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The map label for this gene is yngJ [H]

Identifier: 45656692

GI number: 45656692

Start: 970275

End: 971450

Strand: Direct

Name: yngJ [H]

Synonym: LIC10801

Alternate gene names: 45656692

Gene position: 970275-971450 (Clockwise)

Preceding gene: 45656689

Following gene: 45656693

Centisome position: 22.68

GC content: 43.71

Gene sequence:

>1176_bases
ATGGATTTTACAATTCCTCAGGAAGTTGAAGAAATCAAAAAAAGAGTTCGGGACTTTGTTGATAATTTTGCGATTCCTGC
TGAAATTCACTATGATTACGATCACGGTAGGATGCCCGAAAAGATCACGGAGGAACTTAGAAAAAAAGTTAAGGATCTCG
GACTTTGGACTCCCCATCTTCCAAAATCGGAAGGAGGACTTGGTCTAGATATGGTCGGAACCGCGATCATCTTTTCTGAG
TTAGGTCGTTCTCCGATCGCTCCTTATCTTTGTAATTGTGATGCTCCCGATGAAGGAAATATGCATCTTCTTCATATCGC
CGCAAACAAAGATCAAAAAGAAAAATTTTATTATCCGCTCGTTCAAGGAAAGATTCGTTCTGCTTTTGCCATGACGGAAC
CTCCTCCCGGTGCGGGAGCTGATCCTCAAACTTTAACTACTAATGCGGTTAAACAAGGAGATGAATACGTGATCAACGGA
CATAAATGGTTTTGCACCGGCGCCAACGGCGCGGATTTTCTGATCGTGATGTCTAAGGTCTCAGATTCTTTTCGAAGAAC
TACTCTATTTTTGGTACCTACAAATACTCCCGGTTATACGATGGTGAGAGAAATTGGTGTGATGGGTTCTCACGGTCCGG
GCGGTCACTGCGAATTAAAGTTTGAAAACGTTCGAGTTTCGGAATCTTCTATTTTGGGAAAAGTAGGCGAGGGATTTAAA
TGGTCTCAAGAACGTCTAGGGCCGGCTCGCCTAACACATTGTATGCGATGGATCGGTCTTGCAAGAAGATCTATGGAAGT
AGCTAGGGAATACGCCCTCAAAAGAGAAGTTTTTGGTCAACGGATTGCAGATCATCAGGGAATTCAATGGATGTTCGCCG
AATCCGCTGTTGAAATCGAGTCCGGTTATATGCTTACTTTGAAAGCGGCTCATACTTTGAGGGCGGGAGAGGACGCGAGA
CAAATCATATCGATGGCAAAATGGCAAGTTTCGGAAACTCTTTGTAAGGTGATCGATCGTGCGATCCAAATTTGTGGTTC
TCATGGCTATGGAAGAGACATGAAATTGGAACTATTTTATAGGGATGCGAGAGCCGCAAGAATTGCGGATGGTCCGAGCG
AAGTTCATAAGATGGTAATCGGAAGAAATCTGATCAGCGGCAAAAGTGATTTTTAA

Upstream 100 bases:

>100_bases
TTCTTACTTGACCTTTTGGATCGTTTAAAATTAAGTTTTCGAACGCATTCTAAAAATATAATTTTCTGTTAAGTGATCAC
TTTCGGTAGAAGGAGAAAAT

Downstream 100 bases:

>100_bases
TATTATAATTCGAGAATATTATGAACGATGCAGAATTAAAAAAGACTCTGGAAAATTATCTTTCCGAAAGACTAAAAGGT
AAAACCGAGATTCATTCTAT

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MDFTIPQEVEEIKKRVRDFVDNFAIPAEIHYDYDHGRMPEKITEELRKKVKDLGLWTPHLPKSEGGLGLDMVGTAIIFSE
LGRSPIAPYLCNCDAPDEGNMHLLHIAANKDQKEKFYYPLVQGKIRSAFAMTEPPPGAGADPQTLTTNAVKQGDEYVING
HKWFCTGANGADFLIVMSKVSDSFRRTTLFLVPTNTPGYTMVREIGVMGSHGPGGHCELKFENVRVSESSILGKVGEGFK
WSQERLGPARLTHCMRWIGLARRSMEVAREYALKREVFGQRIADHQGIQWMFAESAVEIESGYMLTLKAAHTLRAGEDAR
QIISMAKWQVSETLCKVIDRAIQICGSHGYGRDMKLELFYRDARAARIADGPSEVHKMVIGRNLISGKSDF

Sequences:

>Translated_391_residues
MDFTIPQEVEEIKKRVRDFVDNFAIPAEIHYDYDHGRMPEKITEELRKKVKDLGLWTPHLPKSEGGLGLDMVGTAIIFSE
LGRSPIAPYLCNCDAPDEGNMHLLHIAANKDQKEKFYYPLVQGKIRSAFAMTEPPPGAGADPQTLTTNAVKQGDEYVING
HKWFCTGANGADFLIVMSKVSDSFRRTTLFLVPTNTPGYTMVREIGVMGSHGPGGHCELKFENVRVSESSILGKVGEGFK
WSQERLGPARLTHCMRWIGLARRSMEVAREYALKREVFGQRIADHQGIQWMFAESAVEIESGYMLTLKAAHTLRAGEDAR
QIISMAKWQVSETLCKVIDRAIQICGSHGYGRDMKLELFYRDARAARIADGPSEVHKMVIGRNLISGKSDF
>Mature_391_residues
MDFTIPQEVEEIKKRVRDFVDNFAIPAEIHYDYDHGRMPEKITEELRKKVKDLGLWTPHLPKSEGGLGLDMVGTAIIFSE
LGRSPIAPYLCNCDAPDEGNMHLLHIAANKDQKEKFYYPLVQGKIRSAFAMTEPPPGAGADPQTLTTNAVKQGDEYVING
HKWFCTGANGADFLIVMSKVSDSFRRTTLFLVPTNTPGYTMVREIGVMGSHGPGGHCELKFENVRVSESSILGKVGEGFK
WSQERLGPARLTHCMRWIGLARRSMEVAREYALKREVFGQRIADHQGIQWMFAESAVEIESGYMLTLKAAHTLRAGEDAR
QIISMAKWQVSETLCKVIDRAIQICGSHGYGRDMKLELFYRDARAARIADGPSEVHKMVIGRNLISGKSDF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=391, Percent_Identity=36.8286445012788, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI48976061, Length=391, Percent_Identity=36.8286445012788, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI38505218, Length=397, Percent_Identity=35.0125944584383, Blast_Score=234, Evalue=7e-62,
Organism=Homo sapiens, GI4557233, Length=388, Percent_Identity=30.1546391752577, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI4557231, Length=395, Percent_Identity=28.8607594936709, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI187960098, Length=395, Percent_Identity=28.6075949367089, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI4501859, Length=383, Percent_Identity=29.5039164490862, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI7656849, Length=387, Percent_Identity=26.8733850129199, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI226958414, Length=349, Percent_Identity=28.6532951289398, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI226958412, Length=382, Percent_Identity=27.2251308900524, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI21361497, Length=383, Percent_Identity=29.7650130548303, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI4501857, Length=386, Percent_Identity=27.4611398963731, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI76496475, Length=354, Percent_Identity=26.8361581920904, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI4557235, Length=354, Percent_Identity=26.8361581920904, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI4503943, Length=360, Percent_Identity=23.8888888888889, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI7669494, Length=318, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081958, Length=395, Percent_Identity=29.1139240506329, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786223, Length=393, Percent_Identity=27.735368956743, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=387, Percent_Identity=36.9509043927649, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17570075, Length=397, Percent_Identity=33.2493702770781, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17569725, Length=397, Percent_Identity=29.9748110831234, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17534899, Length=397, Percent_Identity=30.9823677581864, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17538396, Length=389, Percent_Identity=30.0771208226221, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17508101, Length=381, Percent_Identity=28.0839895013123, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17506239, Length=345, Percent_Identity=28.695652173913, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17533517, Length=393, Percent_Identity=24.6819338422392, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71990804, Length=283, Percent_Identity=31.8021201413428, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17551932, Length=351, Percent_Identity=26.4957264957265, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17505929, Length=351, Percent_Identity=26.4957264957265, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32563615, Length=248, Percent_Identity=29.4354838709677, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=292, Percent_Identity=27.7397260273973, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=279, Percent_Identity=25.8064516129032, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=25.8333333333333, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17534353, Length=286, Percent_Identity=24.1258741258741, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=216, Percent_Identity=25.462962962963, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=30.6878306878307, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24660351, Length=387, Percent_Identity=29.9741602067183, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI21356377, Length=380, Percent_Identity=31.5789473684211, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24666513, Length=357, Percent_Identity=30.2521008403361, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI21355753, Length=341, Percent_Identity=28.7390029325513, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI281363737, Length=353, Percent_Identity=26.628895184136, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI19920834, Length=401, Percent_Identity=22.9426433915212, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43780; Mature: 43780

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTIPQEVEEIKKRVRDFVDNFAIPAEIHYDYDHGRMPEKITEELRKKVKDLGLWTPHL
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCC
PKSEGGLGLDMVGTAIIFSELGRSPIAPYLCNCDAPDEGNMHLLHIAANKDQKEKFYYPL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCHHHCCHH
VQGKIRSAFAMTEPPPGAGADPQTLTTNAVKQGDEYVINGHKWFCTGANGADFLIVMSKV
HHHHHHHHEECCCCCCCCCCCCCCEEHHHHHCCCCEEEECCEEEEECCCCCCEEEEEHHH
SDSFRRTTLFLVPTNTPGYTMVREIGVMGSHGPGGHCELKFENVRVSESSILGKVGEGFK
CCCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEECCEEECHHHHHHHCCCCCC
WSQERLGPARLTHCMRWIGLARRSMEVAREYALKREVFGQRIADHQGIQWMFAESAVEIE
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEC
SGYMLTLKAAHTLRAGEDARQIISMAKWQVSETLCKVIDRAIQICGSHGYGRDMKLELFY
CCEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
RDARAARIADGPSEVHKMVIGRNLISGKSDF
ECCCHHHCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDFTIPQEVEEIKKRVRDFVDNFAIPAEIHYDYDHGRMPEKITEELRKKVKDLGLWTPHL
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCC
PKSEGGLGLDMVGTAIIFSELGRSPIAPYLCNCDAPDEGNMHLLHIAANKDQKEKFYYPL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCHHHCCHH
VQGKIRSAFAMTEPPPGAGADPQTLTTNAVKQGDEYVINGHKWFCTGANGADFLIVMSKV
HHHHHHHHEECCCCCCCCCCCCCCEEHHHHHCCCCEEEECCEEEEECCCCCCEEEEEHHH
SDSFRRTTLFLVPTNTPGYTMVREIGVMGSHGPGGHCELKFENVRVSESSILGKVGEGFK
CCCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEECCEEECHHHHHHHCCCCCC
WSQERLGPARLTHCMRWIGLARRSMEVAREYALKREVFGQRIADHQGIQWMFAESAVEIE
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEC
SGYMLTLKAAHTLRAGEDARQIISMAKWQVSETLCKVIDRAIQICGSHGYGRDMKLELFY
CCEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
RDARAARIADGPSEVHKMVIGRNLISGKSDF
ECCCHHHCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]