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The map label for this gene is insF1 [C]

Identifier: 45659195

GI number: 45659195

Start: 4140791

End: 4141627

Strand: Reverse

Name: insF1 [C]

Synonym: LIC13377

Alternate gene names: 45659195

Gene position: 4141627-4140791 (Counterclockwise)

Preceding gene: 45659206

Following gene: 45659192

Centisome position: 96.83

GC content: 39.07

Gene sequence:

>837_bases
ATGAAATCGAATTGCTTAGAGCATAGTATAGGGAGCATGGCAAGAGTTTTAGGAGTATCTCGATCAGGATATTATAAATA
TCTAAACCGTCATAAAGATCGGTCAGTTGCTCCTGAACTTACGAACTTTCTCCAAGAGAAGTGGCTTAAGAGTCGTAAGA
ATTACGGTTTTAAACGTCTCTTTCAGGAAGTGAAAAAGTCGAATCTTCCCTATGGAGCGAGGAAAGTTCGAAAAGCGATG
AAACACTGTAAAATTAGCGGGAAACAGAGGAAGCAGTTTAGACCTTTGACAACGAATTCAAAACACGGAGGTAGAATTGC
TCCTGATTTAGTTCAAAGGAAATTTCATCCGAACGAGCAGAACCGAATTTGGGTGTCTGATGTTACATTCATTCGGACTT
CGTTTGGTTGGAGTTATCTCTGTGTGATCCTGGATTTGTATTCACGCAAGACAGTGGGTTGGTCGCTTTCCAATCGTAAT
GATTCTCAGCTGGTATGTGATACGGTATTAAAAGCAGTGTTGTCAAGAAACCCTCGGAAAGGATTGATCTTTCATTCGGA
TCGGGGTTCTAATTTCTGTTCTAAAGAAACACGCAGACTACTAATTGCCAACGGTATCAGACGAAGCAACAGCAGAAAAG
GAAATTGTTGGGACAATGCGGTGGCAGAGTCTTTCTTTAGTTCTCTAAAAAGAGAAATCGAATACAATACATTCTATAAC
ATTGAAGAAGCGGAACATCTTCTATTCGATTTTATCGAAGTGTATTACAATAGATTCAGGTTTCATTCTACATTAGGTTA
TATCAGCCCTGAAGAATTTGAGACAAATATTGCTTAA

Upstream 100 bases:

>100_bases
AAAGACTTCGTAAAGAGAATCTGAGATTAAAGGATGAGAACGCGATCTTAAAAAAGTTTGCGGCCATGCTTTCCCGCGAA
CAGAATCCCGATTGAAGTTC

Downstream 100 bases:

>100_bases
ATGGCTGTCCACTTTTATGTGACTACTTCATTATGGAATTTTTCAACAACTCTAATGAAGATTTATTTTTATTAAGAACT
TGTCCCAAAACCGTCCAATG

Product: transposase, IS1501

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKSNCLEHSIGSMARVLGVSRSGYYKYLNRHKDRSVAPELTNFLQEKWLKSRKNYGFKRLFQEVKKSNLPYGARKVRKAM
KHCKISGKQRKQFRPLTTNSKHGGRIAPDLVQRKFHPNEQNRIWVSDVTFIRTSFGWSYLCVILDLYSRKTVGWSLSNRN
DSQLVCDTVLKAVLSRNPRKGLIFHSDRGSNFCSKETRRLLIANGIRRSNSRKGNCWDNAVAESFFSSLKREIEYNTFYN
IEEAEHLLFDFIEVYYNRFRFHSTLGYISPEEFETNIA

Sequences:

>Translated_278_residues
MKSNCLEHSIGSMARVLGVSRSGYYKYLNRHKDRSVAPELTNFLQEKWLKSRKNYGFKRLFQEVKKSNLPYGARKVRKAM
KHCKISGKQRKQFRPLTTNSKHGGRIAPDLVQRKFHPNEQNRIWVSDVTFIRTSFGWSYLCVILDLYSRKTVGWSLSNRN
DSQLVCDTVLKAVLSRNPRKGLIFHSDRGSNFCSKETRRLLIANGIRRSNSRKGNCWDNAVAESFFSSLKREIEYNTFYN
IEEAEHLLFDFIEVYYNRFRFHSTLGYISPEEFETNIA
>Mature_278_residues
MKSNCLEHSIGSMARVLGVSRSGYYKYLNRHKDRSVAPELTNFLQEKWLKSRKNYGFKRLFQEVKKSNLPYGARKVRKAM
KHCKISGKQRKQFRPLTTNSKHGGRIAPDLVQRKFHPNEQNRIWVSDVTFIRTSFGWSYLCVILDLYSRKTVGWSLSNRN
DSQLVCDTVLKAVLSRNPRKGLIFHSDRGSNFCSKETRRLLIANGIRRSNSRKGNCWDNAVAESFFSSLKREIEYNTFYN
IEEAEHLLFDFIEVYYNRFRFHSTLGYISPEEFETNIA

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=252, Percent_Identity=30.952380952381, Blast_Score=118, Evalue=5e-27,
Organism=Escherichia coli, GI1788405, Length=273, Percent_Identity=35.8974358974359, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1787263, Length=273, Percent_Identity=35.8974358974359, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1786753, Length=273, Percent_Identity=35.8974358974359, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1786570, Length=273, Percent_Identity=35.8974358974359, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1786490, Length=273, Percent_Identity=35.8974358974359, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1789981, Length=268, Percent_Identity=28.3582089552239, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32620; Mature: 32620

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]