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The map label for this gene is cysQ [H]

Identifier: 45657498

GI number: 45657498

Start: 1990894

End: 1991739

Strand: Direct

Name: cysQ [H]

Synonym: LIC11626

Alternate gene names: 45657498

Gene position: 1990894-1991739 (Clockwise)

Preceding gene: 45657497

Following gene: 45657499

Centisome position: 46.55

GC content: 37.23

Gene sequence:

>846_bases
TTGAATTCGATTCTATATCTTCAGTCTGCCGTAGATTCTGTACTAGAGGCTGGCAAAATTGTATTAGAAATTTATCATTC
CGATTTTAAGGTCAAGGATAAAGGAAAAAACGATCCAGTAACCGAAGCAGATCTGAAAGCAAGTTCTCATATTTCGGAAA
GTTTACGTTTTTTGAATATTCCAATTCTTTCCGAAGAGGACTCTGAAAAGAAGGATGTTTCCAAATTACAAACAGTTTGG
ATTTTGGATCCAATTGACGGAACCAGGGAATTTATACATAAAAATCCGGAGTTTGCGATCAGTCTCGGTTTGTCTATTCT
TGGAAAAGCGGTTTTAGGAGTGGTTTTTAACCCGGTTACCTTAGAATTGATCTATGGAGCAGAGGATTTAGGAGTAGTTT
ATCAAAAGTTGGAAAATATACCTGATTTTTTTTCAGTTAAACTCCAGAACTTTACAAAAATATTAAGTGATTTTAAACCT
ATTCAGAAAGTTCTTATTTCCAGAACCGAAGAAAAAGAAGGTCTTTTTTCTTCTTCTATGATTCCTTTCGGTTGGGAATT
TGTGGCAATGGGCTCGATCGCGTATAAACTTGGTTTGGTGGCGGCGGGAAAAGCGGCTCTTTCCATTTCTTTAAAACCAA
AAAATGATTGGGACATTTGTGCGGGAATTGCGCTTATAAATTCTTCGGGAGGCTCCGATCTAGAAATTAAAACCGGTGAA
CCCTATAAATTTCAAACTTTAAATGGAAAGGGAGAGGGGCTTATCGCAGGACATACTCGTTCCCTTACCCAGGTTTGGGA
AAATTCTAAATCGTATTTTCAATCCGGTTTACGGGATTGGAATTAA

Upstream 100 bases:

>100_bases
TTATCTTCGTCCCGAAAATTTGGATGATCCTCATAAAGAAAATACTTCGGCGCCAGATGGTAAGAGTGGAAAGTAATTTT
TATTTCGAGTATTTTCTTTT

Downstream 100 bases:

>100_bases
TGTATTTTGTATTAAATTCGACCTGTTTTTGGCATTTGAATTTATTTTCTTAAGTGTCCTTAAGAAATTTGTTAATCCTT
TTTTATCGATTTTATATATG

Product: inositol monophosphatase family protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MNSILYLQSAVDSVLEAGKIVLEIYHSDFKVKDKGKNDPVTEADLKASSHISESLRFLNIPILSEEDSEKKDVSKLQTVW
ILDPIDGTREFIHKNPEFAISLGLSILGKAVLGVVFNPVTLELIYGAEDLGVVYQKLENIPDFFSVKLQNFTKILSDFKP
IQKVLISRTEEKEGLFSSSMIPFGWEFVAMGSIAYKLGLVAAGKAALSISLKPKNDWDICAGIALINSSGGSDLEIKTGE
PYKFQTLNGKGEGLIAGHTRSLTQVWENSKSYFQSGLRDWN

Sequences:

>Translated_281_residues
MNSILYLQSAVDSVLEAGKIVLEIYHSDFKVKDKGKNDPVTEADLKASSHISESLRFLNIPILSEEDSEKKDVSKLQTVW
ILDPIDGTREFIHKNPEFAISLGLSILGKAVLGVVFNPVTLELIYGAEDLGVVYQKLENIPDFFSVKLQNFTKILSDFKP
IQKVLISRTEEKEGLFSSSMIPFGWEFVAMGSIAYKLGLVAAGKAALSISLKPKNDWDICAGIALINSSGGSDLEIKTGE
PYKFQTLNGKGEGLIAGHTRSLTQVWENSKSYFQSGLRDWN
>Mature_281_residues
MNSILYLQSAVDSVLEAGKIVLEIYHSDFKVKDKGKNDPVTEADLKASSHISESLRFLNIPILSEEDSEKKDVSKLQTVW
ILDPIDGTREFIHKNPEFAISLGLSILGKAVLGVVFNPVTLELIYGAEDLGVVYQKLENIPDFFSVKLQNFTKILSDFKP
IQKVLISRTEEKEGLFSSSMIPFGWEFVAMGSIAYKLGLVAAGKAALSISLKPKNDWDICAGIALINSSGGSDLEIKTGE
PYKFQTLNGKGEGLIAGHTRSLTQVWENSKSYFQSGLRDWN

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=207, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788882, Length=280, Percent_Identity=27.5, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=126, Percent_Identity=36.5079365079365, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320493, Length=246, Percent_Identity=30.4878048780488, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24664918, Length=236, Percent_Identity=30.9322033898305, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21357329, Length=252, Percent_Identity=27.3809523809524, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24664926, Length=241, Percent_Identity=28.2157676348548, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 31022; Mature: 31022

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSILYLQSAVDSVLEAGKIVLEIYHSDFKVKDKGKNDPVTEADLKASSHISESLRFLNI
CCCEEHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHEEEC
PILSEEDSEKKDVSKLQTVWILDPIDGTREFIHKNPEFAISLGLSILGKAVLGVVFNPVT
EEECCCCCHHHHHHHHEEEEEECCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCEE
LELIYGAEDLGVVYQKLENIPDFFSVKLQNFTKILSDFKPIQKVLISRTEEKEGLFSSSM
EEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHCCC
IPFGWEFVAMGSIAYKLGLVAAGKAALSISLKPKNDWDICAGIALINSSGGSDLEIKTGE
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHEEEEEEECCCCCEEEEECCC
PYKFQTLNGKGEGLIAGHTRSLTQVWENSKSYFQSGLRDWN
CEEEEEECCCCCEEEECCHHHHHHHHHCHHHHHHHHCCCCC
>Mature Secondary Structure
MNSILYLQSAVDSVLEAGKIVLEIYHSDFKVKDKGKNDPVTEADLKASSHISESLRFLNI
CCCEEHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHEEEC
PILSEEDSEKKDVSKLQTVWILDPIDGTREFIHKNPEFAISLGLSILGKAVLGVVFNPVT
EEECCCCCHHHHHHHHEEEEEECCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCEE
LELIYGAEDLGVVYQKLENIPDFFSVKLQNFTKILSDFKPIQKVLISRTEEKEGLFSSSM
EEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHCCC
IPFGWEFVAMGSIAYKLGLVAAGKAALSISLKPKNDWDICAGIALINSSGGSDLEIKTGE
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHEEEEEEECCCCCEEEEECCC
PYKFQTLNGKGEGLIAGHTRSLTQVWENSKSYFQSGLRDWN
CEEEEEECCCCCEEEECCHHHHHHHHHCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]