BacMap

Definition	Bacillus anthracis str. Sterne chromosome, complete genome.
Accession	NC_005945
Length	5,228,663

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 49183207

GI number: 49183207

Start: 173894

End: 174529

Strand: Direct

Name: fabG [H]

Synonym: BAS0174

Alternate gene names: 49183207

Gene position: 173894-174529 (Clockwise)

Preceding gene: 49183201

Following gene: 49183212

Centisome position: 3.33

GC content: 38.21

Gene sequence:

>636_bases
ATGCCTTGGGGCGTTGATCAAAGTGAACAAATACAATTACAAGAAGAGTTACTAAAAAACGGTGTGAAAGTATCGAGTAT
GGAGTTAGATTTAACTCAGAATGATGCACCGAAAGAGCTTATAAATAAAGTTACTGAACAACTAGGCTACCCTCATATAT
TAATTAATAATGCAGCGTATTCTACGAATAATGATTTCTCTAATTTGACTGCTGAAGAATTAGATAAGCACTACATGGTC
AATATTCGTGCGACTACATTATTAAGTAGTCAATTTGCCCGAGGATTTGATAAGAAATCTGGTGGTAGAATTGTGAATAT
GACTTCGGGGCAATTTCAAGGGCCTATGGTTGGAGAACTGGCGTATGCAACAACGAAGGGGGCTATTGATGCTCTTACTA
GTTCGTTGTCAGCCGAGGTAGCTCATTTAGGAATAACAGTGAATGCAATTAACCCAGGTCCAACTGATACAGGCTGGATG
ACTGAAGAGATAAAGCAAGGATTAAAACCAATGTTTCCTTTTGGCAGAATTGGTGAGCCAAAGGATGCAGCAAGACTCAT
TAAGTTTTTAGTAAGTGAAGAAGCAGAGTGGATTACGGGACAAGTTATTCATTCAGAAGGTGGATTTAAAAGATAA

Upstream 100 bases:

>100_bases
TGTAAGTCGTTTAGATGGTATAGGCGCAGCAATTTGTAAAGAATTAGCTGAGGCTGGATAGAATATATTTTTTACGTATT
GGACAGAGTATGATAAAGAG

Downstream 100 bases:

>100_bases
GAAGAAGGTATCTCACCAGGGTGAGATACCTTCTTTTTTAATCTTTCTTCAATCTTCGTGCAATACCATTCCCTAAAGAC
TGTAATCCTTGAACGAGGAT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MPWGVDQSEQIQLQEELLKNGVKVSSMELDLTQNDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEELDKHYMV
NIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQGPMVGELAYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWM
TEEIKQGLKPMFPFGRIGEPKDAARLIKFLVSEEAEWITGQVIHSEGGFKR

Sequences:

>Translated_211_residues
MPWGVDQSEQIQLQEELLKNGVKVSSMELDLTQNDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEELDKHYMV
NIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQGPMVGELAYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWM
TEEIKQGLKPMFPFGRIGEPKDAARLIKFLVSEEAEWITGQVIHSEGGFKR
>Mature_210_residues
PWGVDQSEQIQLQEELLKNGVKVSSMELDLTQNDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEELDKHYMVN
IRATTLLSSQFARGFDKKSGGRIVNMTSGQFQGPMVGELAYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWMT
EEIKQGLKPMFPFGRIGEPKDAARLIKFLVSEEAEWITGQVIHSEGGFKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=194, Percent_Identity=29.3814432989691, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI7705925, Length=201, Percent_Identity=29.3532338308458, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI15277342, Length=191, Percent_Identity=27.2251308900524, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI126723750, Length=145, Percent_Identity=31.0344827586207, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4503301, Length=208, Percent_Identity=25.9615384615385, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=26.8817204301075, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI59889578, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788459, Length=211, Percent_Identity=30.8056872037915, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=32.7956989247312, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI87082100, Length=212, Percent_Identity=32.0754716981132, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI87082160, Length=209, Percent_Identity=28.7081339712919, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI2367175, Length=164, Percent_Identity=35.3658536585366, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI2367365, Length=181, Percent_Identity=28.1767955801105, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789208, Length=214, Percent_Identity=27.1028037383178, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786812, Length=219, Percent_Identity=26.027397260274, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1790717, Length=201, Percent_Identity=24.8756218905473, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789378, Length=213, Percent_Identity=27.2300469483568, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1787905, Length=198, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=167, Percent_Identity=31.7365269461078, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=217, Percent_Identity=29.9539170506912, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=218, Percent_Identity=29.3577981651376, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=218, Percent_Identity=29.8165137614679, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=219, Percent_Identity=29.6803652968037, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=209, Percent_Identity=28.2296650717703, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=218, Percent_Identity=27.9816513761468, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=217, Percent_Identity=28.110599078341, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=224, Percent_Identity=29.0178571428571, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=227, Percent_Identity=27.7533039647577, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=210, Percent_Identity=27.6190476190476, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=226, Percent_Identity=27.8761061946903, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=198, Percent_Identity=28.2828282828283, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=200, Percent_Identity=28.5, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=199, Percent_Identity=28.1407035175879, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=189, Percent_Identity=27.5132275132275, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=194, Percent_Identity=27.319587628866, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=201, Percent_Identity=26.3681592039801, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=218, Percent_Identity=27.0642201834862, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=217, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=208, Percent_Identity=23.5576923076923, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=177, Percent_Identity=28.2485875706215, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=165, Percent_Identity=31.5151515151515, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24643142, Length=204, Percent_Identity=30.8823529411765, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=28.7234042553192, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=29.3193717277487, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=200, Percent_Identity=31.5, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355319, Length=204, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21357041, Length=192, Percent_Identity=28.6458333333333, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24644337, Length=217, Percent_Identity=29.4930875576037, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 23142; Mature: 23011

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWGVDQSEQIQLQEELLKNGVKVSSMELDLTQNDAPKELINKVTEQLGYPHILINNAAY
CCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCC
STNNDFSNLTAEELDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQGPMVGEL
CCCCCCCCCCHHHCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHH
AYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWMTEEIKQGLKPMFPFGRIGEP
HHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
KDAARLIKFLVSEEAEWITGQVIHSEGGFKR
HHHHHHHHHHHHCCCCHHEEEEEECCCCCCC
>Mature Secondary Structure 
PWGVDQSEQIQLQEELLKNGVKVSSMELDLTQNDAPKELINKVTEQLGYPHILINNAAY
CCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCC
STNNDFSNLTAEELDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQGPMVGEL
CCCCCCCCCCHHHCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHH
AYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWMTEEIKQGLKPMFPFGRIGEP
HHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
KDAARLIKFLVSEEAEWITGQVIHSEGGFKR
HHHHHHHHHHHHCCCCHHEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]