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The map label for this gene is benK [H]

Identifier: 49183377

GI number: 49183377

Start: 373321

End: 374631

Strand: Reverse

Name: benK [H]

Synonym: BAS0349

Alternate gene names: 49183377

Gene position: 374631-373321 (Counterclockwise)

Preceding gene: 49183378

Following gene: 49183374

Centisome position: 7.16

GC content: 37.38

Gene sequence:

>1311_bases
GTGAATACTATGCAACCTTCAGCTCCACCTCATCTAGAATCTACAAAAACTATCTTTTCAAACTCTATTACAAAACTTGT
TGTTTTTATTTGTTGGCTAGCCATTCTAGCTGACGGCTATGATTTAGGTATTTACGGGGCCGTTCTGCCTAAGCTACTGG
AAGACAACAGCTGGGCACTATCACCAGCTCATGCTGGTACAATTGCAAGCTATGCTTTGTTTGGAATGTTTATTGGCGCT
ATTCTAGTAGGAACTATTACAGATTTAATTGGACGAAAATGGACACTTATATGCTGTTTAGCACTTTTTTCTATTACAAT
GGGCCTAGCTGCACTTGCTCCTTCTCCTGAATTATTTGGACTATGGCGATTTATCGGAGGAATTGGACTAGGCGGTGTCA
TTCCAACAGCTTCCGCACTTACTGTTGAATATTCACCAAAAAAGCGACAATCTTTTATTTATGCTCTTATGTTTACTGGC
TATCCTTTAGGTATCGTGTTAGGGGCTATTTTGTCCATGTTTATGTTAGAAGACTTCGGATGGAGAATTATGTTTGGCAT
CGGAATGATTCCACTACTCCTCATTCCTTTCATTATTCGTTATTTACCTGAATCCATTCAATTTTTATTATCACGTAATC
GCCAAGAAGAAGTGGATAAAATTCTTAATCGTTTTCAAATTGAATTCTATGCGAAAGATGAAACTCATCAAGCCCCATCT
AATATACGAAAGAAAAATGGATTTCTTACTTTATTCTCAAAAGAATACATAAAAGCAACGCTGCTTTTTTGGATCACTTA
TATAATGGGGATGTTTTTAATATACGGTTTAAATACTTGGTTACCTCAGATGATGCGACAGGCAGGATATCCTCTTGGAT
CTAGTTTATCATTTCTACTTATGCTAAATATTACTGCCGCTATCGGTGCATTATTTGCTGGAGCAATCGCAGATCGTATA
GGAGCCAAAATCGTTATTAGCATCTCCTATCTTATGGCAGCTATATGTATTGGACTATTAACAATTAAACCATCTGTTTC
AATCATTTATCTTTTAATTGGTCTTGCTGGAATTGGATCCGTCGGTATTACTCAAATATTAAATGCATATGTGACACAAT
ACTTCCCATCACATATCCGAGCTACTTCCTTAGGTTGGGGACTTGGACTTGGCCGGGTTGGTGCGATTGCTGGTCCTATT
CTTGTCGGTATTATTATGACAATGCAATATGACTTAGCATGGAATTTCTATTTATTCTCATTCGCAGGCCTTCTCGCGGC
TATATCTGTTTTCTTTATTCCTACAAAATAA

Upstream 100 bases:

>100_bases
CTTCTTTATTTGTTATAAAACCTTTTCAGATAAATTTCGACAGGAAGGAGGAAAATATTAACATGAAATAAAATAATATA
TTCATCTATAAATAAAAAGG

Downstream 100 bases:

>100_bases
AAAAGGGCACAAATTTACTCGTGCTCTTTTTTGTATACTTCGAATAACATATCTCGAAACAATGTATTTAAACTCTCAAT
ATCTATCCCTGATCCCTTTT

Product: benzoate transport protein

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPAHAGTIASYALFGMFIGA
ILVGTITDLIGRKWTLICCLALFSITMGLAALAPSPELFGLWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTG
YPLGIVLGAILSMFMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFYAKDETHQAPS
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRI
GAKIVISISYLMAAICIGLLTIKPSVSIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPI
LVGIIMTMQYDLAWNFYLFSFAGLLAAISVFFIPTK

Sequences:

>Translated_436_residues
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPAHAGTIASYALFGMFIGA
ILVGTITDLIGRKWTLICCLALFSITMGLAALAPSPELFGLWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTG
YPLGIVLGAILSMFMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFYAKDETHQAPS
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRI
GAKIVISISYLMAAICIGLLTIKPSVSIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPI
LVGIIMTMQYDLAWNFYLFSFAGLLAAISVFFIPTK
>Mature_436_residues
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPAHAGTIASYALFGMFIGA
ILVGTITDLIGRKWTLICCLALFSITMGLAALAPSPELFGLWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTG
YPLGIVLGAILSMFMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFYAKDETHQAPS
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRI
GAKIVISISYLMAAICIGLLTIKPSVSIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPI
LVGIIMTMQYDLAWNFYLFSFAGLLAAISVFFIPTK

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=434, Percent_Identity=26.7281105990783, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI166064021, Length=368, Percent_Identity=24.1847826086957, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7662270, Length=309, Percent_Identity=22.3300970873786, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI216548223, Length=309, Percent_Identity=23.6245954692557, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081723, Length=392, Percent_Identity=29.3367346938776, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87082404, Length=425, Percent_Identity=24.7058823529412, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87082159, Length=370, Percent_Identity=29.4594594594595, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786229, Length=372, Percent_Identity=27.1505376344086, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788074, Length=367, Percent_Identity=24.7956403269755, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788068, Length=404, Percent_Identity=26.4851485148515, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082231, Length=425, Percent_Identity=21.1764705882353, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789312, Length=349, Percent_Identity=26.9340974212034, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789207, Length=352, Percent_Identity=23.0113636363636, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790550, Length=384, Percent_Identity=25, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788292, Length=205, Percent_Identity=27.3170731707317, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790463, Length=277, Percent_Identity=25.6317689530686, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=428, Percent_Identity=24.5327102803738, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71989525, Length=362, Percent_Identity=25.414364640884, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71989531, Length=362, Percent_Identity=25.414364640884, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322632, Length=126, Percent_Identity=36.5079365079365, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320595, Length=210, Percent_Identity=27.1428571428571, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19922874, Length=435, Percent_Identity=23.9080459770115, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24640198, Length=446, Percent_Identity=23.3183856502242, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640196, Length=446, Percent_Identity=23.3183856502242, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640200, Length=446, Percent_Identity=23.3183856502242, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24668456, Length=359, Percent_Identity=26.1838440111421, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648211, Length=349, Percent_Identity=26.0744985673352, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47765; Mature: 47765

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEE
SPAHAGTIASYALFGMFIGAILVGTITDLIGRKWTLICCLALFSITMGLAALAPSPELFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTGYPLGIVLGAILSMFMLEDFG
HHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
WRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFYAKDETHQAPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCHH
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLL
HHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
MLNITAAIGALFAGAIADRIGAKIVISISYLMAAICIGLLTIKPSVSIIYLLIGLAGIGS
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCH
VGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPILVGIIMTMQYDLAWNFYLFS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGLLAAISVFFIPTK
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTMQPSAPPHLESTKTIFSNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEE
SPAHAGTIASYALFGMFIGAILVGTITDLIGRKWTLICCLALFSITMGLAALAPSPELFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTGYPLGIVLGAILSMFMLEDFG
HHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
WRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFYAKDETHQAPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCHH
NIRKKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLL
HHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
MLNITAAIGALFAGAIADRIGAKIVISISYLMAAICIGLLTIKPSVSIIYLLIGLAGIGS
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCH
VGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAIAGPILVGIIMTMQYDLAWNFYLFS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGLLAAISVFFIPTK
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]