| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is recD
Identifier: 45658521
GI number: 45658521
Start: 3255040
End: 3256893
Strand: Reverse
Name: recD
Synonym: LIC12685
Alternate gene names: 45658521
Gene position: 3256893-3255040 (Counterclockwise)
Preceding gene: 45658522
Following gene: 45658520
Centisome position: 76.15
GC content: 33.33
Gene sequence:
>1854_bases ATGGGAGAAATCGAATTGATTTTTATTGAAAAACTAAGGACGGATATTTTAGAACTGATTCAGTCATCGGAATTCGAAAA GAAAAAATTAATAAAAGTATCAGAAGAGGACTCTAATTATATATTAGAAATATTGAATTCAATTTGGGAGGCTACTCAGG AAGGAAGTTTATGTGTTCCTGTAAAACAAGAATGGAAGAAAATTTTAAAAATAAAGCTCCCCGGTCTTGTCGTAGATCGG TTTGAAAATACGGAATGGGTGTATTTTGAAAAAACGTATCGTTCTAAAATTGAATTGGAACGTCTTTTAAAAGAAAGAAT CGAAAATGATGTTTCGGTTAATGTGGATACGGATCGAGTTGAAAAAATTCTAAAGGATCTGGAATCGAAAAGTTTTTCAC TGAAAAAAAATCAAAAAAAAACAATCTTTTCTTGTTTAAACTCCTCTTTCCAAATTATAAGTGGAGGACCTGGTACTGGA AAAACAACCATAGTAGCGTTTTTATTACAAATTTTGAATGAACTAAAGCAACTTCCTTCTCCAGAAAAAATTGCACTTGT TGCACCGACTGGAAGGGCGGCTCAGAGGTTAACGGAATCGGTTCAAGAAAATTTAAAAAAAATCTCCACGTCTCTCGAAA ATGGATTTCTAAGAGGACAAACGATTCACGGACTTTTAAACTACAAACAGTCGTTAGGTGGGTTTTATTATAATCGAGAA AGATACCTTCCACATAGACTAATTATCGTGGACGAAGTTTCTATGGTAGATTTAGATCTGATGCTTTCTCTTTGGAATTC AATTCCTAAAAATGAGACGATTCAAGAAGGAACCATTCCGTTTCGGTTTATATTGATTGGAGATCCACATCAACTTCCTT CTGTAGAAAAAGGTGCCGTGTTAAGCGATTTTTTATCCGTGTTAGAATCTAAACGATTTCATTTTGTTTCTAAATTAGAA GAAAGTAATCGTCAGCAACCAAATACAAACGGAGAAGTTTCAAAGATAGTCACACTCGCAGAAGAAATTTTAAAATATTC TCCTGAAAATCTAAACTTAGGAACTAAGATAGATGAAAGTTTTCCAAAAACGAATCAAATTAAAGAGAATATTTTATACA AAAGTGAAGTTGTATGGTTGCAAAATATTGAAAGTAGCACTTCCGATTATTTTTCTAGAGATGAGTTAGTTGAAAAACTT TGGAAAGAAATTTTTTATCCTCAAATTGATAGAATCTCTTCTTGGAAAATTCAGGATTCTTTTTGTTTTGATAAACCAGA TTTTATTCAAAAATTTCAAGAGGAACTAAAACGATTTCGTTGTCTTACGATTTTTAGGAGTGGCTATTGGGGAGTGGATG CGATTCAAACAAAGATCATGAATTTGGCTGCTCAAAATCTTTTTTTTGGAAAGGGCGGGAACTTTTTTGCCAAACGACTT TCCAAGGGAATTTATTTTGTAGGTCTTCCCATTTTAATTACTCGAAACGATAAAAGTAGAAAACTTTTTAACGGAGATAT TGGAATCGTATTAAAAACGGAATCTACCGGAGAACTTAGGGCGGTGTTTCCGATTGAAGGAAAACTTTTTCAGTTTGCGT TAGACACTCTTCCAGAGCATGAACCTGCGTTTGTAATGAGTGTACATAAAAGTCAGGGATCAGAATATGATACAATCCTA ATTTATCTTCCAGATTCTATAGAAGAGGAAAAATCTAATGGGTTACTCAATCGTCAAGTTCTTTATACAGCAATTACAAG AGCTAAAAAACAAGTGATCTTGGCTGGAAATCCGCAAACCTGGGAAATTGGAATCGCCAATTTTCAAAATAGAAATACTG GGTTTAGAATTTAA
Upstream 100 bases:
>100_bases TGATCTATGGAGAAAGTTCTGGAATTTATTCAGATTTTTTTTGGAGTTTGGAAAGAATCGAATCTATCCGTAAAACTGTT TTAGAATCCACGACTTTTCG
Downstream 100 bases:
>100_bases ATTAAAATGAATTGAGTGTAATGCCAATAGAAGCAAGACGTTAATTACTAGGTTTGAGCTTTTTGGTAAAGTACAATTAG GTTTTTTGAGATGGGTTGTG
Product: exodeoxyribonuclease v subunit alpha
Products: NA
Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]
Number of amino acids: Translated: 617; Mature: 616
Protein sequence:
>617_residues MGEIELIFIEKLRTDILELIQSSEFEKKKLIKVSEEDSNYILEILNSIWEATQEGSLCVPVKQEWKKILKIKLPGLVVDR FENTEWVYFEKTYRSKIELERLLKERIENDVSVNVDTDRVEKILKDLESKSFSLKKNQKKTIFSCLNSSFQIISGGPGTG KTTIVAFLLQILNELKQLPSPEKIALVAPTGRAAQRLTESVQENLKKISTSLENGFLRGQTIHGLLNYKQSLGGFYYNRE RYLPHRLIIVDEVSMVDLDLMLSLWNSIPKNETIQEGTIPFRFILIGDPHQLPSVEKGAVLSDFLSVLESKRFHFVSKLE ESNRQQPNTNGEVSKIVTLAEEILKYSPENLNLGTKIDESFPKTNQIKENILYKSEVVWLQNIESSTSDYFSRDELVEKL WKEIFYPQIDRISSWKIQDSFCFDKPDFIQKFQEELKRFRCLTIFRSGYWGVDAIQTKIMNLAAQNLFFGKGGNFFAKRL SKGIYFVGLPILITRNDKSRKLFNGDIGIVLKTESTGELRAVFPIEGKLFQFALDTLPEHEPAFVMSVHKSQGSEYDTIL IYLPDSIEEEKSNGLLNRQVLYTAITRAKKQVILAGNPQTWEIGIANFQNRNTGFRI
Sequences:
>Translated_617_residues MGEIELIFIEKLRTDILELIQSSEFEKKKLIKVSEEDSNYILEILNSIWEATQEGSLCVPVKQEWKKILKIKLPGLVVDR FENTEWVYFEKTYRSKIELERLLKERIENDVSVNVDTDRVEKILKDLESKSFSLKKNQKKTIFSCLNSSFQIISGGPGTG KTTIVAFLLQILNELKQLPSPEKIALVAPTGRAAQRLTESVQENLKKISTSLENGFLRGQTIHGLLNYKQSLGGFYYNRE RYLPHRLIIVDEVSMVDLDLMLSLWNSIPKNETIQEGTIPFRFILIGDPHQLPSVEKGAVLSDFLSVLESKRFHFVSKLE ESNRQQPNTNGEVSKIVTLAEEILKYSPENLNLGTKIDESFPKTNQIKENILYKSEVVWLQNIESSTSDYFSRDELVEKL WKEIFYPQIDRISSWKIQDSFCFDKPDFIQKFQEELKRFRCLTIFRSGYWGVDAIQTKIMNLAAQNLFFGKGGNFFAKRL SKGIYFVGLPILITRNDKSRKLFNGDIGIVLKTESTGELRAVFPIEGKLFQFALDTLPEHEPAFVMSVHKSQGSEYDTIL IYLPDSIEEEKSNGLLNRQVLYTAITRAKKQVILAGNPQTWEIGIANFQNRNTGFRI >Mature_616_residues GEIELIFIEKLRTDILELIQSSEFEKKKLIKVSEEDSNYILEILNSIWEATQEGSLCVPVKQEWKKILKIKLPGLVVDRF ENTEWVYFEKTYRSKIELERLLKERIENDVSVNVDTDRVEKILKDLESKSFSLKKNQKKTIFSCLNSSFQIISGGPGTGK TTIVAFLLQILNELKQLPSPEKIALVAPTGRAAQRLTESVQENLKKISTSLENGFLRGQTIHGLLNYKQSLGGFYYNRER YLPHRLIIVDEVSMVDLDLMLSLWNSIPKNETIQEGTIPFRFILIGDPHQLPSVEKGAVLSDFLSVLESKRFHFVSKLEE SNRQQPNTNGEVSKIVTLAEEILKYSPENLNLGTKIDESFPKTNQIKENILYKSEVVWLQNIESSTSDYFSRDELVEKLW KEIFYPQIDRISSWKIQDSFCFDKPDFIQKFQEELKRFRCLTIFRSGYWGVDAIQTKIMNLAAQNLFFGKGGNFFAKRLS KGIYFVGLPILITRNDKSRKLFNGDIGIVLKTESTGELRAVFPIEGKLFQFALDTLPEHEPAFVMSVHKSQGSEYDTILI YLPDSIEEEKSNGLLNRQVLYTAITRAKKQVILAGNPQTWEIGIANFQNRNTGFRI
Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi
COG id: COG0507
COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the recD family [H]
Homologues:
Organism=Escherichia coli, GI1789182, Length=525, Percent_Identity=27.8095238095238, Blast_Score=138, Evalue=1e-33,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR007807 - InterPro: IPR006344 - InterPro: IPR000606 [H]
Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]
EC number: =3.1.11.5 [H]
Molecular weight: Translated: 70979; Mature: 70847
Theoretical pI: Translated: 7.53; Mature: 7.53
Prosite motif: PS00678 WD_REPEATS_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 0.6 %Met (Mature Protein) 1.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGEIELIFIEKLRTDILELIQSSEFEKKKLIKVSEEDSNYILEILNSIWEATQEGSLCVP CCCEEEEEHHHHHHHHHHHHHCCCCCHHHCEEECCCCCHHHHHHHHHHHHHCCCCCEEEC VKQEWKKILKIKLPGLVVDRFENTEWVYFEKTYRSKIELERLLKERIENDVSVNVDTDRV CHHHHHHHHHHCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEECCHHHH EKILKDLESKSFSLKKNQKKTIFSCLNSSFQIISGGPGTGKTTIVAFLLQILNELKQLPS HHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCC PEKIALVAPTGRAAQRLTESVQENLKKISTSLENGFLRGQTIHGLLNYKQSLGGFYYNRE CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCC RYLPHRLIIVDEVSMVDLDLMLSLWNSIPKNETIQEGTIPFRFILIGDPHQLPSVEKGAV CCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHH LSDFLSVLESKRFHFVSKLEESNRQQPNTNGEVSKIVTLAEEILKYSPENLNLGTKIDES HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC FPKTNQIKENILYKSEVVWLQNIESSTSDYFSRDELVEKLWKEIFYPQIDRISSWKIQDS CCCHHHHHHHHHHHHHHHEECCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEECCC FCFDKPDFIQKFQEELKRFRCLTIFRSGYWGVDAIQTKIMNLAAQNLFFGKGGNFFAKRL CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHH SKGIYFVGLPILITRNDKSRKLFNGDIGIVLKTESTGELRAVFPIEGKLFQFALDTLPEH HCCEEEEEEEEEEECCCCCCEEECCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCC EPAFVMSVHKSQGSEYDTILIYLPDSIEEEKSNGLLNRQVLYTAITRAKKQVILAGNPQT CCCEEEEEECCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCE WEIGIANFQNRNTGFRI EEEECCCCCCCCCCCCC >Mature Secondary Structure GEIELIFIEKLRTDILELIQSSEFEKKKLIKVSEEDSNYILEILNSIWEATQEGSLCVP CCEEEEEHHHHHHHHHHHHHCCCCCHHHCEEECCCCCHHHHHHHHHHHHHCCCCCEEEC VKQEWKKILKIKLPGLVVDRFENTEWVYFEKTYRSKIELERLLKERIENDVSVNVDTDRV CHHHHHHHHHHCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEECCHHHH EKILKDLESKSFSLKKNQKKTIFSCLNSSFQIISGGPGTGKTTIVAFLLQILNELKQLPS HHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCC PEKIALVAPTGRAAQRLTESVQENLKKISTSLENGFLRGQTIHGLLNYKQSLGGFYYNRE CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCC RYLPHRLIIVDEVSMVDLDLMLSLWNSIPKNETIQEGTIPFRFILIGDPHQLPSVEKGAV CCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHH LSDFLSVLESKRFHFVSKLEESNRQQPNTNGEVSKIVTLAEEILKYSPENLNLGTKIDES HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC FPKTNQIKENILYKSEVVWLQNIESSTSDYFSRDELVEKLWKEIFYPQIDRISSWKIQDS CCCHHHHHHHHHHHHHHHEECCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEECCC FCFDKPDFIQKFQEELKRFRCLTIFRSGYWGVDAIQTKIMNLAAQNLFFGKGGNFFAKRL CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHH SKGIYFVGLPILITRNDKSRKLFNGDIGIVLKTESTGELRAVFPIEGKLFQFALDTLPEH HCCEEEEEEEEEEECCCCCCEEECCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCC EPAFVMSVHKSQGSEYDTILIYLPDSIEEEKSNGLLNRQVLYTAITRAKKQVILAGNPQT CCCEEEEEECCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCE WEIGIANFQNRNTGFRI EEEECCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]