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The map label for this gene is eriL

Identifier: 45659181

GI number: 45659181

Start: 4123169

End: 4125016

Strand: Reverse

Name: eriL

Synonym: LIC13362

Alternate gene names: 45659181

Gene position: 4125016-4123169 (Counterclockwise)

Preceding gene: 45659182

Following gene: 45659180

Centisome position: 96.44

GC content: 38.58

Gene sequence:

>1848_bases
ATGAACGAAATAAAACGACCCATTTTTCAAATCAGTGGAAGAAGATCTTTATACTTTTACTGTATCATTACAGGGATTGT
TTCTGGATTAGGGGCGTTTCTTTTTTCCAGAATTCTAGCTGCATGTGAATATTTATTTTTAGATAGGGCGGCTGGTCTTT
CCCTTCCACACGCTTCGGGAGAATTTCTAATCGATTCAAACGATGTATCTTATTGGGAAATCCCTTTTTCGGATGATTAT
AGACCTTGGCTTTTATTTTTTCTTCCGATCATTGGAGGTTTACTTACGGGTTGGATCGTAAATCGTTTTTCACCCGAGTC
TGGAGGAACCGGTTCGGATGCAATGATTGATTCCTTTCACAATCTAGAAGGGAAAATGAATCCAGTCGTTTCGTTGATCA
AATCGATTGCTACCGTCTTTACTCTTGCAAGTGGGGGAAGTGGAGGAAAGGAAGGTCCGATTTCTCAGATCGGAGCAGGT
TTTGGGTCTTTACTTGCAACTCTCTTAAAAGCGGGGGCAAGAGCGAGACGAACTCTTTTACTCGCCGGAACCGCAGGAGG
TTTGGGTGCAATTTTTCACGCTCCATTAGGTGGAGCGTTGACTTCGGTGGAAATGATTTATAGGGAAGATATAGAAAGTG
ATTCTTTGATTCCTTGTATCATCTCTTCGGTTTCGGCTTACTTAGTATATTCTGCTTTGAATGGGTTTAATACTGTATAT
CGAGTTACGAACACTGAATTTTCAAGATATACGGATCTAATTTTTTATTTAGGTTTAGGGGTTCTCTGTTTTTTATGTGG
AGACGTTTTTATCCGAATTTTTAGGAGAGTTCAGTATTTTTCTGCACGTTTGAAAGTTTCTCCGATCATTAAACCTGCGT
TAGGTGGTATTGTTGTAGGGACGATTGGACTTTTTTTACCGGAGACGATCGGAAGCGGAGCGGGGGTGCTTCAAGTCGTT
TTAGATGGTAAAGATCCGGTCGGAAACCAAGGAATTTTTTCATCTATGTTTGAAAGTAAGGGTCTTTGGTTGGTTACGTT
ATTTTTTATTTTGGCCGGAATGAAAATTCTTACTACATCGTTTACTATCGGCACCGGAGGTTCTGCTGGAATGTTTGGGC
CCTCATTGTTCATAGGTGGGATGTTAGGTGGAGGTGTGGGAACTCTTGCCAAAATATTCGTTTATCCAGATCTTTCAGTT
ACGTCGTTTATTTTGGTCGGTATGGGAGCTTTTTATGCGGGTGTGGCAAGTGCTCCGATTGCGGGAATGATTATGATATG
CGAAATGATAGGAAGTTATGTGTTACTTCCTCCTTTGATGGTGGTTTCCATTTTAACGTTTGTATTGAGTCATAAATTAA
GTTTATATCGCGCGCAAAAAGAAAATAGATTTCAATCTCCTGCACATTTTTGGGATATGAATCGGGACTTTTTAGAAGAG
ATTCAGGTTAAAACTTGGAAGAGTAGATTACGCGCAATTGCGGTGACTTACGATCATATTTTACTTTCTAAAATAGAAGA
AGAGGCACTGAAGATTCAAGCGAGTGATTACGTGGTTATAGATCGAAACAACCGATATTTAGGAATTTTATCACTTCGAA
AAGTAAGACACACTTTAGAATCGAGAGATGTTATTGCTAATTTAATTACAGTAGGAGACGTTACGGATATATCTGTACCT
TTTGGAAAACCGGAAGATACATTGGCTGCTATTTTAAAGATTTTAATCGATCGCGATATGGATAAAATTGCAATCGTGGA
AGGGAATCAGTTTATCGGTTATTTTCGTTTTGCAGATCTCATGAAAATATATTTTGAAAATATATTTCCTAAAAATATAA
AATCATAA

Upstream 100 bases:

>100_bases
CGTTTTGAAATACAGTAAAATTTTAAAAAATACTTTAGAAATTTAGAATGTTCTTTTTTATATTGGAACCGCTTTTTTGA
TTTTATAGGGACATCTGCCG

Downstream 100 bases:

>100_bases
AATTCTTTTTCGAAGGATACTGCTTAGCTTTTTAAATTCATACGAAAATGAAATGGTAAAAGGCATATTTAAAAATATTA
AATCCAATCAATAAGACTAG

Product: chloride channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MNEIKRPIFQISGRRSLYFYCIITGIVSGLGAFLFSRILAACEYLFLDRAAGLSLPHASGEFLIDSNDVSYWEIPFSDDY
RPWLLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFHNLEGKMNPVVSLIKSIATVFTLASGGSGGKEGPISQIGAG
FGSLLATLLKAGARARRTLLLAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSALNGFNTVY
RVTNTEFSRYTDLIFYLGLGVLCFLCGDVFIRIFRRVQYFSARLKVSPIIKPALGGIVVGTIGLFLPETIGSGAGVLQVV
LDGKDPVGNQGIFSSMFESKGLWLVTLFFILAGMKILTTSFTIGTGGSAGMFGPSLFIGGMLGGGVGTLAKIFVYPDLSV
TSFILVGMGAFYAGVASAPIAGMIMICEMIGSYVLLPPLMVVSILTFVLSHKLSLYRAQKENRFQSPAHFWDMNRDFLEE
IQVKTWKSRLRAIAVTYDHILLSKIEEEALKIQASDYVVIDRNNRYLGILSLRKVRHTLESRDVIANLITVGDVTDISVP
FGKPEDTLAAILKILIDRDMDKIAIVEGNQFIGYFRFADLMKIYFENIFPKNIKS

Sequences:

>Translated_615_residues
MNEIKRPIFQISGRRSLYFYCIITGIVSGLGAFLFSRILAACEYLFLDRAAGLSLPHASGEFLIDSNDVSYWEIPFSDDY
RPWLLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFHNLEGKMNPVVSLIKSIATVFTLASGGSGGKEGPISQIGAG
FGSLLATLLKAGARARRTLLLAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSALNGFNTVY
RVTNTEFSRYTDLIFYLGLGVLCFLCGDVFIRIFRRVQYFSARLKVSPIIKPALGGIVVGTIGLFLPETIGSGAGVLQVV
LDGKDPVGNQGIFSSMFESKGLWLVTLFFILAGMKILTTSFTIGTGGSAGMFGPSLFIGGMLGGGVGTLAKIFVYPDLSV
TSFILVGMGAFYAGVASAPIAGMIMICEMIGSYVLLPPLMVVSILTFVLSHKLSLYRAQKENRFQSPAHFWDMNRDFLEE
IQVKTWKSRLRAIAVTYDHILLSKIEEEALKIQASDYVVIDRNNRYLGILSLRKVRHTLESRDVIANLITVGDVTDISVP
FGKPEDTLAAILKILIDRDMDKIAIVEGNQFIGYFRFADLMKIYFENIFPKNIKS
>Mature_615_residues
MNEIKRPIFQISGRRSLYFYCIITGIVSGLGAFLFSRILAACEYLFLDRAAGLSLPHASGEFLIDSNDVSYWEIPFSDDY
RPWLLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFHNLEGKMNPVVSLIKSIATVFTLASGGSGGKEGPISQIGAG
FGSLLATLLKAGARARRTLLLAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSALNGFNTVY
RVTNTEFSRYTDLIFYLGLGVLCFLCGDVFIRIFRRVQYFSARLKVSPIIKPALGGIVVGTIGLFLPETIGSGAGVLQVV
LDGKDPVGNQGIFSSMFESKGLWLVTLFFILAGMKILTTSFTIGTGGSAGMFGPSLFIGGMLGGGVGTLAKIFVYPDLSV
TSFILVGMGAFYAGVASAPIAGMIMICEMIGSYVLLPPLMVVSILTFVLSHKLSLYRAQKENRFQSPAHFWDMNRDFLEE
IQVKTWKSRLRAIAVTYDHILLSKIEEEALKIQASDYVVIDRNNRYLGILSLRKVRHTLESRDVIANLITVGDVTDISVP
FGKPEDTLAAILKILIDRDMDKIAIVEGNQFIGYFRFADLMKIYFENIFPKNIKS

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081943, Length=455, Percent_Identity=27.2527472527473, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1786350, Length=386, Percent_Identity=27.2020725388601, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17532615, Length=411, Percent_Identity=24.0875912408759, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 67054; Mature: 67054

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEIKRPIFQISGRRSLYFYCIITGIVSGLGAFLFSRILAACEYLFLDRAAGLSLPHASG
CCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EFLIDSNDVSYWEIPFSDDYRPWLLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFH
CEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
NLEGKMNPVVSLIKSIATVFTLASGGSGGKEGPISQIGAGFGSLLATLLKAGARARRTLL
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCHHHEEEE
LAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSALNGFNTVY
EEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
RVTNTEFSRYTDLIFYLGLGVLCFLCGDVFIRIFRRVQYFSARLKVSPIIKPALGGIVVG
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHH
TIGLFLPETIGSGAGVLQVVLDGKDPVGNQGIFSSMFESKGLWLVTLFFILAGMKILTTS
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCHHHHHEE
FTIGTGGSAGMFGPSLFIGGMLGGGVGTLAKIFVYPDLSVTSFILVGMGAFYAGVASAPI
EEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCH
AGMIMICEMIGSYVLLPPLMVVSILTFVLSHKLSLYRAQKENRFQSPAHFWDMNRDFLEE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
IQVKTWKSRLRAIAVTYDHILLSKIEEEALKIQASDYVVIDRNNRYLGILSLRKVRHTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCEEEHHHHHHHHHHHH
SRDVIANLITVGDVTDISVPFGKPEDTLAAILKILIDRDMDKIAIVEGNQFIGYFRFADL
HHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEHHHHHHHH
MKIYFENIFPKNIKS
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MNEIKRPIFQISGRRSLYFYCIITGIVSGLGAFLFSRILAACEYLFLDRAAGLSLPHASG
CCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EFLIDSNDVSYWEIPFSDDYRPWLLFFLPIIGGLLTGWIVNRFSPESGGTGSDAMIDSFH
CEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
NLEGKMNPVVSLIKSIATVFTLASGGSGGKEGPISQIGAGFGSLLATLLKAGARARRTLL
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCHHHEEEE
LAGTAGGLGAIFHAPLGGALTSVEMIYREDIESDSLIPCIISSVSAYLVYSALNGFNTVY
EEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
RVTNTEFSRYTDLIFYLGLGVLCFLCGDVFIRIFRRVQYFSARLKVSPIIKPALGGIVVG
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCHHHHHHHHHHH
TIGLFLPETIGSGAGVLQVVLDGKDPVGNQGIFSSMFESKGLWLVTLFFILAGMKILTTS
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCHHHHHEE
FTIGTGGSAGMFGPSLFIGGMLGGGVGTLAKIFVYPDLSVTSFILVGMGAFYAGVASAPI
EEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCH
AGMIMICEMIGSYVLLPPLMVVSILTFVLSHKLSLYRAQKENRFQSPAHFWDMNRDFLEE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
IQVKTWKSRLRAIAVTYDHILLSKIEEEALKIQASDYVVIDRNNRYLGILSLRKVRHTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCEEEHHHHHHHHHHHH
SRDVIANLITVGDVTDISVPFGKPEDTLAAILKILIDRDMDKIAIVEGNQFIGYFRFADL
HHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEHHHHHHHH
MKIYFENIFPKNIKS
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]