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The map label for this gene is prpC [H]

Identifier: 46446354

GI number: 46446354

Start: 875458

End: 876237

Strand: Direct

Name: prpC [H]

Synonym: pc0720

Alternate gene names: 46446354

Gene position: 875458-876237 (Clockwise)

Preceding gene: 46446353

Following gene: 46446355

Centisome position: 36.26

GC content: 37.44

Gene sequence:

>780_bases
ATGGCTCTTCAAGCAATGTTCTATAAAACCTTAGTTTATGGCATCTCGGATGTTGGTCTTGTTAGGCAAAATAATGAAGA
TTCTTGGGGACAAATTCTAGAAGATCATTTTTTTGTTTTAGCAGATGGAATGGGCGGACACCGTGCCGGCGAAGTTGCTT
CAAAGGAAGCTGTCAGCCAACTTTGCGCAAAGTTTAAAGAAAAATTCAGTCGTTGCTCAAAAGATATCAAATCTTCTTTC
GAAATGATCAAAGAATCCATTCAGGAAGTCAACTACAACATTTATAAAATGGGCCGCGAACAAGAGATACTTCGTGGAAT
GGGGACAACATTGTGCTGTGTTTGCCTACATTCGGAAGGGGTGATTTTTGGACACGTAGGAGATAGTCGAATTTATCGAT
TGAGAGATAACAATTTAAAGCAAATTACTCAAGATCATTCTCTGCTTCGAGAACTTATTGAATTAGGTCAGTTAAGCGAA
CATCAAGCGTGCGAATTTGCTTATAAAAATATCATCACTAAGGCAATTGGTACAGGACCTTTTGTTGAACCTTCCCTCAA
AATAGATTCCATTGAAGTAGGTGATGTTATTTTGATGTGTACAGATGGATTGAGTGATTTATTAAGCATTCAAGACATTC
AACAAATTTTATCAGATACTCCTGATGATGAAGTTACCAAAAAATTGGTAAAAGTGGCGAAATCGAGAGGAGGACACGAT
AACATCACAGTTGTTGTTATTAAAGTTCAGGGAAAATATGAATCGGCGAGTCTATCTTGA

Upstream 100 bases:

>100_bases
TGATTAATTTCGAATCAGTCTTAAAAGTATCTCAACGGTATTTTTTGTTAATAGAGATATTAATGATTTTACGACCCCAT
TTTAGGTTTTACCTTTTATT

Downstream 100 bases:

>100_bases
TTGCAATTCTAGCACCGCGATCGATCCTCGCGTTTTGAAAGTTCTGATCCAAGAACTTCAAGAAGAAGAGGGAAATCCTT
CAAGCGTTCATTATCACGGG

Product: putative serine/threonine phosphoprotein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MALQAMFYKTLVYGISDVGLVRQNNEDSWGQILEDHFFVLADGMGGHRAGEVASKEAVSQLCAKFKEKFSRCSKDIKSSF
EMIKESIQEVNYNIYKMGREQEILRGMGTTLCCVCLHSEGVIFGHVGDSRIYRLRDNNLKQITQDHSLLRELIELGQLSE
HQACEFAYKNIITKAIGTGPFVEPSLKIDSIEVGDVILMCTDGLSDLLSIQDIQQILSDTPDDEVTKKLVKVAKSRGGHD
NITVVVIKVQGKYESASLS

Sequences:

>Translated_259_residues
MALQAMFYKTLVYGISDVGLVRQNNEDSWGQILEDHFFVLADGMGGHRAGEVASKEAVSQLCAKFKEKFSRCSKDIKSSF
EMIKESIQEVNYNIYKMGREQEILRGMGTTLCCVCLHSEGVIFGHVGDSRIYRLRDNNLKQITQDHSLLRELIELGQLSE
HQACEFAYKNIITKAIGTGPFVEPSLKIDSIEVGDVILMCTDGLSDLLSIQDIQQILSDTPDDEVTKKLVKVAKSRGGHD
NITVVVIKVQGKYESASLS
>Mature_258_residues
ALQAMFYKTLVYGISDVGLVRQNNEDSWGQILEDHFFVLADGMGGHRAGEVASKEAVSQLCAKFKEKFSRCSKDIKSSFE
MIKESIQEVNYNIYKMGREQEILRGMGTTLCCVCLHSEGVIFGHVGDSRIYRLRDNNLKQITQDHSLLRELIELGQLSEH
QACEFAYKNIITKAIGTGPFVEPSLKIDSIEVGDVILMCTDGLSDLLSIQDIQQILSDTPDDEVTKKLVKVAKSRGGHDN
ITVVVIKVQGKYESASLS

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 28842; Mature: 28711

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQAMFYKTLVYGISDVGLVRQNNEDSWGQILEDHFFVLADGMGGHRAGEVASKEAVSQ
CCHHHHHHHHHHHCCHHHHHEECCCCCHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHH
LCAKFKEKFSRCSKDIKSSFEMIKESIQEVNYNIYKMGREQEILRGMGTTLCCVCLHSEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHCCHHHHHHEECCCC
VIFGHVGDSRIYRLRDNNLKQITQDHSLLRELIELGQLSEHQACEFAYKNIITKAIGTGP
EEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
FVEPSLKIDSIEVGDVILMCTDGLSDLLSIQDIQQILSDTPDDEVTKKLVKVAKSRGGHD
CCCCCCEECCEEECCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
NITVVVIKVQGKYESASLS
CEEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
ALQAMFYKTLVYGISDVGLVRQNNEDSWGQILEDHFFVLADGMGGHRAGEVASKEAVSQ
CHHHHHHHHHHHCCHHHHHEECCCCCHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHH
LCAKFKEKFSRCSKDIKSSFEMIKESIQEVNYNIYKMGREQEILRGMGTTLCCVCLHSEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHCCHHHHHHEECCCC
VIFGHVGDSRIYRLRDNNLKQITQDHSLLRELIELGQLSEHQACEFAYKNIITKAIGTGP
EEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
FVEPSLKIDSIEVGDVILMCTDGLSDLLSIQDIQQILSDTPDDEVTKKLVKVAKSRGGHD
CCCCCCEECCEEECCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
NITVVVIKVQGKYESASLS
CEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]