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The map label for this gene is nuoG [H]

Identifier: 46446199

GI number: 46446199

Start: 698148

End: 700469

Strand: Direct

Name: nuoG [H]

Synonym: pc0565

Alternate gene names: 46446199

Gene position: 698148-700469 (Clockwise)

Preceding gene: 46446198

Following gene: 46446200

Centisome position: 28.92

GC content: 37.9

Gene sequence:

>2322_bases
GTGACTGTGGAAATGATGATTAACTTAATAATCGATGGAAAGGAATTAAGTGTTCCAAAGGGAACAACTGTTTATCATGC
CGCCAAACAACTAGGCATTGACATTCCTATTTTTTGTTACCAAGATCGCATGCCTCCTTTTGGTGCTTGTCGAATGTGTT
TGGTAGAAGTGGAAAAAATGAATAAATTGCAAGCATCATGCGCATTAGAAGTGGCTGAAGGAATGGTTGTAAAAACGCAA
AGTACTGTTGCAAAAGAGGGACGGGAAGGGATTTTAGAACTTTTACTTATTAATCATCCTTTAGATTGCCCTATTTGCGA
TAAAGGGGGAGAATGTCCTCTGCAAGATCAAACTTTAAAACATGGACCTGGAGAAAGCCGATTTTACGAAGAAAAAAGAC
ATTTTACTAAAGCTCTTCCTCTAGGACCAACTTTAATGTTAGATCGGGAACGTTGTATTGTGTGTGCCCGTTGTACACGA
TTTGGTGATATTGTTGCGGGCGATCATGCTTTAGAAATGAAAGAACGTGGTTTTCGAACTGAAGTAGGTACACCGGGCAA
TCGTCTTGTGGAGTCTAAATTTATTGGGAATACCATTTCTATTTGCCCAGTTGGTGCTTTAACGAGTCAAGTTTATAGAT
TTCGGGCTAGACCATGGGACAACCATTCTATTCCTAGTACGTGTACATTATGCCCTGTAGGATGTAGTTTAAACATTGAT
TCGAGAGATGGACAAATTGTTCGGACCCGTTCGAGAGAAAATAAATTAGTCAATGATATCTGGCTTTGCGATAAAGGTTG
GTTTGGTTATGAATTTGTTTCTAACGCAAATCGCTTACAACAGCCTTTAATTCGAAGAGATGGAAAATTAACTCCTGCTA
GTTGGGAAGAAGCTTTAAATTTAATCGTTTCTCAAATTAAATTTGCAAAACCAACAAAAAAAATTGCGGGATTAGGGGGA
AATCCTTTAACAACGGAAGAAAATTATCTTTTTCAACGGTTAATTCGTGAAGTTGCAGAGGTGAATCATGTTGACCATCG
AATTGGAACTCCTCATTTTGATTCTGAGCAAGAAAGATTATCTCCAGGGATGGAAATTTCTCTTGGTGAATGCGAATCTC
TTTCATTTGTGATCTTATTAGGATTAGACTTAACAGAAGAATTTCCCCTTATTTGGCTTCGCTTAAAACAAGCGATTAAC
AAAGGAGCTAAAGTTTTATTTATGGGGAATTTTTCCCCCGAAATAGCGAGTTATTTAACAAAAATAGTTCTACATCCGCC
AGGAAAAGAACTAGAGAATTGGGATGAGAACTTACCTCTTATTGACGAATGGGTTTCTCAAGGAAAATCAGGAGCGATAT
TTGTTGGGCAACAATATTTGATAAATTTCAATAGGCCATTGATATTAGACAAGCTATGGTCATTCCGACAGTCACACTCT
AATCTAACCTTGAATCTCTTAGAAGGCTCAGGGAATTCACAGGGAGCCAGGTTTGCTGGAATGCGGCCTGATTTAGGACC
TTTAAATCAAAAGATTGAAGAACCTGGATTACATACTTTAGCTATTCTCGAAGCAGCTGCTAAAAAAGATTGGGAATTTC
TCTATGTGGTTGGCGCTAATCTTGCCAAGAAATATCCAGCAAAACTGTGGCGATCTGCTCGGGAAAATATAAAATTTATG
GTTGTGCAAGATCTGTTTTTAACGGAAACAGCATTAGATGCTGATGTTGTGCTGCCTTCACTATCATTTATCGAAAAATC
AGGGACATTTATTAATATCGAAAACAGAATTCAGACACTGCATCAAGGAAAAGAAATTCCTGAAAATAGCTTTAGTGATG
CATCGATTTTTATGGCTATCGCAGAAAAACTGGGAATTCAATTATCTTTTGAACCTGCTTTTTTAGACGCTCTTTCTCAA
ACCAAGGTATTTCATACCTGTGAATTGAGAACATCATTGCCGCTATCCGAGCCCGTCTCTAATGAAAAGTTAAAAGCTGT
CTTTGCCCCTGCTTTATTTGATGAAGGGATTCGCATGAAACATGATCCTCATCTCATCCAGTTAGTTAAAGAACCTCGTT
TACGAATGCATCCAAATGAGGCTAAAAAGAGAGGAATCATGCAGGGTGATACAGTTCGTTTGACGACAAATAAAGGATCT
CTTCAGGCAAAAATAAAATGGGATGGAAATGTAGCGGAACAGACAGTGATTATTCCTTTAGGATTTGACCTTATTTCCGC
TCATGATTTAGATAGTAACCTCATCAATGGATTGCCAATCGATATTCAACTAATTGAATCACAAAAAGAAGAGTCTCTAT
GA

Upstream 100 bases:

>100_bases
GATTAGAGAATTCAGAGGCGAATTTGAATCTTATATTATGCGTAACATTCATGCTGATAAACCTCCTGAAATGAAAATTA
CTTATCCTTATTTGTAGGTA

Downstream 100 bases:

>100_bases
TTGACGACTTAATCATCATTCTTATTAAAAGTGCTGTTGTCATTCTTTTATTATTTACAGCAGCTGCCTATATGACATTT
TTAGAACGTATTGTCATGGC

Product: putative NADH-ubiquinone oxidoreductase chain G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 773; Mature: 772

Protein sequence:

>773_residues
MTVEMMINLIIDGKELSVPKGTTVYHAAKQLGIDIPIFCYQDRMPPFGACRMCLVEVEKMNKLQASCALEVAEGMVVKTQ
STVAKEGREGILELLLINHPLDCPICDKGGECPLQDQTLKHGPGESRFYEEKRHFTKALPLGPTLMLDRERCIVCARCTR
FGDIVAGDHALEMKERGFRTEVGTPGNRLVESKFIGNTISICPVGALTSQVYRFRARPWDNHSIPSTCTLCPVGCSLNID
SRDGQIVRTRSRENKLVNDIWLCDKGWFGYEFVSNANRLQQPLIRRDGKLTPASWEEALNLIVSQIKFAKPTKKIAGLGG
NPLTTEENYLFQRLIREVAEVNHVDHRIGTPHFDSEQERLSPGMEISLGECESLSFVILLGLDLTEEFPLIWLRLKQAIN
KGAKVLFMGNFSPEIASYLTKIVLHPPGKELENWDENLPLIDEWVSQGKSGAIFVGQQYLINFNRPLILDKLWSFRQSHS
NLTLNLLEGSGNSQGARFAGMRPDLGPLNQKIEEPGLHTLAILEAAAKKDWEFLYVVGANLAKKYPAKLWRSARENIKFM
VVQDLFLTETALDADVVLPSLSFIEKSGTFINIENRIQTLHQGKEIPENSFSDASIFMAIAEKLGIQLSFEPAFLDALSQ
TKVFHTCELRTSLPLSEPVSNEKLKAVFAPALFDEGIRMKHDPHLIQLVKEPRLRMHPNEAKKRGIMQGDTVRLTTNKGS
LQAKIKWDGNVAEQTVIIPLGFDLISAHDLDSNLINGLPIDIQLIESQKEESL

Sequences:

>Translated_773_residues
MTVEMMINLIIDGKELSVPKGTTVYHAAKQLGIDIPIFCYQDRMPPFGACRMCLVEVEKMNKLQASCALEVAEGMVVKTQ
STVAKEGREGILELLLINHPLDCPICDKGGECPLQDQTLKHGPGESRFYEEKRHFTKALPLGPTLMLDRERCIVCARCTR
FGDIVAGDHALEMKERGFRTEVGTPGNRLVESKFIGNTISICPVGALTSQVYRFRARPWDNHSIPSTCTLCPVGCSLNID
SRDGQIVRTRSRENKLVNDIWLCDKGWFGYEFVSNANRLQQPLIRRDGKLTPASWEEALNLIVSQIKFAKPTKKIAGLGG
NPLTTEENYLFQRLIREVAEVNHVDHRIGTPHFDSEQERLSPGMEISLGECESLSFVILLGLDLTEEFPLIWLRLKQAIN
KGAKVLFMGNFSPEIASYLTKIVLHPPGKELENWDENLPLIDEWVSQGKSGAIFVGQQYLINFNRPLILDKLWSFRQSHS
NLTLNLLEGSGNSQGARFAGMRPDLGPLNQKIEEPGLHTLAILEAAAKKDWEFLYVVGANLAKKYPAKLWRSARENIKFM
VVQDLFLTETALDADVVLPSLSFIEKSGTFINIENRIQTLHQGKEIPENSFSDASIFMAIAEKLGIQLSFEPAFLDALSQ
TKVFHTCELRTSLPLSEPVSNEKLKAVFAPALFDEGIRMKHDPHLIQLVKEPRLRMHPNEAKKRGIMQGDTVRLTTNKGS
LQAKIKWDGNVAEQTVIIPLGFDLISAHDLDSNLINGLPIDIQLIESQKEESL
>Mature_772_residues
TVEMMINLIIDGKELSVPKGTTVYHAAKQLGIDIPIFCYQDRMPPFGACRMCLVEVEKMNKLQASCALEVAEGMVVKTQS
TVAKEGREGILELLLINHPLDCPICDKGGECPLQDQTLKHGPGESRFYEEKRHFTKALPLGPTLMLDRERCIVCARCTRF
GDIVAGDHALEMKERGFRTEVGTPGNRLVESKFIGNTISICPVGALTSQVYRFRARPWDNHSIPSTCTLCPVGCSLNIDS
RDGQIVRTRSRENKLVNDIWLCDKGWFGYEFVSNANRLQQPLIRRDGKLTPASWEEALNLIVSQIKFAKPTKKIAGLGGN
PLTTEENYLFQRLIREVAEVNHVDHRIGTPHFDSEQERLSPGMEISLGECESLSFVILLGLDLTEEFPLIWLRLKQAINK
GAKVLFMGNFSPEIASYLTKIVLHPPGKELENWDENLPLIDEWVSQGKSGAIFVGQQYLINFNRPLILDKLWSFRQSHSN
LTLNLLEGSGNSQGARFAGMRPDLGPLNQKIEEPGLHTLAILEAAAKKDWEFLYVVGANLAKKYPAKLWRSARENIKFMV
VQDLFLTETALDADVVLPSLSFIEKSGTFINIENRIQTLHQGKEIPENSFSDASIFMAIAEKLGIQLSFEPAFLDALSQT
KVFHTCELRTSLPLSEPVSNEKLKAVFAPALFDEGIRMKHDPHLIQLVKEPRLRMHPNEAKKRGIMQGDTVRLTTNKGSL
QAKIKWDGNVAEQTVIIPLGFDLISAHDLDSNLINGLPIDIQLIESQKEESL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG3383

COG function: function code R; Uncharacterized anaerobic dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=636, Percent_Identity=30.8176100628931, Blast_Score=286, Evalue=4e-77,
Organism=Escherichia coli, GI145693161, Length=670, Percent_Identity=27.3134328358209, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI3868721, Length=197, Percent_Identity=30.4568527918782, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788534, Length=194, Percent_Identity=24.2268041237113, Blast_Score=66, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17565758, Length=647, Percent_Identity=31.839258114374, Blast_Score=282, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI32566231, Length=621, Percent_Identity=32.3671497584541, Blast_Score=277, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI193209088, Length=259, Percent_Identity=42.0849420849421, Blast_Score=208, Evalue=8e-54,
Organism=Drosophila melanogaster, GI24640559, Length=650, Percent_Identity=32, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24640557, Length=650, Percent_Identity=32, Blast_Score=273, Evalue=3e-73,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 86612; Mature: 86481

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEMMINLIIDGKELSVPKGTTVYHAAKQLGIDIPIFCYQDRMPPFGACRMCLVEVEKM
CCHHEEEEEEECCCEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHH
NKLQASCALEVAEGMVVKTQSTVAKEGREGILELLLINHPLDCPICDKGGECPLQDQTLK
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHC
HGPGESRFYEEKRHFTKALPLGPTLMLDRERCIVCARCTRFGDIVAGDHALEMKERGFRT
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHEEEHHHHHCCCEECCCHHHHHHHCCCCC
EVGTPGNRLVESKFIGNTISICPVGALTSQVYRFRARPWDNHSIPSTCTLCPVGCSLNID
CCCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEC
SRDGQIVRTRSRENKLVNDIWLCDKGWFGYEFVSNANRLQQPLIRRDGKLTPASWEEALN
CCCCCEEEECCCCCCHHHHEEEECCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHH
LIVSQIKFAKPTKKIAGLGGNPLTTEENYLFQRLIREVAEVNHVDHRIGTPHFDSEQERL
HHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
SPGMEISLGECESLSFVILLGLDLTEEFPLIWLRLKQAINKGAKVLFMGNFSPEIASYLT
CCCCEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
KIVLHPPGKELENWDENLPLIDEWVSQGKSGAIFVGQQYLINFNRPLILDKLWSFRQSHS
HHEECCCCCHHHCCCCCCCHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHCCC
NLTLNLLEGSGNSQGARFAGMRPDLGPLNQKIEEPGLHTLAILEAAAKKDWEFLYVVGAN
CEEEEEEECCCCCCCCEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCH
LAKKYPAKLWRSARENIKFMVVQDLFLTETALDADVVLPSLSFIEKSGTFINIENRIQTL
HHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCHHHHHCCHHHHHCCCCEEEEHHHHHHH
HQGKEIPENSFSDASIFMAIAEKLGIQLSFEPAFLDALSQTKVFHTCELRTSLPLSEPVS
HCCCCCCCCCCCHHHHHHHHHHHHCCEEEECHHHHHHHHHCCEEEEEECCCCCCCCCCCC
NEKLKAVFAPALFDEGIRMKHDPHLIQLVKEPRLRMHPNEAKKRGIMQGDTVRLTTNKGS
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEECCCC
LQAKIKWDGNVAEQTVIIPLGFDLISAHDLDSNLINGLPIDIQLIESQKEESL
EEEEEEECCCCCCEEEEEEECCHHHCCCCCCCHHHCCCCEEEEEECCHHHCCC
>Mature Secondary Structure 
TVEMMINLIIDGKELSVPKGTTVYHAAKQLGIDIPIFCYQDRMPPFGACRMCLVEVEKM
CHHEEEEEEECCCEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHH
NKLQASCALEVAEGMVVKTQSTVAKEGREGILELLLINHPLDCPICDKGGECPLQDQTLK
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHC
HGPGESRFYEEKRHFTKALPLGPTLMLDRERCIVCARCTRFGDIVAGDHALEMKERGFRT
CCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHEEEHHHHHCCCEECCCHHHHHHHCCCCC
EVGTPGNRLVESKFIGNTISICPVGALTSQVYRFRARPWDNHSIPSTCTLCPVGCSLNID
CCCCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEC
SRDGQIVRTRSRENKLVNDIWLCDKGWFGYEFVSNANRLQQPLIRRDGKLTPASWEEALN
CCCCCEEEECCCCCCHHHHEEEECCCCCCHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHH
LIVSQIKFAKPTKKIAGLGGNPLTTEENYLFQRLIREVAEVNHVDHRIGTPHFDSEQERL
HHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
SPGMEISLGECESLSFVILLGLDLTEEFPLIWLRLKQAINKGAKVLFMGNFSPEIASYLT
CCCCEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
KIVLHPPGKELENWDENLPLIDEWVSQGKSGAIFVGQQYLINFNRPLILDKLWSFRQSHS
HHEECCCCCHHHCCCCCCCHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHCCC
NLTLNLLEGSGNSQGARFAGMRPDLGPLNQKIEEPGLHTLAILEAAAKKDWEFLYVVGAN
CEEEEEEECCCCCCCCEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCH
LAKKYPAKLWRSARENIKFMVVQDLFLTETALDADVVLPSLSFIEKSGTFINIENRIQTL
HHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCHHHHHCCHHHHHCCCCEEEEHHHHHHH
HQGKEIPENSFSDASIFMAIAEKLGIQLSFEPAFLDALSQTKVFHTCELRTSLPLSEPVS
HCCCCCCCCCCCHHHHHHHHHHHHCCEEEECHHHHHHHHHCCEEEEEECCCCCCCCCCCC
NEKLKAVFAPALFDEGIRMKHDPHLIQLVKEPRLRMHPNEAKKRGIMQGDTVRLTTNKGS
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEECCCC
LQAKIKWDGNVAEQTVIIPLGFDLISAHDLDSNLINGLPIDIQLIESQKEESL
EEEEEEECCCCCCEEEEEEECCHHHCCCCCCCHHHCCCCEEEEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]