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The map label for this gene is tsf

Identifier: 45656742

GI number: 45656742

Start: 1027396

End: 1027995

Strand: Direct

Name: tsf

Synonym: LIC10851

Alternate gene names: 45656742

Gene position: 1027396-1027995 (Clockwise)

Preceding gene: 45656741

Following gene: 45656743

Centisome position: 24.02

GC content: 41.0

Gene sequence:

>600_bases
ATGGCAGCAGTGACTACGGACTTAATCAGAGAACTTAGAGAAAGAACCAGTGCAGGAATGATGGACTGTAAAAAGGCTCT
TGAAGAAAACAACGCAGATATTGAAAAAGCGATCACTTGGCTTCGTGAAAAAGGGATCGCAAAGGCGGCTAAAAAAGCGG
GAAGAGAAACCAAAGAAGGTAGAGTGGTTTCTTATATCCACGGAAACGGAAAGATCGGAGTTCTTGTAGAATTGAATTCC
GAAACAGATTTCGTTTCTAAAAACGAAGACTTTGAAGCCCTCGGTAAAGAAATCTGTATGCAGATCGCGGCGATGAATCC
TTTGTATCTCAACGAAGAATCCATTCCTGCTGCGGATCTGGAAAAAGAAAAAACGATCATGAGATCTCAATTGGAAGCGG
AAGGTAAAAAAGCCGATCAGATTGAAAAGATCCTTCCTGGAAAAATCAAAAAATACATTTCGGAAGTTTGTCTTGTAAAC
CAGGCATTTTTTAAAGACGATTCTAAAACCATAGACGACTTAGTAAAGGAAGCGATCGCGAAATTTGGCGAGAACATTAC
TATCGCCCGTTTTATCCGCTTTCAGGTGGGTGGACTCTAA

Upstream 100 bases:

>100_bases
ATTCTAAAAAAACTAAAACTGCGGAAGAACCTTCTGCTACGATCGAACCTTCTACTACCACTACGGTCGAAGTGGATCAA
AACGAATAAGGATTTCATTC

Downstream 100 bases:

>100_bases
GTTTTGGCTACGGAAGCGAAGTATAATAGAATTCTAATTAAGCTTTCCGGCGAGGCTCTCGCTGGAGAGGGTGAATTTGG
GATCGATACAAATAAGGCCC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAAVTTDLIRELRERTSAGMMDCKKALEENNADIEKAITWLREKGIAKAAKKAGRETKEGRVVSYIHGNGKIGVLVELNS
ETDFVSKNEDFEALGKEICMQIAAMNPLYLNEESIPAADLEKEKTIMRSQLEAEGKKADQIEKILPGKIKKYISEVCLVN
QAFFKDDSKTIDDLVKEAIAKFGENITIARFIRFQVGGL

Sequences:

>Translated_199_residues
MAAVTTDLIRELRERTSAGMMDCKKALEENNADIEKAITWLREKGIAKAAKKAGRETKEGRVVSYIHGNGKIGVLVELNS
ETDFVSKNEDFEALGKEICMQIAAMNPLYLNEESIPAADLEKEKTIMRSQLEAEGKKADQIEKILPGKIKKYISEVCLVN
QAFFKDDSKTIDDLVKEAIAKFGENITIARFIRFQVGGL
>Mature_198_residues
AAVTTDLIRELRERTSAGMMDCKKALEENNADIEKAITWLREKGIAKAAKKAGRETKEGRVVSYIHGNGKIGVLVELNSE
TDFVSKNEDFEALGKEICMQIAAMNPLYLNEESIPAADLEKEKTIMRSQLEAEGKKADQIEKILPGKIKKYISEVCLVNQ
AFFKDDSKTIDDLVKEAIAKFGENITIARFIRFQVGGL

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI291084500, Length=193, Percent_Identity=30.0518134715026, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI291084502, Length=103, Percent_Identity=40.7766990291262, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI171846268, Length=103, Percent_Identity=40.7766990291262, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI291084498, Length=103, Percent_Identity=40.7766990291262, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786366, Length=98, Percent_Identity=51.0204081632653, Blast_Score=99, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19921466, Length=97, Percent_Identity=41.2371134020619, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 22186; Mature: 22055

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVTTDLIRELRERTSAGMMDCKKALEENNADIEKAITWLREKGIAKAAKKAGRETKEG
CCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
RVVSYIHGNGKIGVLVELNSETDFVSKNEDFEALGKEICMQIAAMNPLYLNEESIPAADL
CEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHH
EKEKTIMRSQLEAEGKKADQIEKILPGKIKKYISEVCLVNQAFFKDDSKTIDDLVKEAIA
HHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KFGENITIARFIRFQVGGL
HHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AAVTTDLIRELRERTSAGMMDCKKALEENNADIEKAITWLREKGIAKAAKKAGRETKEG
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
RVVSYIHGNGKIGVLVELNSETDFVSKNEDFEALGKEICMQIAAMNPLYLNEESIPAADL
CEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHH
EKEKTIMRSQLEAEGKKADQIEKILPGKIKKYISEVCLVNQAFFKDDSKTIDDLVKEAIA
HHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KFGENITIARFIRFQVGGL
HHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA