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The map label for this gene is bacA

Identifier: 45657332

GI number: 45657332

Start: 1796747

End: 1797580

Strand: Direct

Name: bacA

Synonym: LIC11457

Alternate gene names: 45657332

Gene position: 1796747-1797580 (Clockwise)

Preceding gene: 45657331

Following gene: 45657333

Centisome position: 42.01

GC content: 33.57

Gene sequence:

>834_bases
TTGAATCCGTATCTGAACGCCTTTCTGAGAAGTATCATTGAGGCGATCACAGAATTTTTACCAGTGTCTTCCACAGGACA
TCTTTTTTTATTCAGTTCTTTTTTTCCCTTTTACGGAGAGAATGTAGAATTTGATGACCTTTTTGATATATTCATTCAGA
GTGGTGCGATTCTTTCTGTTTTATTTTTATATAGAGAGAAATTCAAGTCGCAGATTGTTTCTTCTTTTCGATATATTTTA
AAACAAAATTCAGATTCAGAAGGTTTTCATTTTTTAATTCAAATTTGTATTGGCGCTTTTCCGATTTTAATCGCTGGTTT
TATCGCGAAGAAGTTTTTAGATACGATCAAAGCAAGACCGGATCTTTTAGAGATTCTTTCGGGAGCTTGGATTTTTGGAG
GAGTTCTCATTCTAGTTGCAGAATGGTATTTTCATCAAAGACCGGAAGAAAAAAAATCAATTGGTTTTAAGGATTCTATT
CTGATTGGAATTTTTCAATGTATGGCTTTGATTCCAGGAATGTCTAGATCAGCTGCTACGATCATTACAGCTCGTTTTTT
AGGAAAGGATACTAAAAGTAGTGCTGAGTTTTCTTTTTTTCTTGCCGTTCCGGTTCTTCTTGCAGCAGGAATTTATAAAT
TAATTAAATATCGATCTATTCTAAATGGGAATACGATACCAGTATTGATGTTTGGTTTTTTAGTTTCATTTCTTCTTTGT
ACTTTGGTGATTCGTTGGTTTTTACGTTATATACAAAAACATTCTTTTAGCGTTTTCGGAGTTTATAGAATCTTGTTGGG
GGTCGGAGTTCTCGTTCTCACTAAGTTGATTTGA

Upstream 100 bases:

>100_bases
GAAAAAAATAGGCGGTGAGGCGGATAAAAAAGAATCTTCGTCTGCAACAGGAACTGCTCCTAAAACGGAAACTCCTAAAA
CTACTGGGCAGTAATTTCAA

Downstream 100 bases:

>100_bases
TGAGGAGAATAATCTGACACGGTATGCCTCTCCGTCTGGTTCTGATTTTATCTTTGTTACTGATCAAGATTCCTATCTAT
GCTCAGTCTACGGATGAACA

Product: bacitracin resistance protein

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MNPYLNAFLRSIIEAITEFLPVSSTGHLFLFSSFFPFYGENVEFDDLFDIFIQSGAILSVLFLYREKFKSQIVSSFRYIL
KQNSDSEGFHFLIQICIGAFPILIAGFIAKKFLDTIKARPDLLEILSGAWIFGGVLILVAEWYFHQRPEEKKSIGFKDSI
LIGIFQCMALIPGMSRSAATIITARFLGKDTKSSAEFSFFLAVPVLLAAGIYKLIKYRSILNGNTIPVLMFGFLVSFLLC
TLVIRWFLRYIQKHSFSVFGVYRILLGVGVLVLTKLI

Sequences:

>Translated_277_residues
MNPYLNAFLRSIIEAITEFLPVSSTGHLFLFSSFFPFYGENVEFDDLFDIFIQSGAILSVLFLYREKFKSQIVSSFRYIL
KQNSDSEGFHFLIQICIGAFPILIAGFIAKKFLDTIKARPDLLEILSGAWIFGGVLILVAEWYFHQRPEEKKSIGFKDSI
LIGIFQCMALIPGMSRSAATIITARFLGKDTKSSAEFSFFLAVPVLLAAGIYKLIKYRSILNGNTIPVLMFGFLVSFLLC
TLVIRWFLRYIQKHSFSVFGVYRILLGVGVLVLTKLI
>Mature_277_residues
MNPYLNAFLRSIIEAITEFLPVSSTGHLFLFSSFFPFYGENVEFDDLFDIFIQSGAILSVLFLYREKFKSQIVSSFRYIL
KQNSDSEGFHFLIQICIGAFPILIAGFIAKKFLDTIKARPDLLEILSGAWIFGGVLILVAEWYFHQRPEEKKSIGFKDSI
LIGIFQCMALIPGMSRSAATIITARFLGKDTKSSAEFSFFLAVPVLLAAGIYKLIKYRSILNGNTIPVLMFGFLVSFLLC
TLVIRWFLRYIQKHSFSVFGVYRILLGVGVLVLTKLI

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=278, Percent_Identity=33.8129496402878, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_LEPIC (P62465)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_001418.1
- GeneID:   2771065
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC11457
- HOGENOM:   HBG391969
- OMA:   HDVIKTY
- ProtClustDB:   CLSK574452
- BioCyc:   LINT-130-01:LINT-130-01-001418-MONOMER
- BioCyc:   LINT267671:LIC_11457-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 31375; Mature: 31375

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10403b28)-; HASH(0xfe6f47c)-; HASH(0xfeb63a4)-; HASH(0x107cb8bc)-; HASH(0xfd05d88)-; HASH(0xd79b804)-; HASH(0x107cb52c)-; HASH(0xf274504)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure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HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA