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The map label for this gene is nusG [H]

Identifier: 46446233

GI number: 46446233

Start: 735041

End: 735415

Strand: Direct

Name: nusG [H]

Synonym: pc0599

Alternate gene names: 46446233

Gene position: 735041-735415 (Clockwise)

Preceding gene: 46446232

Following gene: 46446234

Centisome position: 30.44

GC content: 33.87

Gene sequence:

>375_bases
TTGTGGCCTGGTTATTTGCTCATCAAAATGAATCTTAGTGACGAATCTTGGCAATATGTAAAAAATACTAATGGTGTCAT
TGATTTTCTAGGTGGAGATAAACCAACGCCTCTGACAGATTTCGAAGTGGGTGAAATTTTAAAAGATCTAGAAGATAAAA
AACGGAAAATTACCCAGAAACATAAATTTGAAGTTGGTGATCGTGTTAAAATTACCGACGGTGTTTTTGTTAATTTTATT
GGAACGGTAACTGAAGTATTTCATGATAAAGGCCGTTTAAGTGTCTTGGTATCAATATTTGGCCGTGATACGCGAGTAGA
TGATTTAGAATTTGTTCAAGTTGAAGAAATTTCTGATGATGCTGAAATCACTTAA

Upstream 100 bases:

>100_bases
TCGAGTTAAAAGGGATGTCTGGTGAAATCGAGCAGATTTTGCTTCCAACTGAAAATGTGTCAGAAGTTAAAAAGGTCAGC
AACATGTTGTTGAAAAACGT

Downstream 100 bases:

>100_bases
TTTTAAATTTAGATTTAAGGTTATTGTTTTTTGAAATTTTAACAAAAAATCAATAAAACTAAAAAAACGCTAGAATTTTC
TAGTCGTTTTTTGTATACTT

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MWPGYLLIKMNLSDESWQYVKNTNGVIDFLGGDKPTPLTDFEVGEILKDLEDKKRKITQKHKFEVGDRVKITDGVFVNFI
GTVTEVFHDKGRLSVLVSIFGRDTRVDDLEFVQVEEISDDAEIT

Sequences:

>Translated_124_residues
MWPGYLLIKMNLSDESWQYVKNTNGVIDFLGGDKPTPLTDFEVGEILKDLEDKKRKITQKHKFEVGDRVKITDGVFVNFI
GTVTEVFHDKGRLSVLVSIFGRDTRVDDLEFVQVEEISDDAEIT
>Mature_124_residues
MWPGYLLIKMNLSDESWQYVKNTNGVIDFLGGDKPTPLTDFEVGEILKDLEDKKRKITQKHKFEVGDRVKITDGVFVNFI
GTVTEVFHDKGRLSVLVSIFGRDTRVDDLEFVQVEEISDDAEIT

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=117, Percent_Identity=44.4444444444444, Blast_Score=96, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 14181; Mature: 14181

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWPGYLLIKMNLSDESWQYVKNTNGVIDFLGGDKPTPLTDFEVGEILKDLEDKKRKITQK
CCCCEEEEEEECCCCCHHEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HKFEVGDRVKITDGVFVNFIGTVTEVFHDKGRLSVLVSIFGRDTRVDDLEFVQVEEISDD
HCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEECCCCC
AEIT
CCCC
>Mature Secondary Structure
MWPGYLLIKMNLSDESWQYVKNTNGVIDFLGGDKPTPLTDFEVGEILKDLEDKKRKITQK
CCCCEEEEEEECCCCCHHEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HKFEVGDRVKITDGVFVNFIGTVTEVFHDKGRLSVLVSIFGRDTRVDDLEFVQVEEISDD
HCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEECCCCC
AEIT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10871362; 10684935 [H]