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The map label for this gene is dck [H]

Identifier: 49183053

GI number: 49183053

Start: 22457

End: 23125

Strand: Reverse

Name: dck [H]

Synonym: BAS0017

Alternate gene names: 49183053

Gene position: 23125-22457 (Counterclockwise)

Preceding gene: 49183054

Following gene: 49183046

Centisome position: 0.44

GC content: 35.87

Gene sequence:

>669_bases
ATGAATTTAAGGCAAAAATATGATATACCAAATGACGCAGTAATCACTATCGCTGGAACAGTAGGTGTCGGTAAATCCAC
TATGACAACTGCATTAGCTAACGCTTTAGGATATCGCACATCATTTGAAAAGGTAGATTCTAACCCGTATTTGGACAAGT
TCTATGCTGATTTCACACGCTGGAGCTTTCACTTACAAGTGTACTTTTTAGCAGAACGATTTAAAGAACAAAAAAGGATT
TTTGAATACGGTGGTGGTTTTGTTCAAGATCGCTCTATCTATGAAGACACTGGCATTTTTGCAAAAATGCATCACGAAAA
GGGTACAATGACGGAAACTGATTATGAAACATATAAAGGTTTATTTGACGCTATGGTCATGACTCCTTACTTCCCTCATC
CAGATTTACTAATCTACTTAGAAGGTTCTTTCGATGATATCGTTGATCGTATCCAAGAACGTGGACGTCCGATGGAACAG
CAAACGCCAATTGAGTATTGGAAAGAGATGCATGGGCGTTATGAAAACTGGATTAATAACTTTAATTCATGCCCTGTCTT
ACGATTAAATATTAATGAATACGATATTTTAAAAGATGGCGATTCCATTGAACCAATCATTAAAAAGATCGGCCATTTTT
TAAAACAAACACGTAAACTTGTAAAATAA

Upstream 100 bases:

>100_bases
AATTTAACGGAGACGATATGGATTTTGTAAAAAATCCTGATGATTTAAACGTCATCCTATCTGCCCTTCAAAATACTCTC
TTAAAGGAGTCGAAATAATA

Downstream 100 bases:

>100_bases
AAAACCCGTGCATACGCACGGGTTTTTCTACTAAATTACTTCTTCTTTGTCGGAGCAATAATTTCACTCTCAGATTTTCC
AGCGTTAATACGCTGACGAA

Product: deoxynucleoside kinase family protein

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNLRQKYDIPNDAVITIAGTVGVGKSTMTTALANALGYRTSFEKVDSNPYLDKFYADFTRWSFHLQVYFLAERFKEQKRI
FEYGGGFVQDRSIYEDTGIFAKMHHEKGTMTETDYETYKGLFDAMVMTPYFPHPDLLIYLEGSFDDIVDRIQERGRPMEQ
QTPIEYWKEMHGRYENWINNFNSCPVLRLNINEYDILKDGDSIEPIIKKIGHFLKQTRKLVK

Sequences:

>Translated_222_residues
MNLRQKYDIPNDAVITIAGTVGVGKSTMTTALANALGYRTSFEKVDSNPYLDKFYADFTRWSFHLQVYFLAERFKEQKRI
FEYGGGFVQDRSIYEDTGIFAKMHHEKGTMTETDYETYKGLFDAMVMTPYFPHPDLLIYLEGSFDDIVDRIQERGRPMEQ
QTPIEYWKEMHGRYENWINNFNSCPVLRLNINEYDILKDGDSIEPIIKKIGHFLKQTRKLVK
>Mature_222_residues
MNLRQKYDIPNDAVITIAGTVGVGKSTMTTALANALGYRTSFEKVDSNPYLDKFYADFTRWSFHLQVYFLAERFKEQKRI
FEYGGGFVQDRSIYEDTGIFAKMHHEKGTMTETDYETYKGLFDAMVMTPYFPHPDLLIYLEGSFDDIVDRIQERGRPMEQ
QTPIEYWKEMHGRYENWINNFNSCPVLRLNINEYDILKDGDSIEPIIKKIGHFLKQTRKLVK

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

Organism=Homo sapiens, GI4503269, Length=243, Percent_Identity=27.5720164609054, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI18426967, Length=237, Percent_Identity=24.0506329113924, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 26091; Mature: 26091

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRQKYDIPNDAVITIAGTVGVGKSTMTTALANALGYRTSFEKVDSNPYLDKFYADFTR
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHH
WSFHLQVYFLAERFKEQKRIFEYGGGFVQDRSIYEDTGIFAKMHHEKGTMTETDYETYKG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHEEEECCCCCCCCCHHHHHHH
LFDAMVMTPYFPHPDLLIYLEGSFDDIVDRIQERGRPMEQQTPIEYWKEMHGRYENWINN
HHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
FNSCPVLRLNINEYDILKDGDSIEPIIKKIGHFLKQTRKLVK
CCCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLRQKYDIPNDAVITIAGTVGVGKSTMTTALANALGYRTSFEKVDSNPYLDKFYADFTR
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHH
WSFHLQVYFLAERFKEQKRIFEYGGGFVQDRSIYEDTGIFAKMHHEKGTMTETDYETYKG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHEEEECCCCCCCCCHHHHHHH
LFDAMVMTPYFPHPDLLIYLEGSFDDIVDRIQERGRPMEQQTPIEYWKEMHGRYENWINN
HHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
FNSCPVLRLNINEYDILKDGDSIEPIIKKIGHFLKQTRKLVK
CCCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]