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The map label for this gene is dppE [H]

Identifier: 49183228

GI number: 49183228

Start: 193281

End: 194921

Strand: Reverse

Name: dppE [H]

Synonym: BAS0195

Alternate gene names: 49183228

Gene position: 194921-193281 (Counterclockwise)

Preceding gene: 49183229

Following gene: 49183224

Centisome position: 3.73

GC content: 36.75

Gene sequence:

>1641_bases
ATGAAGAAAAAAGTTGTACCTGTTGTTGCATCTGTTTTAGGGGCAAGTCTATTACTAACTGCTTGCGGGGGAAATAAAGA
TAATGCAAGCGGAGCGAAAGCAAATGATAAAGCACCTGATAAACAGGCAATTAACTTATCATTTGCTTCAGAAATTCCAA
CAATGGATGTTGCAAAAGCAACGGATGGGGAATCCATGAACGTAATGCGCAATGTTTTTGAAGGGTTATATGCAATGGGA
GAAGATAATAAACCGATTCCTGGTGTTGCTGAGTCGGTTGACGTTAGTGCCGATAAAACGAAATATACATTCCACCTGCG
TGATTCAAAATGGTCAAACGGTACTCCTGTTACAGCAAAGGATTTCGTCTTTGCTTGGCAACGTGCCGTAAACCCTGATA
CAGCAGCTGAATATGCATTCTTATTCTTCGATATAAAGAATGCGAAACAAATAAACCAAAAACAATTACCGGTTGATCAA
TTAGGTATTAAAGCTGTTGATGATAAAACGTTAGAAGTACAACTAGATCGTCCTGTTCCCTACTTCTTAAGCTTAACGAC
ATTCTCAACATTCTTGCCAATTAATGAAGAGTACTTAAAGTCTCAAGGCGATAAATACGGTTTAGAAACAAATCATTTAA
TTTACAACGGTGCTTTCACATTAGATAACTGGAAACATGAGCAAAGCTTCCAATTGAAGAAGAATCCTAACTATTGGGAT
GCTAAAACTGTAAAATTAGAAGAAATCAACTTCAATGTCGTTAAAGATAAGTCTACAGAAGTGAACTTATATGATTCAGG
ACAAATTGATCGCGTTGCTTTAACTGCGGAGTTTGTTGATAAATATAAAGGCGATCCAAACTTCAAAGAACGCGCTGAAG
TTGGCATTCAATTTTTACGACTCAATCAAAAAAATGAAACATTAAAAAATCAGCATGCGCGCCTTGCTATTAACGGCGCA
ATGAATAAAAAAGCCTACGTAGAAACAATTTTAAATAACGGCGCTGTTCCAGCTGAAGGAATGATTCCTGCGAAATTTGC
AAAAAGTCCTGATGGCAACGACTTCCGTAAAGAAAATGGCAATCTAGTCAAAGATGATGTGAAAACAGCGAAAGAAAACT
GGAAAAAAGCGAAGCAAGAACTTGGTACTGACAAAGTAACAATTGAACTCTTAACAAGTGATAATGCTTTAGCTAAAAAA
ACTGGTGAATATTTAAAAGGTGAACTAGAAAAGAACTTAGATGGATTAACAGTGAATTTAAAACCACAACCACGTAAACA
ACAGTTAAAACTACTATTAAGTGGTGACTACGAAATCGGTATTGATGGCTGGGGCCCTGACTTCGCTGATCCAATTACAT
TCTTAGATTTATTTACAACAGATAGTGCTTACAACTTCGATAAATACTCTAACAAAGAGTACGATGAGCTAATTCATAAA
GTAAAAACAGATTTAGCTGGTGATGAAAAGGCACGGTTTGAAGCAATGAAGCAAGCTGAAAAAATTCTATTACAAGACGG
TGCTGTCGCTCCTTTATACCAACAAGGTCGTTCTTACTTACAACGCTCTTTCATTAAAGGACTTGTAACAACTGACTTCG
GTGGTGAGTTTAACTACAAGTGGACAGAAGTTGCAAAATAA

Upstream 100 bases:

>100_bases
CATGTACACATTTATAATAGGTTTTCTCTTCTTCTATAAATACACTTTAAGACATGGACATTATGACGTTACGAACAACA
CATTTTGGGAGGAACGAACA

Downstream 100 bases:

>100_bases
TAAGTGCTAATAAAAAGGTATCCCACCGAGGATACCTTTTTATTTTATGCTTCTTTAACTACAGAGCTTCTCCCCTTTAC
TATTCCTTTTATAGCTAAAG

Product: oligopeptide ABC transporter oligopeptide-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKATDGESMNVMRNVFEGLYAMG
EDNKPIPGVAESVDVSADKTKYTFHLRDSKWSNGTPVTAKDFVFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPVDQ
LGIKAVDDKTLEVQLDRPVPYFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKGDPNFKERAEVGIQFLRLNQKNETLKNQHARLAINGA
MNKKAYVETILNNGAVPAEGMIPAKFAKSPDGNDFRKENGNLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKK
TGEYLKGELEKNLDGLTVNLKPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYKWTEVAK

Sequences:

>Translated_546_residues
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKATDGESMNVMRNVFEGLYAMG
EDNKPIPGVAESVDVSADKTKYTFHLRDSKWSNGTPVTAKDFVFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPVDQ
LGIKAVDDKTLEVQLDRPVPYFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKGDPNFKERAEVGIQFLRLNQKNETLKNQHARLAINGA
MNKKAYVETILNNGAVPAEGMIPAKFAKSPDGNDFRKENGNLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKK
TGEYLKGELEKNLDGLTVNLKPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYKWTEVAK
>Mature_546_residues
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKATDGESMNVMRNVFEGLYAMG
EDNKPIPGVAESVDVSADKTKYTFHLRDSKWSNGTPVTAKDFVFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPVDQ
LGIKAVDDKTLEVQLDRPVPYFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKGDPNFKERAEVGIQFLRLNQKNETLKNQHARLAINGA
MNKKAYVETILNNGAVPAEGMIPAKFAKSPDGNDFRKENGNLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKK
TGEYLKGELEKNLDGLTVNLKPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYKWTEVAK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=544, Percent_Identity=30.8823529411765, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI87081878, Length=516, Percent_Identity=30.4263565891473, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1789397, Length=516, Percent_Identity=27.5193798449612, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1787762, Length=453, Percent_Identity=25.8278145695364, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789966, Length=470, Percent_Identity=24.0425531914894, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787052, Length=488, Percent_Identity=23.155737704918, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787551, Length=500, Percent_Identity=22.2, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1789887, Length=500, Percent_Identity=24.2, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61138; Mature: 61138

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKA
CCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECC
TDGESMNVMRNVFEGLYAMGEDNKPIPGVAESVDVSADKTKYTFHLRDSKWSNGTPVTAK
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHH
DFVFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPVDQLGIKAVDDKTLEVQLDRPVP
HHHHHHHHCCCCCCHHCEEEEEEEECCHHHHHHHCCCHHHHCCEEECCCEEEEEECCCCC
YFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
CEEEHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEECEEEECCCCCCCCEEECCCCCCCC
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKGDPNFKERAEVGIQFLR
CEEEEEEECCEEEEECCCCEEEEECCCCCCEEEEEHHHHHHHCCCCCHHHHHHHCEEEEE
LNQKNETLKNQHARLAINGAMNKKAYVETILNNGAVPAEGMIPAKFAKSPDGNDFRKENG
ECCCCHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCHHHCCC
NLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKKTGEYLKGELEKNLDGLTVNL
CEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEE
KPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
CCCCHHHHEEEEEECCEEEECCCCCCCCCCHHHHHHEEECCCCCCCCCCCCCHHHHHHHH
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYK
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCE
WTEVAK
ECCCCC
>Mature Secondary Structure
MKKKVVPVVASVLGASLLLTACGGNKDNASGAKANDKAPDKQAINLSFASEIPTMDVAKA
CCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECC
TDGESMNVMRNVFEGLYAMGEDNKPIPGVAESVDVSADKTKYTFHLRDSKWSNGTPVTAK
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHH
DFVFAWQRAVNPDTAAEYAFLFFDIKNAKQINQKQLPVDQLGIKAVDDKTLEVQLDRPVP
HHHHHHHHCCCCCCHHCEEEEEEEECCHHHHHHHCCCHHHHCCEEECCCEEEEEECCCCC
YFLSLTTFSTFLPINEEYLKSQGDKYGLETNHLIYNGAFTLDNWKHEQSFQLKKNPNYWD
CEEEHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEEECEEEECCCCCCCCEEECCCCCCCC
AKTVKLEEINFNVVKDKSTEVNLYDSGQIDRVALTAEFVDKYKGDPNFKERAEVGIQFLR
CEEEEEEECCEEEEECCCCEEEEECCCCCCEEEEEHHHHHHHCCCCCHHHHHHHCEEEEE
LNQKNETLKNQHARLAINGAMNKKAYVETILNNGAVPAEGMIPAKFAKSPDGNDFRKENG
ECCCCHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCHHHCCC
NLVKDDVKTAKENWKKAKQELGTDKVTIELLTSDNALAKKTGEYLKGELEKNLDGLTVNL
CEEHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEE
KPQPRKQQLKLLLSGDYEIGIDGWGPDFADPITFLDLFTTDSAYNFDKYSNKEYDELIHK
CCCCHHHHEEEEEECCEEEECCCCCCCCCCHHHHHHEEECCCCCCCCCCCCCHHHHHHHH
VKTDLAGDEKARFEAMKQAEKILLQDGAVAPLYQQGRSYLQRSFIKGLVTTDFGGEFNYK
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCE
WTEVAK
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]