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The map label for this gene is nuoB

Identifier: 46446194

GI number: 46446194

Start: 694131

End: 694625

Strand: Direct

Name: nuoB

Synonym: pc0560

Alternate gene names: 46446194

Gene position: 694131-694625 (Clockwise)

Preceding gene: 46446193

Following gene: 46446195

Centisome position: 28.75

GC content: 42.22

Gene sequence:

>495_bases
ATGGGAATGAATCATCAACAGGAAAAAACACCGTTTCTCATTGCCCCACTAGAAAAACTAGTCAATTGGGCACGCAGTAA
TTCTCTTTGGCCAGCTCAATTTGGGCTTGCTTGCTGTGCGATTGAAATGATGTCGACTGCAGCAAGTCGTTATGATCTGG
CTCGTTTCGGTATGGAGGTCTTTAGAGCGTCTCCTCGACAAAGCGATGTTATGATTGTCGCAGGGCGAGTTAGTCAAAAA
ATGGCACCCGTTCTTCAAACAATCTATGAACAAATGCTAGAACCTAAATGGGTTATTGCTATGGGAGATTGTGCTTCCTG
CGGAGGAGTTTATAATAACTATGCTATCATTCAGGGTGTCGATAAACTTGTACCCGTCGATGTTTATTTAGCAGGCTGCC
CTCCTCGTCCAGAGGCATTAATAGATGCGTTAATCATGCTGCAAAATAAAATTAAATATGGAGACTCTTCTAAAAAAGGG
AAAAGACATCTATGA

Upstream 100 bases:

>100_bases
TGGGTAAACAAATAGGATCTTTTGCTTTTTATGAAATGACATTTTTCCTGCTGACACTTGTTGTAGGATTTATTTATGTA
TGGCGTAAACGAGGTTTGGA

Downstream 100 bases:

>100_bases
CGTCTCAAATTGTTTTAGATCACATAAAAAAAAACTTTCAAGCATTCATTTTGAATCAAACTCTAGAATTTGGTGAAACG
ACTTTTGAAGTTAATCGAGG

Product: NADH-ubiquinone oxidoreductase chain B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B; NDH-1 subunit B

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MGMNHQQEKTPFLIAPLEKLVNWARSNSLWPAQFGLACCAIEMMSTAASRYDLARFGMEVFRASPRQSDVMIVAGRVSQK
MAPVLQTIYEQMLEPKWVIAMGDCASCGGVYNNYAIIQGVDKLVPVDVYLAGCPPRPEALIDALIMLQNKIKYGDSSKKG
KRHL

Sequences:

>Translated_164_residues
MGMNHQQEKTPFLIAPLEKLVNWARSNSLWPAQFGLACCAIEMMSTAASRYDLARFGMEVFRASPRQSDVMIVAGRVSQK
MAPVLQTIYEQMLEPKWVIAMGDCASCGGVYNNYAIIQGVDKLVPVDVYLAGCPPRPEALIDALIMLQNKIKYGDSSKKG
KRHL
>Mature_163_residues
GMNHQQEKTPFLIAPLEKLVNWARSNSLWPAQFGLACCAIEMMSTAASRYDLARFGMEVFRASPRQSDVMIVAGRVSQKM
APVLQTIYEQMLEPKWVIAMGDCASCGGVYNNYAIIQGVDKLVPVDVYLAGCPPRPEALIDALIMLQNKIKYGDSSKKGK
RHL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family

Homologues:

Organism=Homo sapiens, GI187281616, Length=142, Percent_Identity=59.1549295774648, Blast_Score=187, Evalue=4e-48,
Organism=Escherichia coli, GI1788624, Length=147, Percent_Identity=55.7823129251701, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1789074, Length=123, Percent_Identity=38.2113821138211, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788834, Length=127, Percent_Identity=36.2204724409449, Blast_Score=80, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17509685, Length=147, Percent_Identity=53.0612244897959, Blast_Score=169, Evalue=4e-43,
Organism=Drosophila melanogaster, GI18859983, Length=150, Percent_Identity=52.6666666666667, Blast_Score=178, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24642371, Length=150, Percent_Identity=52.6666666666667, Blast_Score=178, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24651058, Length=150, Percent_Identity=54, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NUOB_PARUW (Q6MDR5)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007559.1
- HSSP:   Q56218
- ProteinModelPortal:   Q6MDR5
- SMR:   Q6MDR5
- STRING:   Q6MDR5
- GeneID:   2780694
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0560
- NMPDR:   fig|264201.1.peg.560
- eggNOG:   COG0377
- HOGENOM:   HBG553221
- OMA:   CCAIEFM
- PhylomeDB:   Q6MDR5
- BioCyc:   CPRO264201:PC0560-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01356
- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406
- PANTHER:   PTHR11995:SF2
- PANTHER:   PTHR11995
- TIGRFAMs:   TIGR01957

Pfam domain/function: PF01058 Oxidored_q6

EC number: =1.6.99.5

Molecular weight: Translated: 18212; Mature: 18080

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS01150 COMPLEX1_20K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMNHQQEKTPFLIAPLEKLVNWARSNSLWPAQFGLACCAIEMMSTAASRYDLARFGMEV
CCCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRASPRQSDVMIVAGRVSQKMAPVLQTIYEQMLEPKWVIAMGDCASCGGVYNNYAIIQGV
HHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHHHHH
DKLVPVDVYLAGCPPRPEALIDALIMLQNKIKYGDSSKKGKRHL
HHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GMNHQQEKTPFLIAPLEKLVNWARSNSLWPAQFGLACCAIEMMSTAASRYDLARFGMEV
CCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRASPRQSDVMIVAGRVSQKMAPVLQTIYEQMLEPKWVIAMGDCASCGGVYNNYAIIQGV
HHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHHHHH
DKLVPVDVYLAGCPPRPEALIDALIMLQNKIKYGDSSKKGKRHL
HHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA