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The map label for this gene is crp [C]

Identifier: 45657307

GI number: 45657307

Start: 1758452

End: 1758928

Strand: Direct

Name: crp [C]

Synonym: LIC11431

Alternate gene names: 45657307

Gene position: 1758452-1758928 (Clockwise)

Preceding gene: 45657305

Following gene: 45657309

Centisome position: 41.11

GC content: 35.22

Gene sequence:

>477_bases
ATGCAACATACGAAAGAAGAAATTTTAAAACAGATTTATCTTTTCTCCAATTTTACGGAAGACGAATTAAACTCTATTGC
GGAGAAAACGGAATATAAAGTTTACGAACAAGGCGATTCGATTTTTCACGAAGGAAATGAAGCGAAAGCCTTTTTTGTAG
TGATTTACGGAACTCTAAAGGTACTTACTTCTACTGAAAAAGGGGACGATGTCAACGTAACTACGATTGCGACTGGAGAT
CATTTTGGTGAATTACCGTTTTTAGATCCTGGAAAACGTTCTGCATCTGTAGAAGCGATGGAAAGATCTGAACTTTTAAG
AATTCCTTACGATCATTTAAAAGCGGTTTTTGAAAAGGATTCTAATGCTTCCTTAAAATTTTACCAGGCGATTTCTCATT
TTTTAGCGAAACGTTTGAGAATGTTAACTCATGATTTAGCCTACGCACGAGAACTCAGAAAAAGATATACGATTTGA

Upstream 100 bases:

>100_bases
GCGGTTTGTCTAAAAATCAGAGGACATTTTTGTATATCTATACATCTAACCTGCTTGCATTTATTTAAACTGAGATTTAC
ACTCACATTTCGAGAATATT

Downstream 100 bases:

>100_bases
TTTTTTAAAAACCGTATTTCTAAAATTTAAAGGAGTTTGGATGGATATAAATTCAAACTCCTAAATTTATTTTTTTTAAG
ACTGAAATAAAAGAACGATT

Product: cyclic nucleotide binding protein

Products: NA

Alternate protein names: Transcriptional Regulator Crp/Fnr Family; Phosphoprotein Phosphatase; CRP/FNR Family Transcriptional Regulator; CAMP-Dependent Protein Kinase Regulatory Subunit; CAMP-Dependent Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MQHTKEEILKQIYLFSNFTEDELNSIAEKTEYKVYEQGDSIFHEGNEAKAFFVVIYGTLKVLTSTEKGDDVNVTTIATGD
HFGELPFLDPGKRSASVEAMERSELLRIPYDHLKAVFEKDSNASLKFYQAISHFLAKRLRMLTHDLAYARELRKRYTI

Sequences:

>Translated_158_residues
MQHTKEEILKQIYLFSNFTEDELNSIAEKTEYKVYEQGDSIFHEGNEAKAFFVVIYGTLKVLTSTEKGDDVNVTTIATGD
HFGELPFLDPGKRSASVEAMERSELLRIPYDHLKAVFEKDSNASLKFYQAISHFLAKRLRMLTHDLAYARELRKRYTI
>Mature_158_residues
MQHTKEEILKQIYLFSNFTEDELNSIAEKTEYKVYEQGDSIFHEGNEAKAFFVVIYGTLKVLTSTEKGDDVNVTTIATGD
HFGELPFLDPGKRSASVEAMERSELLRIPYDHLKAVFEKDSNASLKFYQAISHFLAKRLRMLTHDLAYARELRKRYTI

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 18261; Mature: 18261

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHTKEEILKQIYLFSNFTEDELNSIAEKTEYKVYEQGDSIFHEGNEAKAFFVVIYGTLK
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEHHHH
VLTSTEKGDDVNVTTIATGDHFGELPFLDPGKRSASVEAMERSELLRIPYDHLKAVFEKD
HHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCC
SNASLKFYQAISHFLAKRLRMLTHDLAYARELRKRYTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQHTKEEILKQIYLFSNFTEDELNSIAEKTEYKVYEQGDSIFHEGNEAKAFFVVIYGTLK
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEHHHH
VLTSTEKGDDVNVTTIATGDHFGELPFLDPGKRSASVEAMERSELLRIPYDHLKAVFEKD
HHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCC
SNASLKFYQAISHFLAKRLRMLTHDLAYARELRKRYTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA