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The map label for this gene is qoxA

Identifier: 49183694

GI number: 49183694

Start: 722125

End: 723000

Strand: Reverse

Name: qoxA

Synonym: BAS0669

Alternate gene names: 49183694

Gene position: 723000-722125 (Counterclockwise)

Preceding gene: 49183695

Following gene: 49183693

Centisome position: 13.83

GC content: 37.56

Gene sequence:

>876_bases
GTGCAACTAAAGAAAGCGTTTTGGAAGTTGGCTTCGCTTCTTCCGTTATCATTACTTCTGTTCCTCGGTGGCTGTGATAA
AAAACTCGCAGTATTAAATCCGCAAGGACCTGTTGCAAAAGCACAGTATGATTTAATTGTTTGGTCATTCTTGCTTATGT
CATTAATTATCGCAATTGTATTCATCTTGTTTACAGTCATCTTGATTCGTTATCGTGAAAAACCAGAGAATATGGACTAT
GAGCCACCTGAACAACACGGTAACACATTATTAGAAATCATTTGGACGCTTGTTCCTGTTATTATCGTTATCGCATTATC
GATTCCAACAGTAAAAGCAACTTATGCTTCGGAAGAGGTTCCGAAAGAGTCCAAACATATTAAACCAGTGGAGATTTATG
TTACATCTGCAAACTGGAAATGGTTATTCAGTTACCCAGAGGAAAAAATTGAAACCGTTAACTATTTAAACATCCCAGCT
GGTGTACCAATTCAATTCAAACTGACTTCTGTCGGCCCAATGAATGCTTTCTGGGTACCAGAACTTGGTGGTATGAAGTA
CACAATGGATGGCATGATTATGGACCTTTATTTACAAGCTGATAAGCCAGGTTCTTACCTAGGCCGTAGCGCGAACTTCT
CTGGTGAAGGATTTACTCACATGGAGTTCGAAGTTGAAGCAAAAACTAAAGAGAAATATGACAAGTGGGTTAAAGAAGTA
CAACAAACTGCTCCTAAACTAACAGAAGATAAGTACAACGAAATTGTTAAACCTGGTGTAGTTGGTCGTATGACATTCTC
TAGCCATCACTTAAGTTATGTAGATCCAAAATCACTTGAATATTGTGATTACAACTACTACAAAAACAAAAAATAA

Upstream 100 bases:

>100_bases
TTTTAACAATATCTCAAAAACTATTGCCTTCTATAAATTAATAGGTTTATATTGTTTTATTGGCATAGTTTCAATCCAAG
GAGAAAGGAGATTTTCAATC

Downstream 100 bases:

>100_bases
TAGCTATAATTCCAACAGATTGGAGTGAACACAGTGAAGCTTGATGAATTCTTTGTCACAGGTGACCCGATTATTTACGG
TGCAGACGCTTCTATCGTTC

Product: quinol oxidase subunit II

Products: ferricytochrome c; H2O

Alternate protein names: Cytochrome aa(3) subunit 2; Quinol oxidase polypeptide II

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIVFILFTVILIRYREKPENMDY
EPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEVPKESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPA
GVPIQFKLTSVGPMNAFWVPELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK

Sequences:

>Translated_291_residues
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIVFILFTVILIRYREKPENMDY
EPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEVPKESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPA
GVPIQFKLTSVGPMNAFWVPELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK
>Mature_291_residues
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIVFILFTVILIRYREKPENMDY
EPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEVPKESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPA
GVPIQFKLTSVGPMNAFWVPELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK

Specific function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family

Homologues:

Organism=Escherichia coli, GI1786635, Length=251, Percent_Identity=37.8486055776892, Blast_Score=164, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6226540, Length=216, Percent_Identity=22.2222222222222, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QOX2_BACAN (Q81V01)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_843230.1
- RefSeq:   YP_017333.1
- RefSeq:   YP_026946.1
- ProteinModelPortal:   Q81V01
- SMR:   Q81V01
- EnsemblBacteria:   EBBACT00000008709
- EnsemblBacteria:   EBBACT00000018162
- EnsemblBacteria:   EBBACT00000022955
- GeneID:   1088154
- GeneID:   2816287
- GeneID:   2851329
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_0703
- KEGG:   bar:GBAA_0703
- KEGG:   bat:BAS0669
- TIGR:   BA_0703
- TIGR:   GBAA_0703
- GeneTree:   EBGT00050000001583
- HOGENOM:   HBG313936
- OMA:   PCLIIIA
- ProtClustDB:   CLSK915927
- BioCyc:   BANT260799:BAS0669-MONOMER
- BioCyc:   BANT261594:GBAA0703-MONOMER
- InterPro:   IPR012141
- InterPro:   IPR008972
- InterPro:   IPR006332
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- Gene3D:   G3DSA:1.10.287.90
- Gene3D:   G3DSA:2.60.40.420
- PANTHER:   PTHR22888
- PIRSF:   PIRSF000292
- PRINTS:   PR01166
- TIGRFAMs:   TIGR01432

Pfam domain/function: PF02790 COX2_TM; SSF49503 Cupredoxin; SSF81464 Cyt_c_oxidase_II-like_TM

EC number: 1.9.3.1

Molecular weight: Translated: 33336; Mature: 33336

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50857 COX2_CUA; PS50999 COX2_TM; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfc4e658)-; HASH(0x103ac7c4)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIV
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
FILFTVILIRYREKPENMDYEPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHC
PKESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPAGVPIQFKLTSVGPMNAFWVP
CCHHCCCCEEEEEEECCCCEEEECCCHHHHCCCEEEECCCCCCEEEEEECCCCCCEEECC
ELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
CCCCCEEECCCEEEEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHH
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK
HHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIV
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
FILFTVILIRYREKPENMDYEPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHC
PKESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPAGVPIQFKLTSVGPMNAFWVP
CCHHCCCCEEEEEEECCCCEEEECCCHHHHCCCEEEECCCCCCEEEEEECCCCCCEEECC
ELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
CCCCCEEECCCEEEEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHH
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK
HHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrocytochrome c; O2

Specific reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629