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The map label for this gene is ywoG [H]

Identifier: 49183665

GI number: 49183665

Start: 691873

End: 693045

Strand: Reverse

Name: ywoG [H]

Synonym: BAS0640

Alternate gene names: 49183665

Gene position: 693045-691873 (Counterclockwise)

Preceding gene: 49183672

Following gene: 49183653

Centisome position: 13.25

GC content: 36.74

Gene sequence:

>1173_bases
TTGAAATATTTTATTTACTTTATTGTTATCGTAGCGTTTCTAGATACATTTTCACAATTACCTATTATGAGTACGTTCGC
TCAAAGTCTTGGAGGATCCCCTCTTATTATTGGGCTAGTTGTCGGCATGTACTCATTCGCTAATATGATCGGTAATATTA
TTGCTGGCGCTGCTGTCGATAAATTTGGTGCAAAAAAAATACTTTATATAAGCATGGGACTTACGAGTTTCATAGTCTTG
TTATACACTGTTGTTCAAAGTGGTGAACAACTATTAGTTGTGCGCTTTATGCATGGCTTTAGTGACGGATTTTTAATTCC
CGCTGCCTTTACGTTTTTATCAAAACAAACAAATGCAGCAAGACAAGGTAAGGCAATGGCTCTATCTGGTGCTGCTGTTG
GAACAGCGGCAATTGTAGGACCTGCTTTTAGCGGTATTATGAAAGCAACTGCTGGTATAGAGTGGGTGTTCATTACCATT
TCTATTTTAATGGTTCTTGGTACAATCGTATCTCTATTCTTCTTACCAAATAACGTATCAAGAAAAGATACTTCAAGAAC
ACAAATGATGAACAAAGAAGATATGTTTGAACTATTGAAATCAGAACCGTTATTACAGGCGTATATTGGTGCTTTCACAC
TCATGTTTTCACAAGGAATTGTCACTTACATGTTACCAGTGAAAGTTGAGGCATTGGCACTTAAAGCATCTACAACAGGC
ATGATGTTAAGTGCATTCGGCATTACCGCTATCCTCTTCTTCTTACTACCAACAAATCGTATTTATGATCGATTTAATCG
TTCAAAACTAATGCTAATCGGTATTGCAGTAATGGCATTAGCATTATCTTTACTTGGATTATTCGCAACAAAAGGCATGC
TCTTTATCGTTATGATGATTTATGGCATTGGATTCGCTATCCTTTTCCCATCGATAAATGCATTACTTGTTGAAAATACG
ACAAATGATAAACGTGGAAAAGCATTCGGATTGTTTTATGCTTTCTTCTCATTAGGAGTTGTTGCTGGATCCTTTACAGT
TGGAGCAATCGGGGCATCCCCTAGCGTCAGCTTCGTTATTGGAACTGCATTCTTATTAACATTCGCTGGAATGATTTATG
TAAGAAGCAAGGTAAAAGGTAGAGACAAAGTAAAAAAGACAATGATAGGATAA

Upstream 100 bases:

>100_bases
TATTTTGTCACTTTGTACTTTTTTCCACATCTGTTAATTCAATTTCATTGCGGTTGAAATTCGCATTATGCCATAATAGC
ATAGGAGAGGTGAATATCGC

Downstream 100 bases:

>100_bases
TTCCATCATTGTCTTTTTTTTAATGATAAACTCCTATTCAACTTTTAACTTTCAACAAGCCGTATTTAATAAACAATATG
GCATTATATTTTTCATAGAG

Product: multidrug resistance protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVDKFGAKKILYISMGLTSFIVL
LYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAARQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITI
SILMVLGTIVSLFFLPNNVSRKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
MMLSAFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMIYGIGFAILFPSINALLVENT
TNDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVIGTAFLLTFAGMIYVRSKVKGRDKVKKTMIG

Sequences:

>Translated_390_residues
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVDKFGAKKILYISMGLTSFIVL
LYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAARQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITI
SILMVLGTIVSLFFLPNNVSRKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
MMLSAFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMIYGIGFAILFPSINALLVENT
TNDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVIGTAFLLTFAGMIYVRSKVKGRDKVKKTMIG
>Mature_390_residues
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVDKFGAKKILYISMGLTSFIVL
LYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAARQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITI
SILMVLGTIVSLFFLPNNVSRKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
MMLSAFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMIYGIGFAILFPSINALLVENT
TNDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVIGTAFLLTFAGMIYVRSKVKGRDKVKKTMIG

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42057; Mature: 42057

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS00018 EF_HAND_1 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVD
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFGAKKILYISMGLTSFIVLLYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAA
HCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCCHHHHHHHHHHHHCCHH
RQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITISILMVLGTIVSLFFLPNNVS
HCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
RKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
CCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHEEEHHHEEEHHEEECCCCH
MMLSAFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMI
HHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGIGFAILFPSINALLVENTTNDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVI
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
GTAFLLTFAGMIYVRSKVKGRDKVKKTMIG
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MKYFIYFIVIVAFLDTFSQLPIMSTFAQSLGGSPLIIGLVVGMYSFANMIGNIIAGAAVD
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFGAKKILYISMGLTSFIVLLYTVVQSGEQLLVVRFMHGFSDGFLIPAAFTFLSKQTNAA
HCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCCHHHHHHHHHHHHCCHH
RQGKAMALSGAAVGTAAIVGPAFSGIMKATAGIEWVFITISILMVLGTIVSLFFLPNNVS
HCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
RKDTSRTQMMNKEDMFELLKSEPLLQAYIGAFTLMFSQGIVTYMLPVKVEALALKASTTG
CCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHEEEHHHEEEHHEEECCCCH
MMLSAFGITAILFFLLPTNRIYDRFNRSKLMLIGIAVMALALSLLGLFATKGMLFIVMMI
HHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGIGFAILFPSINALLVENTTNDKRGKAFGLFYAFFSLGVVAGSFTVGAIGASPSVSFVI
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
GTAFLLTFAGMIYVRSKVKGRDKVKKTMIG
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]