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The map label for this gene is atpD [H]

Identifier: 46447302

GI number: 46447302

Start: 2006004

End: 2007464

Strand: Reverse

Name: atpD [H]

Synonym: pc1668

Alternate gene names: 46447302

Gene position: 2007464-2006004 (Counterclockwise)

Preceding gene: 46447303

Following gene: 46447301

Centisome position: 83.14

GC content: 39.84

Gene sequence:

>1461_bases
GTGAATTTTTCGAATCATTTGAAGAAACTCAATAGAAAAGGCTCAAATAAAAATAAAAGGCAAATGATGGCGGTAGGAAA
AGTCAAACAGATTGTAGGTCCCACATTAGATATCGAGTTTCCTCCTGGGCAGCTTCCAAACATTTTAAATGCGATTAAAA
TCATTGATCCCAAAGATCAACGAGAATTAATTGCTGAAGTTGCGATGCACTTAGGAGATAACCAAGTTCGTTGTATTGCC
CTATCATCTACAGATGGTTTGGTGAGAGAAGCCCAAGCCGTTGATACTGAAGCTCCTATTTCTATTCCTGTGGGAAGTCC
AACACTTGGCCGGCTCCTTAATGTCCTAGGTCAACCGATCGACGAAATGGGAGCTATCGAAAACGCTGAAATTTCTCCTA
TTCACAAAGCTTCCCCCACTTTCGAAGAGCAAGATACGCAGGGAGTCATTTTTGAAACAGGGATTAAGGTTATTGACCTT
CTTTGCCCCTATACAAAAGGAGGGAAAGTTGGATTGTTTGGAGGGGCAGGAGTTGGTAAATCAGTCATTGTAATGGAATT
AATTCATAACATTGCCACCCATCATGGAGGCTATTCTGTTTTTTGCGGAATCGGGGAAAGAACAAGAGAAGGAAATGATT
TATGGTTAGAAATGAAAGAGTCCGGTATTCTCTCTAAGACTAGTCTCGTATTTGGCCAGATGAACGAACCTCCTGGGGCA
AGAATGCGAGTAGGTTTAACAGGATTAACGATGGCAGAGCATTTTAGAGACCAAGAGCATCAAAATGTCCTTTTATTCAT
TGATAATATTTTCCGTTTTGTTCAAGCAGGATCAGAAGTTTCTGCGTTGCTAGGTAGAATGCCGTCCGCTGTCGGTTATC
AGCCAACTTTAGCAAGTGAAATTGGAAGTTTACAAGAAAGAATCACTTCGACAAAGCATGGTTCTATTACCTCAGTCCAA
GCGATTTATGTTCCAGCAGATGATTATACAGATCCGGCACCAGCTAGTATTTTTCCCCATTTAGATGCTGCAACAACTCT
CTCGCGTCAAATTGCGGAACTGGGCATTTATCCAGCTGTAGATCCTTTAAATTCAAGTTCGCGGATTTTAGACCCCCACG
TTTTAGGTGAAGAGCATTATCAGGTTGCTAGACAAGTGCAAAAAGTTTTGCAGCGTTATAAAGATTTGCAAGACATCATT
GCAATTTTGGGAATTGATGAATTATCTGAAGAAGATCAGTTAACAGTTTCTCGTGCTCGTCGCATTCAAAAATTTTTATC
GCAACCATTTTTTGTTGCCGAAACGTTTACAGGAAAAAAAGGACGTTTTGTTAAATTGCCTGATACTATCAAAGGATTCA
AAATGATAGTAGAAGGCGAAATGGATAATATTCCTGAGCAAGCTTTTTATATGGTGGGAACAATTGAAGAAGTTTTCGAA
AAAGCTGAGCAAATGAAATAA

Upstream 100 bases:

>100_bases
GGCATCACTAAAGAGATGTTAGAAATCACTTCTGGAGCAGAAGGATTAAAGTAAAGAATAGTAAAAGAATAGTAAACGAG
ACAATATAGCGATTTCCTTT

Downstream 100 bases:

>100_bases
GGTTAGGGTGATTACAGATGCTTTATCCATTATCCATTTTAACTTCTGAAAAAAATGTCTTTAATGAAGACGTTTATTCT
GTGAATGTACCAGGCGCTGA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNFSNHLKKLNRKGSNKNKRQMMAVGKVKQIVGPTLDIEFPPGQLPNILNAIKIIDPKDQRELIAEVAMHLGDNQVRCIA
LSSTDGLVREAQAVDTEAPISIPVGSPTLGRLLNVLGQPIDEMGAIENAEISPIHKASPTFEEQDTQGVIFETGIKVIDL
LCPYTKGGKVGLFGGAGVGKSVIVMELIHNIATHHGGYSVFCGIGERTREGNDLWLEMKESGILSKTSLVFGQMNEPPGA
RMRVGLTGLTMAEHFRDQEHQNVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLASEIGSLQERITSTKHGSITSVQ
AIYVPADDYTDPAPASIFPHLDAATTLSRQIAELGIYPAVDPLNSSSRILDPHVLGEEHYQVARQVQKVLQRYKDLQDII
AILGIDELSEEDQLTVSRARRIQKFLSQPFFVAETFTGKKGRFVKLPDTIKGFKMIVEGEMDNIPEQAFYMVGTIEEVFE
KAEQMK

Sequences:

>Translated_486_residues
MNFSNHLKKLNRKGSNKNKRQMMAVGKVKQIVGPTLDIEFPPGQLPNILNAIKIIDPKDQRELIAEVAMHLGDNQVRCIA
LSSTDGLVREAQAVDTEAPISIPVGSPTLGRLLNVLGQPIDEMGAIENAEISPIHKASPTFEEQDTQGVIFETGIKVIDL
LCPYTKGGKVGLFGGAGVGKSVIVMELIHNIATHHGGYSVFCGIGERTREGNDLWLEMKESGILSKTSLVFGQMNEPPGA
RMRVGLTGLTMAEHFRDQEHQNVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLASEIGSLQERITSTKHGSITSVQ
AIYVPADDYTDPAPASIFPHLDAATTLSRQIAELGIYPAVDPLNSSSRILDPHVLGEEHYQVARQVQKVLQRYKDLQDII
AILGIDELSEEDQLTVSRARRIQKFLSQPFFVAETFTGKKGRFVKLPDTIKGFKMIVEGEMDNIPEQAFYMVGTIEEVFE
KAEQMK
>Mature_486_residues
MNFSNHLKKLNRKGSNKNKRQMMAVGKVKQIVGPTLDIEFPPGQLPNILNAIKIIDPKDQRELIAEVAMHLGDNQVRCIA
LSSTDGLVREAQAVDTEAPISIPVGSPTLGRLLNVLGQPIDEMGAIENAEISPIHKASPTFEEQDTQGVIFETGIKVIDL
LCPYTKGGKVGLFGGAGVGKSVIVMELIHNIATHHGGYSVFCGIGERTREGNDLWLEMKESGILSKTSLVFGQMNEPPGA
RMRVGLTGLTMAEHFRDQEHQNVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLASEIGSLQERITSTKHGSITSVQ
AIYVPADDYTDPAPASIFPHLDAATTLSRQIAELGIYPAVDPLNSSSRILDPHVLGEEHYQVARQVQKVLQRYKDLQDII
AILGIDELSEEDQLTVSRARRIQKFLSQPFFVAETFTGKKGRFVKLPDTIKGFKMIVEGEMDNIPEQAFYMVGTIEEVFE
KAEQMK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=468, Percent_Identity=65.5982905982906, Blast_Score=633, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=323, Percent_Identity=27.5541795665635, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19913426, Length=354, Percent_Identity=25.1412429378531, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI19913428, Length=354, Percent_Identity=24.8587570621469, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI50345984, Length=421, Percent_Identity=24.7030878859857, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4757810, Length=421, Percent_Identity=24.7030878859857, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1790170, Length=463, Percent_Identity=63.9308855291577, Blast_Score=617, Evalue=1e-178,
Organism=Escherichia coli, GI1788251, Length=306, Percent_Identity=29.7385620915033, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790172, Length=318, Percent_Identity=24.2138364779874, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=468, Percent_Identity=65.3846153846154, Blast_Score=630, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=353, Percent_Identity=27.4787535410765, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=355, Percent_Identity=24.7887323943662, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17570191, Length=352, Percent_Identity=24.4318181818182, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988080, Length=412, Percent_Identity=24.7572815533981, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=412, Percent_Identity=24.7572815533981, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71988074, Length=360, Percent_Identity=23.8888888888889, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=66.1572052401747, Blast_Score=628, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=353, Percent_Identity=26.628895184136, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6319370, Length=377, Percent_Identity=25.1989389920424, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320016, Length=253, Percent_Identity=27.6679841897233, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24638766, Length=466, Percent_Identity=65.6652360515021, Blast_Score=626, Evalue=1e-179,
Organism=Drosophila melanogaster, GI28574560, Length=484, Percent_Identity=61.9834710743802, Blast_Score=592, Evalue=1e-169,
Organism=Drosophila melanogaster, GI20129479, Length=343, Percent_Identity=27.6967930029155, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24583992, Length=321, Percent_Identity=27.7258566978193, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24583988, Length=350, Percent_Identity=26.2857142857143, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24583986, Length=350, Percent_Identity=26.2857142857143, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24583984, Length=350, Percent_Identity=26.2857142857143, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI281361666, Length=354, Percent_Identity=25.1412429378531, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646341, Length=354, Percent_Identity=25.1412429378531, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17136796, Length=354, Percent_Identity=25.1412429378531, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24658560, Length=409, Percent_Identity=23.7163814180929, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24638768, Length=93, Percent_Identity=48.3870967741936, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 53428; Mature: 53428

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSNHLKKLNRKGSNKNKRQMMAVGKVKQIVGPTLDIEFPPGQLPNILNAIKIIDPKDQ
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCHH
RELIAEVAMHLGDNQVRCIALSSTDGLVREAQAVDTEAPISIPVGSPTLGRLLNVLGQPI
HHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCH
DEMGAIENAEISPIHKASPTFEEQDTQGVIFETGIKVIDLLCPYTKGGKVGLFGGAGVGK
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCH
SVIVMELIHNIATHHGGYSVFCGIGERTREGNDLWLEMKESGILSKTSLVFGQMNEPPGA
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHEECCCCCCCC
RMRVGLTGLTMAEHFRDQEHQNVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLASE
EEEEECCHHHHHHHHCCHHHCEEEEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHH
IGSLQERITSTKHGSITSVQAIYVPADDYTDPAPASIFPHLDAATTLSRQIAELGIYPAV
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
DPLNSSSRILDPHVLGEEHYQVARQVQKVLQRYKDLQDIIAILGIDELSEEDQLTVSRAR
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHH
RIQKFLSQPFFVAETFTGKKGRFVKLPDTIKGFKMIVEGEMDNIPEQAFYMVGTIEEVFE
HHHHHHCCCEEEEEECCCCCCCEEECCCHHCCHHEEEECCCCCCCHHHHHHHHHHHHHHH
KAEQMK
HHHCCC
>Mature Secondary Structure
MNFSNHLKKLNRKGSNKNKRQMMAVGKVKQIVGPTLDIEFPPGQLPNILNAIKIIDPKDQ
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCHH
RELIAEVAMHLGDNQVRCIALSSTDGLVREAQAVDTEAPISIPVGSPTLGRLLNVLGQPI
HHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCH
DEMGAIENAEISPIHKASPTFEEQDTQGVIFETGIKVIDLLCPYTKGGKVGLFGGAGVGK
HHHCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCH
SVIVMELIHNIATHHGGYSVFCGIGERTREGNDLWLEMKESGILSKTSLVFGQMNEPPGA
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHEECCCCCCCC
RMRVGLTGLTMAEHFRDQEHQNVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLASE
EEEEECCHHHHHHHHCCHHHCEEEEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHH
IGSLQERITSTKHGSITSVQAIYVPADDYTDPAPASIFPHLDAATTLSRQIAELGIYPAV
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
DPLNSSSRILDPHVLGEEHYQVARQVQKVLQRYKDLQDIIAILGIDELSEEDQLTVSRAR
CCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHH
RIQKFLSQPFFVAETFTGKKGRFVKLPDTIKGFKMIVEGEMDNIPEQAFYMVGTIEEVFE
HHHHHHCCCEEEEEECCCCCCCEEECCCHHCCHHEEEECCCCCCCHHHHHHHHHHHHHHH
KAEQMK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA