Definition Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence.
Accession NC_005823
Length 4,277,185

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The map label for this gene is ykuI [H]

Identifier: 45657781

GI number: 45657781

Start: 2320123

End: 2321397

Strand: Reverse

Name: ykuI [H]

Synonym: LIC11921

Alternate gene names: 45657781

Gene position: 2321397-2320123 (Counterclockwise)

Preceding gene: 45657785

Following gene: 45657779

Centisome position: 54.27

GC content: 34.59

Gene sequence:

>1275_bases
ATGATCGGCATTTCTCCAAAAACGAAATTGGAATGGGATCTTTGGTTCCAATCCGGAGAAATTGTTCCTTTTTTTCAACC
CATCCTTTCTGTAGAAAGGGATTCTATTTTCGGTTATGAAACTCTGGGAAGGTTTCGAGATCAATCCGGAAAAATCCATT
CTTTAGGTCCTTTCTTTTTGAATGCGTTGTCCGGGGTAGAAGATCTTCAAGAAAGAAGAGAGATCTACATTCTTAAAAGA
GATATTGATCGTAGTATTCGTAAAAAAGCACTTCTCCATCTTTTAAAAAATCAGAATCGATTTCCAGAAGCAAAATTATT
CGTAAATATTTCCCCCGCGTATATGAGGGATCATATCGAGGAAGAAGAGGTAGATCCATATACAATTCGACTTGTGAAAG
AATTTGGTTTAGATCCTTCCAAAATAGTTATTGAAATTGTAGAAGAACATTTTGACGGAAGTATAGAAAGTTTAAGACCT
CTCATTTCTCGTTATAAAGAAGAAGGATTTTTAGTAGCGATTGACGATTTGGGTTCTCGTTCTTCTAATTTAGATCGAAT
TGGAATTTTCCATCCGGATATTTTGAAAGTAGATCTTCAGATGCTTAGGCATTCGGTCATTTCTAGAAATTTTCAGGAGA
TTCTTTTTACAATTTCTAGACTTTCTGAATCTCTAGGTTGTTCTCTATTGTTTGAAGGGATTGAAAATGAGACGGAACTT
TTTCAATCTCTTACTTACAGCGCACGTTTTTTACAGGGATTTTATTTTGCAGAAGCCCTTCCGAATATGGTAGGTCAAGA
GGAGTTAAAACTTAGATTTTCTGCTGTTCATGAATGTTTCTTAAACCATAAACGAAATCAGTTAGTAAAAAGAATTCAGT
TGGAAAAAGAATTGGAAGAGAAGCTGGATCTTTCCGGAATTATAGTAAATGCAGAAGAAGAACTTTGTTCGATTCAAATC
CAGAACCCTAACTTACTGAGCAATTTTGTATTTCGAATTTATGCTACCAATCTGATTGGAAGCCAGGTTTCTCCAAACTA
TATGAAAATTGGAAATTCTTCTATAGACATAGATTCTTCTTTTGTAGGAAGAAATTGGAGTTGGAGACCGTATTTTTTGG
AACAACTTTATAAATCAATGAAGGATACTCGAGCGGAATGGATTATTAGTAATCCGTATTACGACATCAGCTACGGAATT
CTTCTCGTGACGTATAGTAAAAAAATTTCTGAGCAAAATGTACTATTTGTAGATGCTCAAGTTCTTGAATATTAG

Upstream 100 bases:

>100_bases
TTCCTTTTTTCATAAGCAATGTCAGGAAGTAATGTTGTTTTTTTATATTTCACGGAATTTCCTTGTAGGATTAAGACATT
CCAAAAACGTGTTAATCTAA

Downstream 100 bases:

>100_bases
AAATATATAATAAACTATTATTCAATATTTTGTTTTGAAATAATGTTTTTTATAAAAATTTGAGAATAGGGATGAGTAAA
ATCTTTAGAATACTATAAAC

Product: putative diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MIGISPKTKLEWDLWFQSGEIVPFFQPILSVERDSIFGYETLGRFRDQSGKIHSLGPFFLNALSGVEDLQERREIYILKR
DIDRSIRKKALLHLLKNQNRFPEAKLFVNISPAYMRDHIEEEEVDPYTIRLVKEFGLDPSKIVIEIVEEHFDGSIESLRP
LISRYKEEGFLVAIDDLGSRSSNLDRIGIFHPDILKVDLQMLRHSVISRNFQEILFTISRLSESLGCSLLFEGIENETEL
FQSLTYSARFLQGFYFAEALPNMVGQEELKLRFSAVHECFLNHKRNQLVKRIQLEKELEEKLDLSGIIVNAEEELCSIQI
QNPNLLSNFVFRIYATNLIGSQVSPNYMKIGNSSIDIDSSFVGRNWSWRPYFLEQLYKSMKDTRAEWIISNPYYDISYGI
LLVTYSKKISEQNVLFVDAQVLEY

Sequences:

>Translated_424_residues
MIGISPKTKLEWDLWFQSGEIVPFFQPILSVERDSIFGYETLGRFRDQSGKIHSLGPFFLNALSGVEDLQERREIYILKR
DIDRSIRKKALLHLLKNQNRFPEAKLFVNISPAYMRDHIEEEEVDPYTIRLVKEFGLDPSKIVIEIVEEHFDGSIESLRP
LISRYKEEGFLVAIDDLGSRSSNLDRIGIFHPDILKVDLQMLRHSVISRNFQEILFTISRLSESLGCSLLFEGIENETEL
FQSLTYSARFLQGFYFAEALPNMVGQEELKLRFSAVHECFLNHKRNQLVKRIQLEKELEEKLDLSGIIVNAEEELCSIQI
QNPNLLSNFVFRIYATNLIGSQVSPNYMKIGNSSIDIDSSFVGRNWSWRPYFLEQLYKSMKDTRAEWIISNPYYDISYGI
LLVTYSKKISEQNVLFVDAQVLEY
>Mature_424_residues
MIGISPKTKLEWDLWFQSGEIVPFFQPILSVERDSIFGYETLGRFRDQSGKIHSLGPFFLNALSGVEDLQERREIYILKR
DIDRSIRKKALLHLLKNQNRFPEAKLFVNISPAYMRDHIEEEEVDPYTIRLVKEFGLDPSKIVIEIVEEHFDGSIESLRP
LISRYKEEGFLVAIDDLGSRSSNLDRIGIFHPDILKVDLQMLRHSVISRNFQEILFTISRLSESLGCSLLFEGIENETEL
FQSLTYSARFLQGFYFAEALPNMVGQEELKLRFSAVHECFLNHKRNQLVKRIQLEKELEEKLDLSGIIVNAEEELCSIQI
QNPNLLSNFVFRIYATNLIGSQVSPNYMKIGNSSIDIDSSFVGRNWSWRPYFLEQLYKSMKDTRAEWIISNPYYDISYGI
LLVTYSKKISEQNVLFVDAQVLEY

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=268, Percent_Identity=26.4925373134328, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081743, Length=248, Percent_Identity=24.1935483870968, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081845, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633
- InterPro:   IPR018842 [H]

Pfam domain/function: PF00563 EAL; PF10388 YkuI_C [H]

EC number: NA

Molecular weight: Translated: 49342; Mature: 49342

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGISPKTKLEWDLWFQSGEIVPFFQPILSVERDSIFGYETLGRFRDQSGKIHSLGPFFL
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCHHHH
NALSGVEDLQERREIYILKRDIDRSIRKKALLHLLKNQNRFPEAKLFVNISPAYMRDHIE
HHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHCCC
EEEVDPYTIRLVKEFGLDPSKIVIEIVEEHFDGSIESLRPLISRYKEEGFLVAIDDLGSR
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCC
SSNLDRIGIFHPDILKVDLQMLRHSVISRNFQEILFTISRLSESLGCSLLFEGIENETEL
CCCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHCCCCHHHH
FQSLTYSARFLQGFYFAEALPNMVGQEELKLRFSAVHECFLNHKRNQLVKRIQLEKELEE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
KLDLSGIIVNAEEELCSIQIQNPNLLSNFVFRIYATNLIGSQVSPNYMKIGNSSIDIDSS
HCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCC
FVGRNWSWRPYFLEQLYKSMKDTRAEWIISNPYYDISYGILLVTYSKKISEQNVLFVDAQ
CCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCEEEECCEEEEEECHHCCCCCEEEEEHH
VLEY
HHCC
>Mature Secondary Structure
MIGISPKTKLEWDLWFQSGEIVPFFQPILSVERDSIFGYETLGRFRDQSGKIHSLGPFFL
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCHHHH
NALSGVEDLQERREIYILKRDIDRSIRKKALLHLLKNQNRFPEAKLFVNISPAYMRDHIE
HHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHCCC
EEEVDPYTIRLVKEFGLDPSKIVIEIVEEHFDGSIESLRPLISRYKEEGFLVAIDDLGSR
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCC
SSNLDRIGIFHPDILKVDLQMLRHSVISRNFQEILFTISRLSESLGCSLLFEGIENETEL
CCCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHCCCCHHHH
FQSLTYSARFLQGFYFAEALPNMVGQEELKLRFSAVHECFLNHKRNQLVKRIQLEKELEE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
KLDLSGIIVNAEEELCSIQIQNPNLLSNFVFRIYATNLIGSQVSPNYMKIGNSSIDIDSS
HCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCC
FVGRNWSWRPYFLEQLYKSMKDTRAEWIISNPYYDISYGILLVTYSKKISEQNVLFVDAQ
CCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCEEEECCEEEEEECHHCCCCCEEEEEHH
VLEY
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]