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The map label for this gene is xerD

Identifier: 45657354

GI number: 45657354

Start: 1827759

End: 1828655

Strand: Direct

Name: xerD

Synonym: LIC11479

Alternate gene names: 45657354

Gene position: 1827759-1828655 (Clockwise)

Preceding gene: 45657350

Following gene: 45657355

Centisome position: 42.73

GC content: 34.78

Gene sequence:

>897_bases
GTGACATCTTCACATAACAACCTACTTCAAAATTTTCAAGAATATCTCTCGGTAGAAAAGGGACTTAGCGACAATTCGAT
ATATTCCTATGGATACGATTTGAACAAGTTCAAGAACTTTCTAGAAAAAGAACATATAGATTTCTTAAAAGTTCAAGCGG
ACGATATTATGCGATTTTTGAACGAGGAAAAAGATCGTAAGATCAGCTCTAAAACGATCGCAAGAGAAGTGGTAGCCATT
AGACAGTTTTATAAGTTTCTAAAGGACGAGAAAAAGTTAGATACCAACCCGACTGAAAAAATAGAAACTCCCGAAGTGAT
GAGGAGTATTCCAGATTATCTGACTCAAGATGAAATTGAAGAATTGTTTGCTAGTATCAAAGAAGATAATCTTTATGAAC
TTAGAGACAAATGTATTTTTGAATTACTTTATTCTTCGGGCTTAAGAATTTCAGAGGCCTGCAATTTAAGATTAAACGAC
ATGGATCTAGAGGGAATGACCTTAACTGTTGAAGGCAAAGGAGGGCGTCAAAGACTAGTTCCTTTCGGAGAAAAATCCTT
GGATATTCTGAATCGTTATCTGAAACAGAGTCGTCCTTTTATTCTCAAATCTAGAAACTGTGAATATTTGTTCGTTTCTA
AAAAAGGTTCTTATATTAATCGTAAATCTGTTTGGAGACTTCTCAACCATTATATCAAAAGAACTTCTATCTTAAAAAAA
GTAACTCCACATACTCTTAGACACTCTTTTGCGACTCATTTGCTGGAAAATCACGCGGATCTAAAATCGGTTCAAGAACT
GTTGGGACATATTGATATTGCTACGACCCAGATATATACTCATATGGCCAACAAAACTCTGAGAGAAGTTCATAAAAAAT
TTCACCCTAGAGGATAG

Upstream 100 bases:

>100_bases
CAATAAACCCTTTAGGCAACATAAAAAAGTTTAATTCTCCTGAGGGGAAATGTCCGAAGGATTTAGTACTTGTTAAACAT
TTCAGACGGGACTAAAAGCA

Downstream 100 bases:

>100_bases
ATAGTTAAACCTAAATTTAAAAAAGAATGATAGTAAGAGTTTAAAAAATATTTTTAATATTCTAGAAAATCAATAGAGTT
TTTGAAAAATGAATTCTCCA

Product: putative integrase/recombinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTSSHNNLLQNFQEYLSVEKGLSDNSIYSYGYDLNKFKNFLEKEHIDFLKVQADDIMRFLNEEKDRKISSKTIAREVVAI
RQFYKFLKDEKKLDTNPTEKIETPEVMRSIPDYLTQDEIEELFASIKEDNLYELRDKCIFELLYSSGLRISEACNLRLND
MDLEGMTLTVEGKGGRQRLVPFGEKSLDILNRYLKQSRPFILKSRNCEYLFVSKKGSYINRKSVWRLLNHYIKRTSILKK
VTPHTLRHSFATHLLENHADLKSVQELLGHIDIATTQIYTHMANKTLREVHKKFHPRG

Sequences:

>Translated_298_residues
MTSSHNNLLQNFQEYLSVEKGLSDNSIYSYGYDLNKFKNFLEKEHIDFLKVQADDIMRFLNEEKDRKISSKTIAREVVAI
RQFYKFLKDEKKLDTNPTEKIETPEVMRSIPDYLTQDEIEELFASIKEDNLYELRDKCIFELLYSSGLRISEACNLRLND
MDLEGMTLTVEGKGGRQRLVPFGEKSLDILNRYLKQSRPFILKSRNCEYLFVSKKGSYINRKSVWRLLNHYIKRTSILKK
VTPHTLRHSFATHLLENHADLKSVQELLGHIDIATTQIYTHMANKTLREVHKKFHPRG
>Mature_297_residues
TSSHNNLLQNFQEYLSVEKGLSDNSIYSYGYDLNKFKNFLEKEHIDFLKVQADDIMRFLNEEKDRKISSKTIAREVVAIR
QFYKFLKDEKKLDTNPTEKIETPEVMRSIPDYLTQDEIEELFASIKEDNLYELRDKCIFELLYSSGLRISEACNLRLNDM
DLEGMTLTVEGKGGRQRLVPFGEKSLDILNRYLKQSRPFILKSRNCEYLFVSKKGSYINRKSVWRLLNHYIKRTSILKKV
TPHTLRHSFATHLLENHADLKSVQELLGHIDIATTQIYTHMANKTLREVHKKFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=36.0824742268041, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1790244, Length=300, Percent_Identity=31.6666666666667, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1790768, Length=169, Percent_Identity=28.9940828402367, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=28.4883720930233, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERD_LEPIC (Q72SA5)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_001440.1
- ProteinModelPortal:   Q72SA5
- SMR:   Q72SA5
- GeneID:   2769619
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC11479
- HOGENOM:   HBG727654
- OMA:   RTLAMIC
- ProtClustDB:   CLSK574439
- BioCyc:   LINT267671:LIC_11479-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01807
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02225

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 35074; Mature: 34943

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: ACT_SITE 149-149 ACT_SITE 173-173 ACT_SITE 244-244 ACT_SITE 247-247 ACT_SITE 270-270 ACT_SITE 279-279

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSHNNLLQNFQEYLSVEKGLSDNSIYSYGYDLNKFKNFLEKEHIDFLKVQADDIMRFL
CCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEEKDRKISSKTIAREVVAIRQFYKFLKDEKKLDTNPTEKIETPEVMRSIPDYLTQDEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHH
ELFASIKEDNLYELRDKCIFELLYSSGLRISEACNLRLNDMDLEGMTLTVEGKGGRQRLV
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCEECCCCCCCEEEEEECCCCCCCCC
PFGEKSLDILNRYLKQSRPFILKSRNCEYLFVSKKGSYINRKSVWRLLNHYIKRTSILKK
CCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
VTPHTLRHSFATHLLENHADLKSVQELLGHIDIATTQIYTHMANKTLREVHKKFHPRG
HCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSSHNNLLQNFQEYLSVEKGLSDNSIYSYGYDLNKFKNFLEKEHIDFLKVQADDIMRFL
CCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEEKDRKISSKTIAREVVAIRQFYKFLKDEKKLDTNPTEKIETPEVMRSIPDYLTQDEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHH
ELFASIKEDNLYELRDKCIFELLYSSGLRISEACNLRLNDMDLEGMTLTVEGKGGRQRLV
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCEECCCCCCCEEEEEECCCCCCCCC
PFGEKSLDILNRYLKQSRPFILKSRNCEYLFVSKKGSYINRKSVWRLLNHYIKRTSILKK
CCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
VTPHTLRHSFATHLLENHADLKSVQELLGHIDIATTQIYTHMANKTLREVHKKFHPRG
HCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA