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The map label for this gene is capB

Identifier: 45657303

GI number: 45657303

Start: 1753836

End: 1755059

Strand: Direct

Name: capB

Synonym: LIC11427

Alternate gene names: 45657303

Gene position: 1753836-1755059 (Clockwise)

Preceding gene: 45657302

Following gene: 45657304

Centisome position: 41.0

GC content: 33.74

Gene sequence:

>1224_bases
ATGTCTTTTTTTATTTTAAGTTTTCTATTTTTAGTTTTTTGTGCCTTTCTTTTTTTAGAGAAAAAAAGTCATGACCAAAT
ATTAAAACGAATTCCAATTCGAATTCACGTCAACGGAACCAGAGGAAAATCTTCTGTAACTCGGTTGATTCATTCCATTT
TGGTAGAGGAGGGCTGGAAGGTTTTTGCAAAAACTACCGGGTCTACCGCCAGTCTTTTATTTCCAAATCGAAGTGAAAGT
TTTATATTTAGAAATAAAATTTCTATCGAAGAACAAAAATCTTTTCTTCGTTTTGCTGTGAACAATGACGCGCAAGCGAT
CGTTTTGGAGTGTATGGCAGTTCAACCCCAATATCAGAGAGATTCGGAAGAGTTATTGATCTGTGCCACTCATGGCGTAA
TTACGAATATTCGTCCAGACCATTGGGAATGGACGGATACGGAAGAAAAAATCTTAGAAGGTTTTAAAAAAACAATTCCT
AATAATGGAATTCTAATATATGGAAAAAATTATATAGCTGAGAGTTTAAAACCAAATTGGAATCCAAGTCAAAAATCGAA
ACTAAATTTAAGTCTTTTGGAAGCTGCTTCTTTAAAAAATACAAAATTGATTCTTGCGGAACCCGAACTTTCTAAAAATC
AAATTGAAACTGCATTCGGATATATACGTTATCCGGAACATTATGAAAACGTGGAAATCGCTGTTCGTGTTTGTGAAACA
TTAGGCGTATCTTCTAAATCCATTTTACGAGGAATTACAAACACTGTCTCCGATCCGGGAGCGCTTAAAATTTTGGAAAA
AGAAGTCAAAGGTAAGCGCCAAAGGTTTGTATTTGCGTTTGCTGCCAACGACGTAGTTTCCTTTGAAAAAATTTTAAAAT
CCGATCAAAAAAAATGGAGTGAATTCGATTCTATCATTTTAGTTTTTAATTCCAAGCAAGAAAGGCCGTTTAGAACCATT
GAGTTTGGTAAATTTTTAACGGATTTTTCTGGCCTTTCAAAAATTTATTTTTTTGGTTCTTGGCAAAAATTATTTCGATC
CGTATATGAAGGAAATGCAGATTTAACCTTTTATAAGAAAAATATTATATTCAATTTTAAAGAAATTTTTTCTAAGTCCA
ATCTATGGATAGGAGCCGGAAACTATCAAGGTTTTGGAAGAGTTTGGTTGGAGAAGTTGGCGGCAGATCTAAACGTGATA
GAGGGGAAAGGTTGGAAATCTTAA

Upstream 100 bases:

>100_bases
CCGGCGATATTACAGAAACTGATCGATCATTTAGGTCAGCAAAAAATACAAGACGATATAACTGCGATTTTAATCGCTTT
AGATTTTCCCCATCTTTAAG

Downstream 100 bases:

>100_bases
CGTTATCGATCGGAGTTGGCGTTTTATTTGGTTTTTTCCTTTGGGAAAAAACTGGACTTCAACCTGGAGGTTGGGTAGTT
CCGGGTTACATTGCTTTTTT

Product: capsule biosynthesis protein

Products: NA

Alternate protein names: Gamma-polyglutamic acid synthase [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSFFILSFLFLVFCAFLFLEKKSHDQILKRIPIRIHVNGTRGKSSVTRLIHSILVEEGWKVFAKTTGSTASLLFPNRSES
FIFRNKISIEEQKSFLRFAVNNDAQAIVLECMAVQPQYQRDSEELLICATHGVITNIRPDHWEWTDTEEKILEGFKKTIP
NNGILIYGKNYIAESLKPNWNPSQKSKLNLSLLEAASLKNTKLILAEPELSKNQIETAFGYIRYPEHYENVEIAVRVCET
LGVSSKSILRGITNTVSDPGALKILEKEVKGKRQRFVFAFAANDVVSFEKILKSDQKKWSEFDSIILVFNSKQERPFRTI
EFGKFLTDFSGLSKIYFFGSWQKLFRSVYEGNADLTFYKKNIIFNFKEIFSKSNLWIGAGNYQGFGRVWLEKLAADLNVI
EGKGWKS

Sequences:

>Translated_407_residues
MSFFILSFLFLVFCAFLFLEKKSHDQILKRIPIRIHVNGTRGKSSVTRLIHSILVEEGWKVFAKTTGSTASLLFPNRSES
FIFRNKISIEEQKSFLRFAVNNDAQAIVLECMAVQPQYQRDSEELLICATHGVITNIRPDHWEWTDTEEKILEGFKKTIP
NNGILIYGKNYIAESLKPNWNPSQKSKLNLSLLEAASLKNTKLILAEPELSKNQIETAFGYIRYPEHYENVEIAVRVCET
LGVSSKSILRGITNTVSDPGALKILEKEVKGKRQRFVFAFAANDVVSFEKILKSDQKKWSEFDSIILVFNSKQERPFRTI
EFGKFLTDFSGLSKIYFFGSWQKLFRSVYEGNADLTFYKKNIIFNFKEIFSKSNLWIGAGNYQGFGRVWLEKLAADLNVI
EGKGWKS
>Mature_406_residues
SFFILSFLFLVFCAFLFLEKKSHDQILKRIPIRIHVNGTRGKSSVTRLIHSILVEEGWKVFAKTTGSTASLLFPNRSESF
IFRNKISIEEQKSFLRFAVNNDAQAIVLECMAVQPQYQRDSEELLICATHGVITNIRPDHWEWTDTEEKILEGFKKTIPN
NGILIYGKNYIAESLKPNWNPSQKSKLNLSLLEAASLKNTKLILAEPELSKNQIETAFGYIRYPEHYENVEIAVRVCETL
GVSSKSILRGITNTVSDPGALKILEKEVKGKRQRFVFAFAANDVVSFEKILKSDQKKWSEFDSIILVFNSKQERPFRTIE
FGKFLTDFSGLSKIYFFGSWQKLFRSVYEGNADLTFYKKNIIFNFKEIFSKSNLWIGAGNYQGFGRVWLEKLAADLNVIE
GKGWKS

Specific function: Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008337
- InterPro:   IPR013221 [H]

Pfam domain/function: PF08245 Mur_ligase_M [H]

EC number: NA

Molecular weight: Translated: 46759; Mature: 46628

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFILSFLFLVFCAFLFLEKKSHDQILKRIPIRIHVNGTRGKSSVTRLIHSILVEEGWK
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCCE
VFAKTTGSTASLLFPNRSESFIFRNKISIEEQKSFLRFAVNNDAQAIVLECMAVQPQYQR
EEEECCCCEEEEEECCCCCCEEEEECCCHHHHHHHHEEEECCCCCEEHHHHHHCCCCCCC
DSEELLICATHGVITNIRPDHWEWTDTEEKILEGFKKTIPNNGILIYGKNYIAESLKPNW
CCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCC
NPSQKSKLNLSLLEAASLKNTKLILAEPELSKNQIETAFGYIRYPEHYENVEIAVRVCET
CCCCCCCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHEEECCCHHCCHHHHHHHHHH
LGVSSKSILRGITNTVSDPGALKILEKEVKGKRQRFVFAFAANDVVSFEKILKSDQKKWS
HCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHEEEEEEECCCHHHHHHHHHHHHHHHH
EFDSIILVFNSKQERPFRTIEFGKFLTDFSGLSKIYFFGSWQKLFRSVYEGNADLTFYKK
HHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCEEEEEC
NIIFNFKEIFSKSNLWIGAGNYQGFGRVWLEKLAADLNVIEGKGWKS
HHEEEHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCEEECCCCCCC
>Mature Secondary Structure 
SFFILSFLFLVFCAFLFLEKKSHDQILKRIPIRIHVNGTRGKSSVTRLIHSILVEEGWK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCCE
VFAKTTGSTASLLFPNRSESFIFRNKISIEEQKSFLRFAVNNDAQAIVLECMAVQPQYQR
EEEECCCCEEEEEECCCCCCEEEEECCCHHHHHHHHEEEECCCCCEEHHHHHHCCCCCCC
DSEELLICATHGVITNIRPDHWEWTDTEEKILEGFKKTIPNNGILIYGKNYIAESLKPNW
CCCCEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCC
NPSQKSKLNLSLLEAASLKNTKLILAEPELSKNQIETAFGYIRYPEHYENVEIAVRVCET
CCCCCCCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHEEECCCHHCCHHHHHHHHHH
LGVSSKSILRGITNTVSDPGALKILEKEVKGKRQRFVFAFAANDVVSFEKILKSDQKKWS
HCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHEEEEEEECCCHHHHHHHHHHHHHHHH
EFDSIILVFNSKQERPFRTIEFGKFLTDFSGLSKIYFFGSWQKLFRSVYEGNADLTFYKK
HHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCEEEEEC
NIIFNFKEIFSKSNLWIGAGNYQGFGRVWLEKLAADLNVIEGKGWKS
HHEEEHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 10486244; 11751809; 9384377 [H]