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The map label for this gene is radA

Identifier: 45657026

GI number: 45657026

Start: 1408451

End: 1409830

Strand: Direct

Name: radA

Synonym: LIC11142

Alternate gene names: 45657026

Gene position: 1408451-1409830 (Clockwise)

Preceding gene: 45657025

Following gene: 45657027

Centisome position: 32.93

GC content: 42.1

Gene sequence:

>1380_bases
TTGAAAAAGAAACTCAGTCGAACTTTTATCTGTCAGTCCTGCGGTCAGGATTATACCCGCTGGGCTGGTAAATGTGAATC
CTGTGGGAGTTGGAATTCGATTGTAGAAGAGATTGGTGGTGAACGTTTCTCTTCTTCTAACGGAAGCTCTCAAAAAAACA
AATCGTATAAGGAACCGATTCCTTTAGACAGAGTAGAAGAAGAATCTCTGAAAAGGATGGGAACTGGTCTGAAAGAATTG
GATCTCGTTTTGGGAGGGGGACTTGTTCCCGGTTCTCTGACTTTGATCGGTGGAGAACCAGGTGTAGGTAAGTCCACTTT
GATTTTAGAAGTTTCACGTTATCTGACACAGGCGAATAAAAATGTTCTCTATATTTCTGGAGAAGAATCACCTTCTCAGA
TTCGAATGCGTGCTGAAAGGATGGGGCTTCGTGCTTCTAATCTTTTTGTTACATCGGAAACGATTGCTGAAAATATTTCT
TCGATGATTGAAGGAGAAAAACCCGCCGTCGTTTTTGTAGATTCGATTCAGACGATTGCAAGAGAAGCACTTCCTAATCA
AGCGGGGACTGTTACACAACTGAGAGAATGTACTCAAGTTTTATTGGAAACTGCAAAACGATCTGGAATTCCGATTTTAA
TGACCGGACATATTACCAAAGAAGGAACGATCGCTGGACCCAAAGTTCTAGAACATCTCGTGGATACGGTTCTTTATTTC
GAAGGAGATAGACTCAATTATTATCGTTTGCTTAGAGCAGTGAAAAATCGTTTTGGTGCAGTTGGTGATCTTGCAATTTT
TGAAATGTTTTCTGGTGGTTTAAGAGAAGTAGGGGATCGAAATCGTGTTTTTGTAAGTGCGGGAGCGGAAGAAAGAAGCG
GTTCTGTGATCAGCGCGGTGTTGGAAGGTAGCAGGGCACTTACTGTGGAAGTGCAGGCTTTGGTTAGTAAAACCGGTTTT
GCCCAAGCGAGGAGAATGGCGGAAGGTCCGGACACTCGTCGTGTGATCTTACTGGCCGCTGTAATCGAAAAGTATATTAA
AATCAAATTAGGAGAATGTGATCTATTTAGTAATCTCGCTGGAGGTTTGAGTGCGGATGAACCTGCTTTGGATCTTGCGA
TTTGTGCTTCGATTATATCCAGTTATCTGGATCAACCTCTTCCAAAAGGAACTTGTGTTTTAGGTGAGGTTGGACTTTCG
GGAGAAGTACGTAGTATTGGTCAGGCTAATCTTAGGGTTAAGGAGTTGGCTGGGGTTGGTATGAAGAAGGTAATTTTGCC
TGAGGGAAATTTAAGTGAATTGGATCAAAACTTAGATATACAAGTTAAAGGAATTCGTTCATTGAATGACCTTCGTTCTC
TTTTTCCGGGTGCCAGTTAA

Upstream 100 bases:

>100_bases
TAGTAAGAGAAGGTAGAGATTCCTTGGCAAGGGAAGCTTTTCGTTGTCTTCCTGTTTTTAATCAGATTGATTGGCTTGAA
ATGCCTACTCTTTTTGAACA

Downstream 100 bases:

>100_bases
ATTATATTTTTTGAATATTATTTTTTATATAATATAAATGTTGAAAAATTAATTCTCTATCTGTTTCTATTTTATGGAAA
TGGTCGATGGAAACAATTTT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKKKLSRTFICQSCGQDYTRWAGKCESCGSWNSIVEEIGGERFSSSNGSSQKNKSYKEPIPLDRVEEESLKRMGTGLKEL
DLVLGGGLVPGSLTLIGGEPGVGKSTLILEVSRYLTQANKNVLYISGEESPSQIRMRAERMGLRASNLFVTSETIAENIS
SMIEGEKPAVVFVDSIQTIAREALPNQAGTVTQLRECTQVLLETAKRSGIPILMTGHITKEGTIAGPKVLEHLVDTVLYF
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNRVFVSAGAEERSGSVISAVLEGSRALTVEVQALVSKTGF
AQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLAGGLSADEPALDLAICASIISSYLDQPLPKGTCVLGEVGLS
GEVRSIGQANLRVKELAGVGMKKVILPEGNLSELDQNLDIQVKGIRSLNDLRSLFPGAS

Sequences:

>Translated_459_residues
MKKKLSRTFICQSCGQDYTRWAGKCESCGSWNSIVEEIGGERFSSSNGSSQKNKSYKEPIPLDRVEEESLKRMGTGLKEL
DLVLGGGLVPGSLTLIGGEPGVGKSTLILEVSRYLTQANKNVLYISGEESPSQIRMRAERMGLRASNLFVTSETIAENIS
SMIEGEKPAVVFVDSIQTIAREALPNQAGTVTQLRECTQVLLETAKRSGIPILMTGHITKEGTIAGPKVLEHLVDTVLYF
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNRVFVSAGAEERSGSVISAVLEGSRALTVEVQALVSKTGF
AQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLAGGLSADEPALDLAICASIISSYLDQPLPKGTCVLGEVGLS
GEVRSIGQANLRVKELAGVGMKKVILPEGNLSELDQNLDIQVKGIRSLNDLRSLFPGAS
>Mature_459_residues
MKKKLSRTFICQSCGQDYTRWAGKCESCGSWNSIVEEIGGERFSSSNGSSQKNKSYKEPIPLDRVEEESLKRMGTGLKEL
DLVLGGGLVPGSLTLIGGEPGVGKSTLILEVSRYLTQANKNVLYISGEESPSQIRMRAERMGLRASNLFVTSETIAENIS
SMIEGEKPAVVFVDSIQTIAREALPNQAGTVTQLRECTQVLLETAKRSGIPILMTGHITKEGTIAGPKVLEHLVDTVLYF
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNRVFVSAGAEERSGSVISAVLEGSRALTVEVQALVSKTGF
AQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLAGGLSADEPALDLAICASIISSYLDQPLPKGTCVLGEVGLS
GEVRSIGQANLRVKELAGVGMKKVILPEGNLSELDQNLDIQVKGIRSLNDLRSLFPGAS

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=463, Percent_Identity=41.9006479481641, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49533; Mature: 49533

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLSRTFICQSCGQDYTRWAGKCESCGSWNSIVEEIGGERFSSSNGSSQKNKSYKEPI
CCCHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PLDRVEEESLKRMGTGLKELDLVLGGGLVPGSLTLIGGEPGVGKSTLILEVSRYLTQANK
CCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCC
NVLYISGEESPSQIRMRAERMGLRASNLFVTSETIAENISSMIEGEKPAVVFVDSIQTIA
CEEEEECCCCHHHHHHHHHHHCCCHHCEEEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
REALPNQAGTVTQLRECTQVLLETAKRSGIPILMTGHITKEGTIAGPKVLEHLVDTVLYF
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHH
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNRVFVSAGAEERSGSVISAV
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCHHHHHH
LEGSRALTVEVQALVSKTGFAQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLA
HCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHC
GGLSADEPALDLAICASIISSYLDQPLPKGTCVLGEVGLSGEVRSIGQANLRVKELAGVG
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHCCCCCCCHHHHHCCC
MKKVILPEGNLSELDQNLDIQVKGIRSLNDLRSLFPGAS
CEEEEECCCCHHHHCCCCCEEEECHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKKLSRTFICQSCGQDYTRWAGKCESCGSWNSIVEEIGGERFSSSNGSSQKNKSYKEPI
CCCHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PLDRVEEESLKRMGTGLKELDLVLGGGLVPGSLTLIGGEPGVGKSTLILEVSRYLTQANK
CCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCC
NVLYISGEESPSQIRMRAERMGLRASNLFVTSETIAENISSMIEGEKPAVVFVDSIQTIA
CEEEEECCCCHHHHHHHHHHHCCCHHCEEEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
REALPNQAGTVTQLRECTQVLLETAKRSGIPILMTGHITKEGTIAGPKVLEHLVDTVLYF
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHH
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNRVFVSAGAEERSGSVISAV
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCHHHHHH
LEGSRALTVEVQALVSKTGFAQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLA
HCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHC
GGLSADEPALDLAICASIISSYLDQPLPKGTCVLGEVGLSGEVRSIGQANLRVKELAGVG
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHCCCCCCCHHHHHCCC
MKKVILPEGNLSELDQNLDIQVKGIRSLNDLRSLFPGAS
CEEEEECCCCHHHHCCCCCEEEECHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]