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The map label for this gene is gntK [H]

Identifier: 49183197

GI number: 49183197

Start: 162515

End: 163516

Strand: Direct

Name: gntK [H]

Synonym: BAS0164

Alternate gene names: 49183197

Gene position: 162515-163516 (Clockwise)

Preceding gene: 49183196

Following gene: 49183198

Centisome position: 3.11

GC content: 39.32

Gene sequence:

>1002_bases
ATGGGTATGATGAACTTAAAAACGCTAGATTGGGATGAGGAAGCTTTAAAAATTGCTGGTATAACATCAGCTCAATTATC
TAAACTCGTACCAACCACCAAAATATTCAGCAACTGCAATCCAGATTTAGCCCAAAAGATTGGTATCGATTCCCAAACAC
CGTTTGTCATTGGTGCCAGTGATGGGGTGCTTTCTAATCTAGGTGTGAATGCAATTCGGAAAGGGGAGATTGCTGTCACA
ATTGGAACAAGTGGTGCTATTCGGACCATTATTGATAAACCACAAACAGATAAAAAAGGAAGAATATTTTGTTATGCCTT
AACCGAAAAGCATTGGGTAATTGGTGGACCGGTAAACAATGGAGGGATGGTCCTTCGCTGGATTCGTGATGAACTTGCTT
CATCAGAAGTAGAAACTGCGAAAAGACTAGGAATTGATCCATACGATGTATTAACTAAAATAGCAGAACGCGTGAGACCT
GGTGCAGACGGATTATTATTCCATCCATACCTCACAGGGGAACGTGCACCATTATGGAATCCAGATGTACGTGGCTCCTT
CTTTGGTTTAACGATGTCACATAAGAAGGAACATATGATTCGTGCAGCTTTAGAGGGTGTTATATATAATTTATACACTG
TATTTTTAGCATTAACAGAATGTATGGATGGTCCTGTAACTCGTATTCAAGCAACAGGCGGCTTCGCAAGGTCTGACGTT
TGGCGACAGATGATGTCCGATATTTTCGCATCTGAAGTCGTTGTTCCAAAGAGCTACGAAAGCTCTTGTCTAGGTGCATG
TATATTAGGTCTCTATGCCACAGGAAAAATTGATTCTTTTGAAATCGTTTCCGAAATGGTTGGTAGTACCTACAAACATA
CACCGAAAGAAGAAGCAACAAAAGAATACAGACAATTACTGCCTATATTTATTAACCTATCAAGGGCGTTAGAAGATGAT
TATACACGCATTGCAAATTATCAAAGAAATTTAATAAAGTAA

Upstream 100 bases:

>100_bases
GGAAATTGCTATTAGAACGAAAAAATATATTGGAATCAAAGAATATATCTTCAAAAAATTCTTTGATCAATATGTTGTTG
ATCATTCCATCGCCTAGTGC

Downstream 100 bases:

>100_bases
AACTTTCATCAGTAACCTCCCACGCCTCGCTTCTATCTAAATCTCGAGGTGATGGGGGCCTTACTGCCCACGAATAGCGG
GATAAATACAAATACAGCTA

Product: gluconate kinase, C-terminus

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MGMMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGASDGVLSNLGVNAIRKGEIAVT
IGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRP
GADGLLFHPYLTGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDV
WRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKEYRQLLPIFINLSRALEDD
YTRIANYQRNLIK

Sequences:

>Translated_333_residues
MGMMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGASDGVLSNLGVNAIRKGEIAVT
IGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRP
GADGLLFHPYLTGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDV
WRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKEYRQLLPIFINLSRALEDD
YTRIANYQRNLIK
>Mature_332_residues
GMMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGASDGVLSNLGVNAIRKGEIAVTI
GTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPG
ADGLLFHPYLTGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDVW
RQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKEYRQLLPIFINLSRALEDDY
TRIANYQRNLIK

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=276, Percent_Identity=24.2753623188406, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI189409120, Length=273, Percent_Identity=24.9084249084249, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4504007, Length=273, Percent_Identity=24.9084249084249, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI41393575, Length=266, Percent_Identity=24.0601503759398, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI88196792, Length=263, Percent_Identity=26.2357414448669, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789987, Length=323, Percent_Identity=26.625386996904, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787789, Length=325, Percent_Identity=26.4615384615385, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790361, Length=307, Percent_Identity=26.7100977198697, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790005, Length=329, Percent_Identity=26.1398176291793, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789168, Length=315, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789138, Length=324, Percent_Identity=23.7654320987654, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321755, Length=319, Percent_Identity=25.705329153605, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654573, Length=277, Percent_Identity=25.9927797833935, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17864214, Length=277, Percent_Identity=25.9927797833935, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24655555, Length=284, Percent_Identity=24.2957746478873, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24655560, Length=284, Percent_Identity=24.2957746478873, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24655570, Length=284, Percent_Identity=24.2957746478873, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24655574, Length=284, Percent_Identity=24.2957746478873, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24655565, Length=284, Percent_Identity=24.2957746478873, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24656372, Length=290, Percent_Identity=24.4827586206897, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21357867, Length=290, Percent_Identity=24.4827586206897, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24656367, Length=290, Percent_Identity=24.4827586206897, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 36833; Mature: 36702

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGAS
CCCCCCCCCCCCHHHHEEECCCHHHHHHHCCHHHHHHCCCHHHHHHCCCCCCCCEEEECC
DGVLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNN
CCHHHHCCCCCEECCCEEEEECCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCC
GGMVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLTGERAPLWN
CCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCEECCCCCCCCC
PDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDV
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
WRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEAT
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHH
KEYRQLLPIFINLSRALEDDYTRIANYQRNLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GMMNLKTLDWDEEALKIAGITSAQLSKLVPTTKIFSNCNPDLAQKIGIDSQTPFVIGAS
CCCCCCCCCCCHHHHEEECCCHHHHHHHCCHHHHHHCCCHHHHHHCCCCCCCCEEEECC
DGVLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNN
CCHHHHCCCCCEECCCEEEEECCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCC
GGMVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLTGERAPLWN
CCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCEECCCCCCCCC
PDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDV
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
WRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEAT
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHH
KEYRQLLPIFINLSRALEDDYTRIANYQRNLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]