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The map label for this gene is clpB [H]

Identifier: 46447192

GI number: 46447192

Start: 1866089

End: 1868032

Strand: Reverse

Name: clpB [H]

Synonym: pc1558

Alternate gene names: 46447192

Gene position: 1868032-1866089 (Counterclockwise)

Preceding gene: 46447193

Following gene: 46447191

Centisome position: 77.37

GC content: 33.33

Gene sequence:

>1944_bases
ATGATGCCTTGGAATATATCGATTTTACCCTCTTTTATCCTTTTTAACACACATTCAACTTTAGTTAGTCCACCTTCTTC
CCCCTTACAAAATTTGCGTTCACTTGAAGATTTAGCAGAATTGTTGTTGTCTGAAGAATGGGGGATGGATAAATGGGAAA
AATGGCAAACACAACTTACTCAATTTATACGTGAGCATTCACAAGATAAAGAAAATTTCGATCGATTTTTGTCAAATATT
GTTTTTGGTATGGTCCAAAAAGACCTGCCAAAAGCCTTGAATTTTCTTTCTGAAGTCATCGATTTAGAATTAATGAATGA
AATTGCTCATTTTAAAAGTCAACAAGAAGAACTTCCTCTATTTCGCAGTGCTTTCGAATCCGCTTTTTTAAGAGCTTCCT
TATGTACACAACGTAATACCACAGCAATGGCTGATAAATTTTACGGAGAATGGAAACGTTTTCGCCCTATTGCTATTTAT
TTTTTCCCAAACTTAATCAATCTCTTTTTAGGTGCCTTCAATTTTTTAGATTCGCATAAAAAATTTACTACTTTATGGGA
TAAATATTTATTACTGGATATTGTTTATAAGTTTTTTGCTATTCCTTTTTTTTTGGTACAAGTATTACAGCCGATTGTTG
GGGTGACAGTAAGAGTCTATGCAATTGCAGCAGCGATTATCGTCTGTGGAGGGGTTTTGGCCGCTTGCTATCAAAAGTGG
CTAAAGCCTTTACCTGATGAAATCGTGAATTGCACTAATTTAGATAAACAGTTTGAAAGAGGGAATATAGATCCTAAAGT
TGGCATGACTAAAACAGTTAATCAAATCATTTCCGCATTGCTAACAGGATCTAATATCCTTCTGGTGGGGAAGTCTGGAG
ATGGAAAAACTGCTGTTACACAAAGGCTTATCCAACTCAAACATGAAAAGAAGTTACCCCAAGAGTTGCTTAAAAGAACG
AACTATGAAGTTGATTGCGGGTTATTAATTTCGAATTATAGTTTTGGACATTCAGAATTGATTAATCAAATTAAAAATCA
AATTGACGGATTTGAAGATCAAATTCTATTCCATTTTGATGAACTCGATCAATTAGCTACCAATGATTCTGCTTTTAAAG
CTTTCAAGAAAAGGTTTTTGACTGATCGCCCAAGTCCTTTATTTATTGCAACCACAACTTTTGAAAAATTACAGCAAATA
GAAAGTCTCGATACTGATGGGGCATTTAGAAGAAAAATTGTCAAAATTATTGTTGATGGAGATGACGAAAATCAAAATCG
ACACATGATTCAAGAATTGATTAACCGTACAGCTATCGACATTCCTATTCAAGATGAAGCGGTTGAAAAAGTTTTAGAGC
TCTCCAAGCGGCAAAATTATTTACCAAATATTGGAGCACCGGCAAAAGCTATTAAATTACTGGAAGATGCAATTGGTAAA
TGTCGATGGGTTTATAGCAAAGACTTTACTTTGCTTGAATTAGAACTTGCTAAGCAAGAGCTTCAACATATGAATTCTCG
TCAAAGTAGAGCGATTAGAGAAACTGCTTTAGAAATGGAAACTTATATCAACCTAAAGAGACGCATAGAAGAGTTAGAAA
AAAAAGAAAAGAAATTAAAGGACGAAATTCAAAATATTAAATTTTTAATTTCACAACAATTATCGTTAAAAGAAAATTAT
TTTAGATTAACACATCAACTTGCCAAAGTATTTTCACAAAATAGTTCGATTAGAGAGGGAGAGAATAGATATACGGGAAA
GAAGGAAAAAGAGCAAAAAATTTACCTATTATCTTATTTTTATGCTATTCATGCCTTTAAATCGGCTTTACAACAAAAAA
TCAATACTATCCATTCTCAACTGCACATCCAAGTAGATGCTTCACTGATTCAACAAGTTTTTAATGAATCAGTAGCACTG
TTGCCCGACACGCCTATTTTATAA

Upstream 100 bases:

>100_bases
AACAATTCCTTTTGGATAAAATTTTCCAACAGATATGATAGAAAATCACATTTAAAAAACTTTTGTAATTTCCCATATTT
AAACTTGATTAGAAGAGAAA

Downstream 100 bases:

>100_bases
ACTTGATAAATGAGAAAAAAATGAATCAAAGAACAGGAATTTTACTTGTTAACCTTGGAACACCTAAAACTCCTCGACCT
AAAGATGTCTATCGTTATTT

Product: putative heat shock protein ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MMPWNISILPSFILFNTHSTLVSPPSSPLQNLRSLEDLAELLLSEEWGMDKWEKWQTQLTQFIREHSQDKENFDRFLSNI
VFGMVQKDLPKALNFLSEVIDLELMNEIAHFKSQQEELPLFRSAFESAFLRASLCTQRNTTAMADKFYGEWKRFRPIAIY
FFPNLINLFLGAFNFLDSHKKFTTLWDKYLLLDIVYKFFAIPFFLVQVLQPIVGVTVRVYAIAAAIIVCGGVLAACYQKW
LKPLPDEIVNCTNLDKQFERGNIDPKVGMTKTVNQIISALLTGSNILLVGKSGDGKTAVTQRLIQLKHEKKLPQELLKRT
NYEVDCGLLISNYSFGHSELINQIKNQIDGFEDQILFHFDELDQLATNDSAFKAFKKRFLTDRPSPLFIATTTFEKLQQI
ESLDTDGAFRRKIVKIIVDGDDENQNRHMIQELINRTAIDIPIQDEAVEKVLELSKRQNYLPNIGAPAKAIKLLEDAIGK
CRWVYSKDFTLLELELAKQELQHMNSRQSRAIRETALEMETYINLKRRIEELEKKEKKLKDEIQNIKFLISQQLSLKENY
FRLTHQLAKVFSQNSSIREGENRYTGKKEKEQKIYLLSYFYAIHAFKSALQQKINTIHSQLHIQVDASLIQQVFNESVAL
LPDTPIL

Sequences:

>Translated_647_residues
MMPWNISILPSFILFNTHSTLVSPPSSPLQNLRSLEDLAELLLSEEWGMDKWEKWQTQLTQFIREHSQDKENFDRFLSNI
VFGMVQKDLPKALNFLSEVIDLELMNEIAHFKSQQEELPLFRSAFESAFLRASLCTQRNTTAMADKFYGEWKRFRPIAIY
FFPNLINLFLGAFNFLDSHKKFTTLWDKYLLLDIVYKFFAIPFFLVQVLQPIVGVTVRVYAIAAAIIVCGGVLAACYQKW
LKPLPDEIVNCTNLDKQFERGNIDPKVGMTKTVNQIISALLTGSNILLVGKSGDGKTAVTQRLIQLKHEKKLPQELLKRT
NYEVDCGLLISNYSFGHSELINQIKNQIDGFEDQILFHFDELDQLATNDSAFKAFKKRFLTDRPSPLFIATTTFEKLQQI
ESLDTDGAFRRKIVKIIVDGDDENQNRHMIQELINRTAIDIPIQDEAVEKVLELSKRQNYLPNIGAPAKAIKLLEDAIGK
CRWVYSKDFTLLELELAKQELQHMNSRQSRAIRETALEMETYINLKRRIEELEKKEKKLKDEIQNIKFLISQQLSLKENY
FRLTHQLAKVFSQNSSIREGENRYTGKKEKEQKIYLLSYFYAIHAFKSALQQKINTIHSQLHIQVDASLIQQVFNESVAL
LPDTPIL
>Mature_647_residues
MMPWNISILPSFILFNTHSTLVSPPSSPLQNLRSLEDLAELLLSEEWGMDKWEKWQTQLTQFIREHSQDKENFDRFLSNI
VFGMVQKDLPKALNFLSEVIDLELMNEIAHFKSQQEELPLFRSAFESAFLRASLCTQRNTTAMADKFYGEWKRFRPIAIY
FFPNLINLFLGAFNFLDSHKKFTTLWDKYLLLDIVYKFFAIPFFLVQVLQPIVGVTVRVYAIAAAIIVCGGVLAACYQKW
LKPLPDEIVNCTNLDKQFERGNIDPKVGMTKTVNQIISALLTGSNILLVGKSGDGKTAVTQRLIQLKHEKKLPQELLKRT
NYEVDCGLLISNYSFGHSELINQIKNQIDGFEDQILFHFDELDQLATNDSAFKAFKKRFLTDRPSPLFIATTTFEKLQQI
ESLDTDGAFRRKIVKIIVDGDDENQNRHMIQELINRTAIDIPIQDEAVEKVLELSKRQNYLPNIGAPAKAIKLLEDAIGK
CRWVYSKDFTLLELELAKQELQHMNSRQSRAIRETALEMETYINLKRRIEELEKKEKKLKDEIQNIKFLISQQLSLKENY
FRLTHQLAKVFSQNSSIREGENRYTGKKEKEQKIYLLSYFYAIHAFKSALQQKINTIHSQLHIQVDASLIQQVFNESVAL
LPDTPIL

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

None

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 74892; Mature: 74892

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]