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The map label for this gene is rpe

Identifier: 45657427

GI number: 45657427

Start: 1917880

End: 1918527

Strand: Direct

Name: rpe

Synonym: LIC11554

Alternate gene names: 45657427

Gene position: 1917880-1918527 (Clockwise)

Preceding gene: 45657426

Following gene: 161621775

Centisome position: 44.84

GC content: 36.11

Gene sequence:

>648_bases
TTGAAAATTTCTGCATCCATACTTGCAACTAAACTCACAGAACTTGTAAAAACGGTTCCTAATTACGATCCGACTGCGAT
AGATCTTATACACATGGACGTTATGGATGGTAATTTCGTTCCACAAATTAGTTTCGGAGAGGCTCTCACTAAGGAAGTAA
AATCTCTCACGTCGATTCCGTTAGACGTTCATTTAATGGTTGCTAAACCGGAAAACCATGTTTTTAAATATTATGAATTC
AATCCTTATTGTATTACGTTTCATATCGAAACGACTGACTTTCCGATTCGTCTTGCGCAAGAAATCAAAAGCCATGGAAC
AAAAGTAGGAGTTTCTTTAAATCCAGGAACTCCGGTTTCTTCTTTAGAAAATGTTTTACCTTATGTGGATTTAATTTTAT
TAATGACAGTAGAGCCTGGTTTTTACGGACAGAAATTCATAATCAATGGAATGGATAAAATTCGTAAGGTAAAAGAACTG
ATTGGTTCTAGACCGATTGAACTTGAAGTAGACGGAGGGGTCAACGATACCAATATCCAAGAACTAAGAAAAAACGGAGT
GGATATAGTAGTAGTTGGAGCTGGGCTTTATAAAACTGGAAATCCGGTAGAAAATGCAAAAAATCTAAAGTATTTAGCCC
GGGTTTAA

Upstream 100 bases:

>100_bases
AAAAATTTCAAACTGTGTTTTATCGAAAAGGAAGTGTAAAACTTACTCTTTTAGATGCTTCCGATTCCAAGATAAAATCC
AAATCTTATGAGAGTGAACT

Downstream 100 bases:

>100_bases
ATTAAGGAACTCGTTTTTTAGTAAGTTACTACTCAGACGGATGAAAATAATACCCAAAGTCAACGATCGATTTTACAAAG
ATGCAAAGGTTCTCAAAAAT

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKISASILATKLTELVKTVPNYDPTAIDLIHMDVMDGNFVPQISFGEALTKEVKSLTSIPLDVHLMVAKPENHVFKYYEF
NPYCITFHIETTDFPIRLAQEIKSHGTKVGVSLNPGTPVSSLENVLPYVDLILLMTVEPGFYGQKFIINGMDKIRKVKEL
IGSRPIELEVDGGVNDTNIQELRKNGVDIVVVGAGLYKTGNPVENAKNLKYLARV

Sequences:

>Translated_215_residues
MKISASILATKLTELVKTVPNYDPTAIDLIHMDVMDGNFVPQISFGEALTKEVKSLTSIPLDVHLMVAKPENHVFKYYEF
NPYCITFHIETTDFPIRLAQEIKSHGTKVGVSLNPGTPVSSLENVLPYVDLILLMTVEPGFYGQKFIINGMDKIRKVKEL
IGSRPIELEVDGGVNDTNIQELRKNGVDIVVVGAGLYKTGNPVENAKNLKYLARV
>Mature_215_residues
MKISASILATKLTELVKTVPNYDPTAIDLIHMDVMDGNFVPQISFGEALTKEVKSLTSIPLDVHLMVAKPENHVFKYYEF
NPYCITFHIETTDFPIRLAQEIKSHGTKVGVSLNPGTPVSSLENVLPYVDLILLMTVEPGFYGQKFIINGMDKIRKVKEL
IGSRPIELEVDGGVNDTNIQELRKNGVDIVVVGAGLYKTGNPVENAKNLKYLARV

Specific function: D-ALLOSE METABOLISM. ESSENTIAL FOR THIS PATHWAY. [C]

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=203, Percent_Identity=36.4532019704434, Blast_Score=131, Evalue=4e-31,
Organism=Homo sapiens, GI219879828, Length=205, Percent_Identity=36.5853658536585, Blast_Score=127, Evalue=6e-30,
Organism=Homo sapiens, GI24307923, Length=158, Percent_Identity=31.6455696202532, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1790523, Length=213, Percent_Identity=35.6807511737089, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1789788, Length=198, Percent_Identity=37.8787878787879, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790754, Length=172, Percent_Identity=31.3953488372093, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17552948, Length=204, Percent_Identity=36.2745098039216, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322341, Length=213, Percent_Identity=32.3943661971831, Blast_Score=124, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=32.7014218009479, Blast_Score=126, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23844; Mature: 23844

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISASILATKLTELVKTVPNYDPTAIDLIHMDVMDGNFVPQISFGEALTKEVKSLTSIP
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
LDVHLMVAKPENHVFKYYEFNPYCITFHIETTDFPIRLAQEIKSHGTKVGVSLNPGTPVS
EEEEEEEECCCCCEEEEEEECCEEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHH
SLENVLPYVDLILLMTVEPGFYGQKFIINGMDKIRKVKELIGSRPIELEVDGGVNDTNIQ
HHHHHHHHHHHHHHEEECCCCCCCHHEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
ELRKNGVDIVVVGAGLYKTGNPVENAKNLKYLARV
HHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKISASILATKLTELVKTVPNYDPTAIDLIHMDVMDGNFVPQISFGEALTKEVKSLTSIP
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
LDVHLMVAKPENHVFKYYEFNPYCITFHIETTDFPIRLAQEIKSHGTKVGVSLNPGTPVS
EEEEEEEECCCCCEEEEEEECCEEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHH
SLENVLPYVDLILLMTVEPGFYGQKFIINGMDKIRKVKELIGSRPIELEVDGGVNDTNIQ
HHHHHHHHHHHHHHEEECCCCCCCHHEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
ELRKNGVDIVVVGAGLYKTGNPVENAKNLKYLARV
HHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]