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The map label for this gene is nrdR

Identifier: 46447433

GI number: 46447433

Start: 2151804

End: 2152292

Strand: Reverse

Name: nrdR

Synonym: pc1799

Alternate gene names: 46447433

Gene position: 2152292-2151804 (Counterclockwise)

Preceding gene: 46447435

Following gene: 46447432

Centisome position: 89.14

GC content: 34.97

Gene sequence:

>489_bases
ATGAGATGTCCCTTTTGTCAATTTGAGGGATTGAAAGTGACTGACTCTCGAGATGCAATGGAAATGAATGCGATTAGAAG
AAGAAGAGAGTGCTTGAATTGTCTTAAGCGTTTTACTACTTTTGAAACAATCGAATTGACAGTACAAGTGCAAAAAAGAG
ATGGAACTTATGAGGATTTTCAACAACATAAGTTAATTAATGGATTAGCTGCTGCATGTAGGCATACCAAAATTAGCCAT
GATCAGGTAATCAGTTTAGCTGCTCAAATGACAAACGAATTAATGCAGTCTCAAATACAACAAATAAGCACCACACAGTT
AGGTGAGATGGCCATGAAACATTTACAAAGTCTTGACCCCATCGCTTATATTCGTTTTGCGTGTGTGTATAAAAGATTTA
AAGATTTAGGTGAGTTAGAAGAAGCAATTAAAACAATTCAATCTAAAGACGAAGACAAATCTTGCTCGATATTAAAGGAT
TTGTTATAG

Upstream 100 bases:

>100_bases
TTTTTAAATAGGAGCGATTGAATTTATACAATGAAGAAAAGTCGAATTTGATGTATGAACAACTTTGACTGAAAATGAAT
GAACTCATGGAGGATTGAGC

Downstream 100 bases:

>100_bases
GCTTCGAACTTTATTGTTAAAAGCGCAAATAGACGATAGGAGGTCAAAAATGGCATTAAAAAAAACAGAAGTTGCAAAGT
TTAAAAAACGTTTAGAAGAT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MRCPFCQFEGLKVTDSRDAMEMNAIRRRRECLNCLKRFTTFETIELTVQVQKRDGTYEDFQQHKLINGLAAACRHTKISH
DQVISLAAQMTNELMQSQIQQISTTQLGEMAMKHLQSLDPIAYIRFACVYKRFKDLGELEEAIKTIQSKDEDKSCSILKD
LL

Sequences:

>Translated_162_residues
MRCPFCQFEGLKVTDSRDAMEMNAIRRRRECLNCLKRFTTFETIELTVQVQKRDGTYEDFQQHKLINGLAAACRHTKISH
DQVISLAAQMTNELMQSQIQQISTTQLGEMAMKHLQSLDPIAYIRFACVYKRFKDLGELEEAIKTIQSKDEDKSCSILKD
LL
>Mature_162_residues
MRCPFCQFEGLKVTDSRDAMEMNAIRRRRECLNCLKRFTTFETIELTVQVQKRDGTYEDFQQHKLINGLAAACRHTKISH
DQVISLAAQMTNELMQSQIQQISTTQLGEMAMKHLQSLDPIAYIRFACVYKRFKDLGELEEAIKTIQSKDEDKSCSILKD
LL

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=37.8378378378378, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_PARUW (Q6MA76)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008798.1
- STRING:   Q6MA76
- GeneID:   2781060
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1799
- NMPDR:   fig|264201.1.peg.1799
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   CPRO264201:PC1799-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18755; Mature: 18755

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCQFEGLKVTDSRDAMEMNAIRRRRECLNCLKRFTTFETIELTVQVQKRDGTYEDF
CCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHH
QQHKLINGLAAACRHTKISHDQVISLAAQMTNELMQSQIQQISTTQLGEMAMKHLQSLDP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
IAYIRFACVYKRFKDLGELEEAIKTIQSKDEDKSCSILKDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHC
>Mature Secondary Structure
MRCPFCQFEGLKVTDSRDAMEMNAIRRRRECLNCLKRFTTFETIELTVQVQKRDGTYEDF
CCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHH
QQHKLINGLAAACRHTKISHDQVISLAAQMTNELMQSQIQQISTTQLGEMAMKHLQSLDP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
IAYIRFACVYKRFKDLGELEEAIKTIQSKDEDKSCSILKDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA