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The map label for this gene is spoVc [H]

Identifier: 46447227

GI number: 46447227

Start: 1907781

End: 1908377

Strand: Reverse

Name: spoVc [H]

Synonym: pc1593

Alternate gene names: 46447227

Gene position: 1908377-1907781 (Counterclockwise)

Preceding gene: 46447228

Following gene: 46447226

Centisome position: 79.04

GC content: 33.84

Gene sequence:

>597_bases
ATGGGTTATCTTGTTATAAAAAGTTTAGCGAACAAGTTGGGATGGTCATTTAAAGAAGATAAACGTTTTAATGCTTTAAT
ATCGAAAGGAATGGTTGAAAACAAATCTGTCCACCTAATATTGCCACTTACCTATATGAATTTAAGTGGAACAGCTGTTA
AGCGTTATTTAGATTTTTTTAAATTTCCCATGACAAATCTATTTGTTGTGACAGATGATATATCTCTTTCATTTGGAAAG
TTGAAATTGAAAACAATGGGAAGTGCGGGTGGGCATAACGGTTTAAAAAGTGTAGAAACTCATTTAGGAACCTCTCACTA
TAATCGTTTAAAAATGGGAATTGGACATCCTGGCGAAAAAAATTTTGCTAGTTATGTTTTAGATGTTTTCACTCAAGAAG
AATTACAAGTTTTAGCGACTTTTGTTGATCGTGGAGTAGAAGTTTTACTCCGCTTAATTAAAGAAAGCGTTTCACAAGTG
ATGAACGCGGTTAACACAACTCCTAGCAAAGACAGATTAATGCCTTTGCCTAAAAAGCTCAAAAAAGCTTTAGAAAAGGA
GTCAATAGATTTAACAAAACCCCCTTTGCAGGGTTAG

Upstream 100 bases:

>100_bases
GTTAAGCTTTTTTTAAAATGTGACAACTTCAACTTCGCAATCTTATCTTTTTGTAGGGCTTGGTAATCCAGGGCTTCAAT
ATGAATTAACAAGGCATAAC

Downstream 100 bases:

>100_bases
GAGAATATACATGAGTCAAAAAGTACAAAACCTTTACGAAGGAATGTATGTCATTAGCGCAACGCTCAGTGATGATGCTC
GCCATAAGGCTTTAGATAGA

Product: peptidyl-tRNA hydrolase

Products: NA

Alternate protein names: PTH [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MGYLVIKSLANKLGWSFKEDKRFNALISKGMVENKSVHLILPLTYMNLSGTAVKRYLDFFKFPMTNLFVVTDDISLSFGK
LKLKTMGSAGGHNGLKSVETHLGTSHYNRLKMGIGHPGEKNFASYVLDVFTQEELQVLATFVDRGVEVLLRLIKESVSQV
MNAVNTTPSKDRLMPLPKKLKKALEKESIDLTKPPLQG

Sequences:

>Translated_198_residues
MGYLVIKSLANKLGWSFKEDKRFNALISKGMVENKSVHLILPLTYMNLSGTAVKRYLDFFKFPMTNLFVVTDDISLSFGK
LKLKTMGSAGGHNGLKSVETHLGTSHYNRLKMGIGHPGEKNFASYVLDVFTQEELQVLATFVDRGVEVLLRLIKESVSQV
MNAVNTTPSKDRLMPLPKKLKKALEKESIDLTKPPLQG
>Mature_197_residues
GYLVIKSLANKLGWSFKEDKRFNALISKGMVENKSVHLILPLTYMNLSGTAVKRYLDFFKFPMTNLFVVTDDISLSFGKL
KLKTMGSAGGHNGLKSVETHLGTSHYNRLKMGIGHPGEKNFASYVLDVFTQEELQVLATFVDRGVEVLLRLIKESVSQVM
NAVNTTPSKDRLMPLPKKLKKALEKESIDLTKPPLQG

Specific function: The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis [H]

COG id: COG0193

COG function: function code J; Peptidyl-tRNA hydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTH family [H]

Homologues:

Organism=Homo sapiens, GI50897284, Length=158, Percent_Identity=30.379746835443, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1787455, Length=163, Percent_Identity=31.2883435582822, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001328
- InterPro:   IPR018171 [H]

Pfam domain/function: PF01195 Pept_tRNA_hydro [H]

EC number: =3.1.1.29 [H]

Molecular weight: Translated: 22117; Mature: 21986

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS01196 PEPT_TRNA_HYDROL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYLVIKSLANKLGWSFKEDKRFNALISKGMVENKSVHLILPLTYMNLSGTAVKRYLDFF
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHH
KFPMTNLFVVTDDISLSFGKLKLKTMGSAGGHNGLKSVETHLGTSHYNRLKMGIGHPGEK
HCCCCEEEEEECCCEECCCEEEEEECCCCCCCCCHHHHHHHHCHHHHHHHHCCCCCCCCH
NFASYVLDVFTQEELQVLATFVDRGVEVLLRLIKESVSQVMNAVNTTPSKDRLMPLPKKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
KKALEKESIDLTKPPLQG
HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GYLVIKSLANKLGWSFKEDKRFNALISKGMVENKSVHLILPLTYMNLSGTAVKRYLDFF
CHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHH
KFPMTNLFVVTDDISLSFGKLKLKTMGSAGGHNGLKSVETHLGTSHYNRLKMGIGHPGEK
HCCCCEEEEEECCCEECCCEEEEEECCCCCCCCCHHHHHHHHCHHHHHHHHCCCCCCCCH
NFASYVLDVFTQEELQVLATFVDRGVEVLLRLIKESVSQVMNAVNTTPSKDRLMPLPKKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
KKALEKESIDLTKPPLQG
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA