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The map label for this gene is pkn1 [H]

Identifier: 45656756

GI number: 45656756

Start: 1044058

End: 1044879

Strand: Direct

Name: pkn1 [H]

Synonym: LIC10865

Alternate gene names: 45656756

Gene position: 1044058-1044879 (Clockwise)

Preceding gene: 45656755

Following gene: 45656759

Centisome position: 24.41

GC content: 41.97

Gene sequence:

>822_bases
ATGTTTTACATGTTCAAGATGGTAAAGAAATACGTCTCAACAATTTGTCTACTAATCGCGATATCGGTAGGCTCCACAAT
TTTTTCCAGACCATTATCCATTTCCGAAAAAAATCAAGAAGAAAAAATCAAGAATGATTTTCAGAGAGAATTCAGAATCG
AAAACTTCGTACTCATTCCCGCTGGAGAATTTGTCATGGGCTGCGTTGCCGGTGACCTACAGTGTGATGAGAGGGAGAAA
CCGCCCAAAGCCATGAAGATCGTCAAACCGTTCTACATGGGCAAATATGAAGTTACACAAACACAATGGCAACTTGTGAT
GCGCTATGATCAGAGTGATTTCAAGAAGTGTGGTGGTTCTTGCCCAGTGAACAACGTTACGTGGTTTAGTGTCCAGGTAT
TCTTAAAACAGCTAAATTATGCAATGCAAGAGCTTGGAAAGGCGACAATGGTCTTTCGATTACCGAATGAAGCGGAATGG
GAATATGCAGCCCGAGCTGGTTCGACTACAAAGTATTATTGGGGGGAAGAAATGGATCCAAATTACTTATGGTATTCCTC
AAATTCTGATTATAAAATTCATCCAGCTGGTCAAAAGAAACCTAACTCATTTGGCCTTTTTGACATGAACGGAAATGTCT
CTGAATGGACGGCAGACAGTTTTGTGGATCGCCATTCGAAGCGCAATGTCGAAATGCGCATCGTCCGCGGATGCAGTTGG
TTTAGTGAATCTGAGACTTGTCGTATTTCACATAGGAACGCTGGTGTACCAAGCTATGGCTCAAATATGGTTGGTTTTCG
GCTCATTCTGGAATTGCAGTAA

Upstream 100 bases:

>100_bases
TTTTGCGCTTAATCACTCATAACTTATCTTTTTGTTCCCCGGAGAATCATCAGGATTTACAGCCGTGATTCAGGGATTAA
CTGTGAATTAGTGAGGAGCA

Downstream 100 bases:

>100_bases
AAAATTGGTCTTTAATGTTTGACTACCCATAACTGGTCATTTTGCCCTCATCATTCACTGTGGTGATGGCTCAGAGATTA
AACAGTATCTGAGTGAGGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MFYMFKMVKKYVSTICLLIAISVGSTIFSRPLSISEKNQEEKIKNDFQREFRIENFVLIPAGEFVMGCVAGDLQCDEREK
PPKAMKIVKPFYMGKYEVTQTQWQLVMRYDQSDFKKCGGSCPVNNVTWFSVQVFLKQLNYAMQELGKATMVFRLPNEAEW
EYAARAGSTTKYYWGEEMDPNYLWYSSNSDYKIHPAGQKKPNSFGLFDMNGNVSEWTADSFVDRHSKRNVEMRIVRGCSW
FSESETCRISHRNAGVPSYGSNMVGFRLILELQ

Sequences:

>Translated_273_residues
MFYMFKMVKKYVSTICLLIAISVGSTIFSRPLSISEKNQEEKIKNDFQREFRIENFVLIPAGEFVMGCVAGDLQCDEREK
PPKAMKIVKPFYMGKYEVTQTQWQLVMRYDQSDFKKCGGSCPVNNVTWFSVQVFLKQLNYAMQELGKATMVFRLPNEAEW
EYAARAGSTTKYYWGEEMDPNYLWYSSNSDYKIHPAGQKKPNSFGLFDMNGNVSEWTADSFVDRHSKRNVEMRIVRGCSW
FSESETCRISHRNAGVPSYGSNMVGFRLILELQ
>Mature_273_residues
MFYMFKMVKKYVSTICLLIAISVGSTIFSRPLSISEKNQEEKIKNDFQREFRIENFVLIPAGEFVMGCVAGDLQCDEREK
PPKAMKIVKPFYMGKYEVTQTQWQLVMRYDQSDFKKCGGSCPVNNVTWFSVQVFLKQLNYAMQELGKATMVFRLPNEAEW
EYAARAGSTTKYYWGEEMDPNYLWYSSNSDYKIHPAGQKKPNSFGLFDMNGNVSEWTADSFVDRHSKRNVEMRIVRGCSW
FSESETCRISHRNAGVPSYGSNMVGFRLILELQ

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248088, Length=132, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI194248087, Length=136, Percent_Identity=32.3529411764706, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI226437577, Length=132, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31644; Mature: 31644

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYMFKMVKKYVSTICLLIAISVGSTIFSRPLSISEKNQEEKIKNDFQREFRIENFVLIP
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
AGEFVMGCVAGDLQCDEREKPPKAMKIVKPFYMGKYEVTQTQWQLVMRYDQSDFKKCGGS
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHCCHHHHHHCCCC
CPVNNVTWFSVQVFLKQLNYAMQELGKATMVFRLPNEAEWEYAARAGSTTKYYWGEEMDP
CCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCEEEECCCCCCC
NYLWYSSNSDYKIHPAGQKKPNSFGLFDMNGNVSEWTADSFVDRHSKRNVEMRIVRGCSW
CEEEECCCCCEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCC
FSESETCRISHRNAGVPSYGSNMVGFRLILELQ
CCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEC
>Mature Secondary Structure
MFYMFKMVKKYVSTICLLIAISVGSTIFSRPLSISEKNQEEKIKNDFQREFRIENFVLIP
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
AGEFVMGCVAGDLQCDEREKPPKAMKIVKPFYMGKYEVTQTQWQLVMRYDQSDFKKCGGS
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHCCHHHHHHCCCC
CPVNNVTWFSVQVFLKQLNYAMQELGKATMVFRLPNEAEWEYAARAGSTTKYYWGEEMDP
CCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCEEEECCCCCCC
NYLWYSSNSDYKIHPAGQKKPNSFGLFDMNGNVSEWTADSFVDRHSKRNVEMRIVRGCSW
CEEEECCCCCEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCC
FSESETCRISHRNAGVPSYGSNMVGFRLILELQ
CCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]