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The map label for this gene is hflX [H]

Identifier: 46447400

GI number: 46447400

Start: 2118506

End: 2119840

Strand: Reverse

Name: hflX [H]

Synonym: pc1766

Alternate gene names: 46447400

Gene position: 2119840-2118506 (Counterclockwise)

Preceding gene: 46447401

Following gene: 46447399

Centisome position: 87.8

GC content: 36.63

Gene sequence:

>1335_bases
ATGAAAAATGATAAAACTGTCAAAGATGAATCAGATTTTATTTTACATGAAGAAGAAAAAAACCAGAAAGCTTTATTGAT
TTCGGTTTATCAAGGGAATAAGCAACTAAGGCTTTGTGAAGAACACTTAGAAGAGTTGGCTTTATTAGCTTATACATTTG
GGATTGAAGTTGCAAAAAAAGAGCCTTGCTCACTACGAAAATTCGATGCTTCTACCTATGTTAGTAAGGGTAAGCTAGAG
GAATTAATTCAAATCGCTAATGAATTAGCTGTAGATCTTATTATTTTTGATGATGAAATCACGCCTGCTCAGCAGAGAAA
TTTACAAGCAGCTTTCAATAAGCCGGTTATTGATCGAACAGAATTGATTTTGGGTGTTTTCGCGCAGAGAGCTCACACTA
AAGAAGCGCGTTTACAAATTGAATTAGCAAAAATTAAATATGAAGCTCCTCGCCTAAAAAGATTGTGGACTCACCTTTCT
CGTCAGCAGGGAACTTCAGGTTCTGGCGGGGGAGGGGCTTATTTAAAAGGAGAAGGGGAAAAACAAATTGAAATTGATAA
ACGAATTCTCAAACGTAAAATGGACGTTTTACAAAAAGAGATAGACGATGTTAAAGCTGTTCGTGAGACGCAACGTTTAT
CAAGAGTCCGCTCTGCAATTCCTGTTTTTGCTATTATTGGTTATACGAATGCAGGAAAGTCTACTCTTCTCAATGCTTTG
ACTGATGCAGGCGTATTTGTGGAAGATAAGCTTTTTGCAACGCTCGATACGACCACCCGAAAATTTACTCTGCCTAATAA
CCAAGATATTTTAATTGTCGACACCGTTGGATTCATTCGCAAGCTCCCTCACTTACTAGTAGCTGCCTTTAAAAGCACGC
TTGAAGAAGCAATTGAAGCAGATATTCTTTTACATTTGATTGATGTCAGTCATCCCATGGCAGAAGAACAGGCCGCTACA
ACTTATGAAGTTTTACAAGAACTTGGAGCAGGAAAAAAGCCTATTATTACAGTTTTAAATAAAATCGATCAATGCGAACA
TCCTCATATGATTCATCGAATTAGGATGAGTTATCCAAAAAATGTGCAGATTTCAGCTTTAAAAAAAATAGGATTTGAAG
AGCTTCAAGAAGCCATGATTCAGGAATTGAGCCGCCAAAGACAAGTTGCCGAATTTCGTATTCCTCAAAGTGATTACGGT
AGTGTGAGTGAGATTATCCGTTTAGGGCATATTTTATCTCAAGATTATGAAGATAATGATGTTTTACTAAAAGTTGATTT
GCCAGCATTGATTGTTGATAAATATGCGCATTATCAAATCTTAGCAGAAAGATAG

Upstream 100 bases:

>100_bases
TGAATTAGATCATGATAAAGTAAATGCTTATCTCCCCAAACATGTGAGACTGGCTTATGATGGCTTAGAGATAGAATTTA
ATGATTATAAGGAATAAGAA

Downstream 100 bases:

>100_bases
GATAGGGATGAGAATAAATGAGCATTCCATTCAGTCTTTACCTAAAGAAGAAAGACCTAGAGAGCGATTAATTCGGCATG
GCGCAGATTCTTTATCGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKNDKTVKDESDFILHEEEKNQKALLISVYQGNKQLRLCEEHLEELALLAYTFGIEVAKKEPCSLRKFDASTYVSKGKLE
ELIQIANELAVDLIIFDDEITPAQQRNLQAAFNKPVIDRTELILGVFAQRAHTKEARLQIELAKIKYEAPRLKRLWTHLS
RQQGTSGSGGGGAYLKGEGEKQIEIDKRILKRKMDVLQKEIDDVKAVRETQRLSRVRSAIPVFAIIGYTNAGKSTLLNAL
TDAGVFVEDKLFATLDTTTRKFTLPNNQDILIVDTVGFIRKLPHLLVAAFKSTLEEAIEADILLHLIDVSHPMAEEQAAT
TYEVLQELGAGKKPIITVLNKIDQCEHPHMIHRIRMSYPKNVQISALKKIGFEELQEAMIQELSRQRQVAEFRIPQSDYG
SVSEIIRLGHILSQDYEDNDVLLKVDLPALIVDKYAHYQILAER

Sequences:

>Translated_444_residues
MKNDKTVKDESDFILHEEEKNQKALLISVYQGNKQLRLCEEHLEELALLAYTFGIEVAKKEPCSLRKFDASTYVSKGKLE
ELIQIANELAVDLIIFDDEITPAQQRNLQAAFNKPVIDRTELILGVFAQRAHTKEARLQIELAKIKYEAPRLKRLWTHLS
RQQGTSGSGGGGAYLKGEGEKQIEIDKRILKRKMDVLQKEIDDVKAVRETQRLSRVRSAIPVFAIIGYTNAGKSTLLNAL
TDAGVFVEDKLFATLDTTTRKFTLPNNQDILIVDTVGFIRKLPHLLVAAFKSTLEEAIEADILLHLIDVSHPMAEEQAAT
TYEVLQELGAGKKPIITVLNKIDQCEHPHMIHRIRMSYPKNVQISALKKIGFEELQEAMIQELSRQRQVAEFRIPQSDYG
SVSEIIRLGHILSQDYEDNDVLLKVDLPALIVDKYAHYQILAER
>Mature_444_residues
MKNDKTVKDESDFILHEEEKNQKALLISVYQGNKQLRLCEEHLEELALLAYTFGIEVAKKEPCSLRKFDASTYVSKGKLE
ELIQIANELAVDLIIFDDEITPAQQRNLQAAFNKPVIDRTELILGVFAQRAHTKEARLQIELAKIKYEAPRLKRLWTHLS
RQQGTSGSGGGGAYLKGEGEKQIEIDKRILKRKMDVLQKEIDDVKAVRETQRLSRVRSAIPVFAIIGYTNAGKSTLLNAL
TDAGVFVEDKLFATLDTTTRKFTLPNNQDILIVDTVGFIRKLPHLLVAAFKSTLEEAIEADILLHLIDVSHPMAEEQAAT
TYEVLQELGAGKKPIITVLNKIDQCEHPHMIHRIRMSYPKNVQISALKKIGFEELQEAMIQELSRQRQVAEFRIPQSDYG
SVSEIIRLGHILSQDYEDNDVLLKVDLPALIVDKYAHYQILAER

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=261, Percent_Identity=36.0153256704981, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI310133116, Length=243, Percent_Identity=36.2139917695473, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI310124269, Length=218, Percent_Identity=36.697247706422, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI310124267, Length=218, Percent_Identity=36.697247706422, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI310124171, Length=218, Percent_Identity=36.697247706422, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI310124169, Length=218, Percent_Identity=36.697247706422, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1790615, Length=419, Percent_Identity=37.708830548926, Blast_Score=256, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17561038, Length=277, Percent_Identity=33.2129963898917, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24650079, Length=376, Percent_Identity=30.3191489361702, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50345; Mature: 50345

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNDKTVKDESDFILHEEEKNQKALLISVYQGNKQLRLCEEHLEELALLAYTFGIEVAKK
CCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEECCC
EPCSLRKFDASTYVSKGKLEELIQIANELAVDLIIFDDEITPAQQRNLQAAFNKPVIDRT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHCHHHHHCCCCCHHH
ELILGVFAQRAHTKEARLQIELAKIKYEAPRLKRLWTHLSRQQGTSGSGGGGAYLKGEGE
HHHHHHHHHHHCCHHHHEEEEEEEHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCC
KQIEIDKRILKRKMDVLQKEIDDVKAVRETQRLSRVRSAIPVFAIIGYTNAGKSTLLNAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHH
TDAGVFVEDKLFATLDTTTRKFTLPNNQDILIVDTVGFIRKLPHLLVAAFKSTLEEAIEA
HHCCCEEECHHEEEECCCCEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
DILLHLIDVSHPMAEEQAATTYEVLQELGAGKKPIITVLNKIDQCEHPHMIHRIRMSYPK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCC
NVQISALKKIGFEELQEAMIQELSRQRQVAEFRIPQSDYGSVSEIIRLGHILSQDYEDND
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCC
VLLKVDLPALIVDKYAHYQILAER
EEEEECCCHHHHHHHHHHEEEECC
>Mature Secondary Structure
MKNDKTVKDESDFILHEEEKNQKALLISVYQGNKQLRLCEEHLEELALLAYTFGIEVAKK
CCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEECCC
EPCSLRKFDASTYVSKGKLEELIQIANELAVDLIIFDDEITPAQQRNLQAAFNKPVIDRT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHCHHHHHCCCCCHHH
ELILGVFAQRAHTKEARLQIELAKIKYEAPRLKRLWTHLSRQQGTSGSGGGGAYLKGEGE
HHHHHHHHHHHCCHHHHEEEEEEEHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCC
KQIEIDKRILKRKMDVLQKEIDDVKAVRETQRLSRVRSAIPVFAIIGYTNAGKSTLLNAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHH
TDAGVFVEDKLFATLDTTTRKFTLPNNQDILIVDTVGFIRKLPHLLVAAFKSTLEEAIEA
HHCCCEEECHHEEEECCCCEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
DILLHLIDVSHPMAEEQAATTYEVLQELGAGKKPIITVLNKIDQCEHPHMIHRIRMSYPK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCC
NVQISALKKIGFEELQEAMIQELSRQRQVAEFRIPQSDYGSVSEIIRLGHILSQDYEDND
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCC
VLLKVDLPALIVDKYAHYQILAER
EEEEECCCHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]