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The map label for this gene is ntrY [H]

Identifier: 45657421

GI number: 45657421

Start: 1909889

End: 1911679

Strand: Direct

Name: ntrY [H]

Synonym: LIC11548

Alternate gene names: 45657421

Gene position: 1909889-1911679 (Clockwise)

Preceding gene: 45657420

Following gene: 45657422

Centisome position: 44.65

GC content: 34.0

Gene sequence:

>1791_bases
ATGAATGACGAAACTAGATATTATCTAAGAGACTTACTCATCTTAGGTCTAATCATTTTACTTTCGGTAGTTCTCGCCGA
GGCAATTCAGTTTTCAGATCAAAAAACAATTCCGGACGATATAAGTTTTTTAGATAGAATTGTAGTTTATATTTTCTTTT
TTATTCCACTTTTTTCTCTTTCACTTCTTATTTCTTATTTTTATAGAAACAAAAGAAACCTAGAAACTGGAAGACTCAAA
AGTTCTATTAGGTATCGTCTAACGTTATCTTTTATATTTGTGGCATTTTTACCTTCCTTACCAATTTTATTTCTTTCTTC
TAATGTGACCGGAAAACTCTACGAAAGATTCTACGGAATTGATATTGAAGAAGCACTTTCTTCGGGAGAAACATTGATCT
TAAATGAAGAAAAACCTAAAAAACGATTACTCGTTGAAAAAACCAGACTTTTGGAAAGTTTTTTAAGAATACAACCTCTC
CATTTAGAATCTTTGGTCGCAGGCGCGTCTAAACTCAATTTGATTCAGAATGACGAATTTTACGTAGGAATTTATGAAAA
GGAAAAACCGATTTTAGAAAATAGAGCTTTGAAATATAGGCCCTTGGAAAAAAATTTTAAAATTTTTGCGAAAACTTCTA
ATTGGAAAGAATTTGCAAGTTATCGTCCCGATTATTGTATGTATTTTATTCGAATTCCTTTTCCAACAGGGAATTATAAT
CTTCAAACTGGAATTAGAATTCATAAAGACTCTGAGAGGAACGTATATTCAGTAATTTCTACGAGAAGAAATTACGATCG
CGCGGATTTAACTAAAGAAAAACTTCCTTATCGAATTCGTCTAACGTTTAGTATAATAACAGTTGCTATCTTTCTACTCG
CCATTTATTTTTCCCTTCTTTTTGCGAGAAAAATCTCTAGACCAATTATAGAATTAGCGAATGCGACTCAAAAAATTTCT
ATGGGAGATACTGACATCAATCTTGAAATTAGAGAGGCTGGTGAGATAGGCGCACTTATAGATTCTTTTAATCAGATGGT
AAAAGATTTAAAATCGAAGGACGCAGAACTCATGCAAAGCCAAAGGATCGCCGCTTGGAAAGAAGTGGCACAAAGGATGG
CTCATGAAATTAAAAATCCTCTTACTCCGATCCAACTTTCCGCTGAGAGAATTCGTAGAAAGATGAATTCTGAAAATAAA
GAACAGTTTTATGAAATTGTTTCTAGTGGGACCGATACGATCATCAAACAAGTTCGCGTGCTAGAACATCTTGTAAATGA
GTTTTCGGATTTTGCTCGTATGCCTGCCCCTAAGCTTATCAATCAGAATTTAGAGCCTATTCTTCTCGAAGTGGTGAAGT
TATTTGAACATACTCCTAAACTTAAAATTGCGACGAACATCTCAAAGGGATTTCCGCAACTATTTTTGGATCAAAAAATC
ATTTCTAGAGTTTTTACAAATCTATTGAAAAATTCAATCGAAGCCATAGAAAGAAAAAGAGAAAAAGAAGAAATACCAGA
ATACGAAGGTTCAATTCGAATCTCAGCTGTTCTGTCAAGGAAGATTATGAGAAAGGTCGCGGTGATTTCTATAGAAGATA
ACGGAATCGGAATTTCACCCGAACTCAAACAAAAAGTTTTCGAACCGTACTATTCCACTAAGAACAACAATACTTCTGGA
ATCGGTTTGGCGATTGTTCAAAAAAGTGTGATTGACCACAACGGTCATATCTCTGTAGATTCTTCCAGTATGGGAGGATG
TAGTTTTCAAATAGAACTTCCAGTGTCTTAA

Upstream 100 bases:

>100_bases
AACGAATTTAAAATTCAAGTAGAAGGTGAAAAGGAAGACGAGGCACTGGAGGCGCTAAGTAATATCGTAAATAACGATTT
CGTTTAATAAATTCGAAACC

Downstream 100 bases:

>100_bases
AACGATCATGAAAATTTTTATCGCAGACGATGAACCAGAAATCAGAAAATCTCTTAAAGAAATTTTAGAGGACGAAAATT
TCGAAGTAGAAACTTTCGCT

Product: histidine kinase sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MNDETRYYLRDLLILGLIILLSVVLAEAIQFSDQKTIPDDISFLDRIVVYIFFFIPLFSLSLLISYFYRNKRNLETGRLK
SSIRYRLTLSFIFVAFLPSLPILFLSSNVTGKLYERFYGIDIEEALSSGETLILNEEKPKKRLLVEKTRLLESFLRIQPL
HLESLVAGASKLNLIQNDEFYVGIYEKEKPILENRALKYRPLEKNFKIFAKTSNWKEFASYRPDYCMYFIRIPFPTGNYN
LQTGIRIHKDSERNVYSVISTRRNYDRADLTKEKLPYRIRLTFSIITVAIFLLAIYFSLLFARKISRPIIELANATQKIS
MGDTDINLEIREAGEIGALIDSFNQMVKDLKSKDAELMQSQRIAAWKEVAQRMAHEIKNPLTPIQLSAERIRRKMNSENK
EQFYEIVSSGTDTIIKQVRVLEHLVNEFSDFARMPAPKLINQNLEPILLEVVKLFEHTPKLKIATNISKGFPQLFLDQKI
ISRVFTNLLKNSIEAIERKREKEEIPEYEGSIRISAVLSRKIMRKVAVISIEDNGIGISPELKQKVFEPYYSTKNNNTSG
IGLAIVQKSVIDHNGHISVDSSSMGGCSFQIELPVS

Sequences:

>Translated_596_residues
MNDETRYYLRDLLILGLIILLSVVLAEAIQFSDQKTIPDDISFLDRIVVYIFFFIPLFSLSLLISYFYRNKRNLETGRLK
SSIRYRLTLSFIFVAFLPSLPILFLSSNVTGKLYERFYGIDIEEALSSGETLILNEEKPKKRLLVEKTRLLESFLRIQPL
HLESLVAGASKLNLIQNDEFYVGIYEKEKPILENRALKYRPLEKNFKIFAKTSNWKEFASYRPDYCMYFIRIPFPTGNYN
LQTGIRIHKDSERNVYSVISTRRNYDRADLTKEKLPYRIRLTFSIITVAIFLLAIYFSLLFARKISRPIIELANATQKIS
MGDTDINLEIREAGEIGALIDSFNQMVKDLKSKDAELMQSQRIAAWKEVAQRMAHEIKNPLTPIQLSAERIRRKMNSENK
EQFYEIVSSGTDTIIKQVRVLEHLVNEFSDFARMPAPKLINQNLEPILLEVVKLFEHTPKLKIATNISKGFPQLFLDQKI
ISRVFTNLLKNSIEAIERKREKEEIPEYEGSIRISAVLSRKIMRKVAVISIEDNGIGISPELKQKVFEPYYSTKNNNTSG
IGLAIVQKSVIDHNGHISVDSSSMGGCSFQIELPVS
>Mature_596_residues
MNDETRYYLRDLLILGLIILLSVVLAEAIQFSDQKTIPDDISFLDRIVVYIFFFIPLFSLSLLISYFYRNKRNLETGRLK
SSIRYRLTLSFIFVAFLPSLPILFLSSNVTGKLYERFYGIDIEEALSSGETLILNEEKPKKRLLVEKTRLLESFLRIQPL
HLESLVAGASKLNLIQNDEFYVGIYEKEKPILENRALKYRPLEKNFKIFAKTSNWKEFASYRPDYCMYFIRIPFPTGNYN
LQTGIRIHKDSERNVYSVISTRRNYDRADLTKEKLPYRIRLTFSIITVAIFLLAIYFSLLFARKISRPIIELANATQKIS
MGDTDINLEIREAGEIGALIDSFNQMVKDLKSKDAELMQSQRIAAWKEVAQRMAHEIKNPLTPIQLSAERIRRKMNSENK
EQFYEIVSSGTDTIIKQVRVLEHLVNEFSDFARMPAPKLINQNLEPILLEVVKLFEHTPKLKIATNISKGFPQLFLDQKI
ISRVFTNLLKNSIEAIERKREKEEIPEYEGSIRISAVLSRKIMRKVAVISIEDNGIGISPELKQKVFEPYYSTKNNNTSG
IGLAIVQKSVIDHNGHISVDSSSMGGCSFQIELPVS

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789808, Length=318, Percent_Identity=27.0440251572327, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=25.4681647940075, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790346, Length=302, Percent_Identity=24.1721854304636, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787894, Length=332, Percent_Identity=22.289156626506, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=305, Percent_Identity=27.2131147540984, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=26.6129032258064, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790300, Length=246, Percent_Identity=26.4227642276423, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081816, Length=358, Percent_Identity=24.8603351955307, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786783, Length=326, Percent_Identity=23.9263803680982, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=265, Percent_Identity=27.1698113207547, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68748; Mature: 68748

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDETRYYLRDLLILGLIILLSVVLAEAIQFSDQKTIPDDISFLDRIVVYIFFFIPLFSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLLISYFYRNKRNLETGRLKSSIRYRLTLSFIFVAFLPSLPILFLSSNVTGKLYERFYGI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCC
DIEEALSSGETLILNEEKPKKRLLVEKTRLLESFLRIQPLHLESLVAGASKLNLIQNDEF
CHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHCEEECCCE
YVGIYEKEKPILENRALKYRPLEKNFKIFAKTSNWKEFASYRPDYCMYFIRIPFPTGNYN
EEEEECCCCCHHHCCCCCCCCCCCCCEEEEECCCHHHHHHCCCCEEEEEEEECCCCCCCE
LQTGIRIHKDSERNVYSVISTRRNYDRADLTKEKLPYRIRLTFSIITVAIFLLAIYFSLL
EEECEEEECCCCCHHHHHHHHHCCCCHHHCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHH
FARKISRPIIELANATQKISMGDTDINLEIREAGEIGALIDSFNQMVKDLKSKDAELMQS
HHHHHHHHHHHHHCCHHEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIAAWKEVAQRMAHEIKNPLTPIQLSAERIRRKMNSENKEQFYEIVSSGTDTIIKQVRV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
LEHLVNEFSDFARMPAPKLINQNLEPILLEVVKLFEHTPKLKIATNISKGFPQLFLDQKI
HHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHH
ISRVFTNLLKNSIEAIERKREKEEIPEYEGSIRISAVLSRKIMRKVAVISIEDNGIGISP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHEEEEEECCCCCCCH
ELKQKVFEPYYSTKNNNTSGIGLAIVQKSVIDHNGHISVDSSSMGGCSFQIELPVS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCC
>Mature Secondary Structure
MNDETRYYLRDLLILGLIILLSVVLAEAIQFSDQKTIPDDISFLDRIVVYIFFFIPLFSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLLISYFYRNKRNLETGRLKSSIRYRLTLSFIFVAFLPSLPILFLSSNVTGKLYERFYGI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCC
DIEEALSSGETLILNEEKPKKRLLVEKTRLLESFLRIQPLHLESLVAGASKLNLIQNDEF
CHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHCEEECCCE
YVGIYEKEKPILENRALKYRPLEKNFKIFAKTSNWKEFASYRPDYCMYFIRIPFPTGNYN
EEEEECCCCCHHHCCCCCCCCCCCCCEEEEECCCHHHHHHCCCCEEEEEEEECCCCCCCE
LQTGIRIHKDSERNVYSVISTRRNYDRADLTKEKLPYRIRLTFSIITVAIFLLAIYFSLL
EEECEEEECCCCCHHHHHHHHHCCCCHHHCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHH
FARKISRPIIELANATQKISMGDTDINLEIREAGEIGALIDSFNQMVKDLKSKDAELMQS
HHHHHHHHHHHHHCCHHEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIAAWKEVAQRMAHEIKNPLTPIQLSAERIRRKMNSENKEQFYEIVSSGTDTIIKQVRV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
LEHLVNEFSDFARMPAPKLINQNLEPILLEVVKLFEHTPKLKIATNISKGFPQLFLDQKI
HHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHH
ISRVFTNLLKNSIEAIERKREKEEIPEYEGSIRISAVLSRKIMRKVAVISIEDNGIGISP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHEEEEEECCCCCCCH
ELKQKVFEPYYSTKNNNTSGIGLAIVQKSVIDHNGHISVDSSSMGGCSFQIELPVS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]