTNLFHL
TASEIGLMFVPMSLSIMLGSYCFKLLQKRFTTKQALFITSFFNIICVTLFSFTYSINIPFIIIVTSLYGFSMGLSMPTHT
TLLTEEFVQERATAIGMYNFIRYLGMGTVPLVGGFLVFNQNYFWIFFLGAIMFLLIILYAMKMLRFPTTQKVK
>Mature_393_residues
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQLIYGPLIDTKGRKSVLIPSL
IISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVAATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSING
HVSVFLFLSILGILLLTINISLLPETKPTVSQQPQSKKNHWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSISTNLFHL
TASEIGLMFVPMSLSIMLGSYCFKLLQKRFTTKQALFITSFFNIICVTLFSFTYSINIPFIIIVTSLYGFSMGLSMPTHT
TLLTEEFVQERATAIGMYNFIRYLGMGTVPLVGGFLVFNQNYFWIFFLGAIMFLLIILYAMKMLRFPTTQKVK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=280, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790146, Length=183, Percent_Identity=25.6830601092896, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082312, Length=360, Percent_Identity=22.5, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788509, Length=246, Percent_Identity=26.0162601626016, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322071, Length=205, Percent_Identity=31.219512195122, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324264, Length=180, Percent_Identity=28.8888888888889, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319517, Length=189, Percent_Identity=29.1005291005291, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319657, Length=186, Percent_Identity=30.1075268817204, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322070, Length=269, Percent_Identity=26.0223048327138, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325414, Length=415, Percent_Identity=20.4819277108434, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321577, Length=418, Percent_Identity=20.0956937799043, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43851; Mature: 43851

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEHHHHHHHHHHHHHHH
LIYGPLIDTKGRKSVLIPSLIISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVAATI
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSINGHVSVFLFLSILGILLLTINI
HHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SLLPETKPTVSQQPQSKKNHWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSISTNLFHL
EECCCCCCCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEE
TASEIGLMFVPMSLSIMLGSYCFKLLQKRFTTKQALFITSFFNIICVTLFSFTYSINIPF
EHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
IIIVTSLYGFSMGLSMPTHTTLLTEEFVQERATAIGMYNFIRYLGMGTVPLVGGFLVFNQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEC
NYFWIFFLGAIMFLLIILYAMKMLRFPTTQKVK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEHHHHHHHHHHHHHHH
LIYGPLIDTKGRKSVLIPSLIISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVAATI
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSINGHVSVFLFLSILGILLLTINI
HHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SLLPETKPTVSQQPQSKKNHWFILKNKTGFSITLIGFIQFCIYFCFLVFLPSISTNLFHL
EECCCCCCCCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEE
TASEIGLMFVPMSLSIMLGSYCFKLLQKRFTTKQALFITSFFNIICVTLFSFTYSINIPF
EHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
IIIVTSLYGFSMGLSMPTHTTLLTEEFVQERATAIGMYNFIRYLGMGTVPLVGGFLVFNQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEC
NYFWIFFLGAIMFLLIILYAMKMLRFPTTQKVK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]