| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
Click here to switch to the map view.
The map label for this gene is leuS
Identifier: 45656415
GI number: 45656415
Start: 621063
End: 623654
Strand: Reverse
Name: leuS
Synonym: LIC10517
Alternate gene names: 45656415
Gene position: 623654-621063 (Counterclockwise)
Preceding gene: 304570513
Following gene: 45656414
Centisome position: 14.58
GC content: 39.27
Gene sequence:
>2592_bases ATGCAATATCCGTTTCAGGAAGTAGAATCTTTTTGGCAAAAATTTTGGGAAGAACACAAAAGTTTTCAAACAAATATCCG GTCTTCTAAACCGAAATTCTACTGCTTGGATATGTTTCCTTATCCTTCCGGGGCCGGATTACACGTAGGTCATCCGGAAG GATATACGGCAACCGACATTCTCTCCAGATTCAAAAGGATGAAAGGTTTTGAAGTTCTGCATCCTATGGGTTGGGATGCG TTTGGACTTCCTGCAGAACGTTATGCAATGCAGACCGGAATTCATCCTGCAATCACCACAAAGGACAATATCGATAACTT TCGTCGTCAAATTCAAATGATCGGCCTTTCCTACGACTGGTCTCGTGAATTGTCTACAACCGATCCAGATTATTATAAAT TTACCCAGTGGATCTTTATCCAACTTTATCAATCTTGGTTTAACCCTGAACTTAAAAAAGCAGAATCTATCAACGAACTC ATCCGTAGATTTTCCAATCAAGGTTCGAACGGCCTGGACTACAGACAATTCAACTCTGAAGAATGGAAAAATTTTTCCCC AGTCGAAAAAGAGAAAATCCTTTCTGATTTCAGATTGGTTTATCAGGCGGAAATTCCAGTCAATTGGTGTGAAGCTCTTG GAACCGTTCTCGCAAACGAAGAAGTGGAAGAATGGGTCGGTAAAGGTTACGAAGTAGTTCGTAAACCGATGCGCCAATAT ATGATGCGAATTACTGCATACGCCGATCGCCTTTTAGAAGATCTTGAGTTAGTCGAGTGGCCACCTTCTACTTTAGAGAT GCAAAAAAACTGGATCGGCAAAAGTGAGGGGCTTGAAATTACATTTCCATTTTTAAAACCTCTGCAAAGCGGTTTAGAAG GAATCCGAATTTTTACCACAAGACCGGATACTATTTTCGGAGTGACTTACATGGTAGTAGCTCCGGAACATCCAATCGTT TCCGAAATTACAACCCCAGAACAAAAACAAAAAGTGGAAGAATACCAAAAAACTTCTTCTTTAAAAAGTGATTTGGATCG GATGGAACTGAATAAAGAAAAAACAGGGGTTTTTACAGGAACTTTTGTTTTTAATCCTGCAGATCCTTCTCAAAAAATTC CGGTTTGGATCAGCGATTATGTGTTATACGGATACGGAACAGGAGCGATCATGGCCGTTCCGGCTCATGATCAAAGAGAC TTTGAGTTTGCAAGAACCTTCGGATTAAAAATTATTCCGGTTATCGAAGGTGAAATTTCAGAAGCAGCCTTTGATTCTAA AACTTCTACGTGTATCAATTCCTCTTCTTCCGAAATTTCGATCAACGGATTGGATTATACTTCCGCTTCTTCTAAAATTA TTTCTTGGGCAGAATCCAAAAAAATCGGTAGGAAAAAAATACAATTTAAACTGAGGGATTGGCTATTTGCAAGACAAAGA TATTGGGGAGAACCAATTCCTTTGGTCCATTATCCTTCTGGAGTCACAAAACCAATTCCAGAATCAGAGCTTCCATTAGT ACTTCCTAATTTAGAAGAATTTAAACCTTCCGGCACGGGAGAGTCTCCCCTCGCACTCGCCAAAGATTGGCTCCAATACA AAGATCCGTCAACGGGAGAAATCGGAACTAGAGAAACGAACACGATGCCTCAATGGGCAGGTTCTTGCTGGTATTATCTG CGTTATATAGATCCTAAAAACGGAAGATTTCTTTGTGATCCAGAGTTAGAAAAGAAATGGATGCCAGTAAATCTTTATGT AGGTGGTTCGGAGCACGCGGTACTTCATCTTCTTTATTCCAGATTTTGGCATAAGTTTTTATTTGATATTGGAGCTGTTT CCACCAAAGAACCGTTCGACAAATTGATCCATCAAGGTTTGATCTTAGGAGAAGACAAACGTAAGATGTCTAAATCTCTC GGAAACGTTGTCAACCCGGATGACGTAATTAAAGAATACGGTGCCGATAGCCTTAGACTCTTTGAGATGTTTATGGGTCC TTTAGAAATGGTTAAACCTTGGAGCACAAGAGGTGTGGAAGGTGTATTCCGTTTTTTGAATAGAATTTGGAGACTCTTTC ATTCTGGTTCCCAAGAATCTTTTCGTTTAGATGATGTCGAACCTACTCCGGAAGAATTGAAAATTCTTCATAAAACAATC CAAAAAGTCAACGAAGACATTCCAAACTTTTCTTTTAACACTGCGATCGCACAACTGATGATTTTTGTGAACGAATTCAC TCCTTCAGATAGAAGACCTAAAAAAGTTTTAGAATCTTTTATTCTTCTTTTGGCCCCGTTTGCTCCTCATATTGCGGAAG AACTTTGGAAACGTTCGGGTAAAATGGAATCCCTTTCCTATGAAAAATTTCCGGAAGCAGATCCTCAGTATCTCGTTGAA TCTGAAATTTTAATCGTGGTTCAAGTGAATGGAAAGTTAAGAGACGAATTCAAAGCCCCTAAAGACGTATCTCAATCAGA TGCTATTTCGATGGCTAAAAATCTAGATAAGATCAAAGGTATCTTGGAAGGGAAAACAATTCGTAAAGAAATTTATGTTC CTGGAAAATTAGTCAATCTTGTGATTGGTTGA
Upstream 100 bases:
>100_bases TCGCACAACTTTACCAATATGATCTTTGTAAATCTTGTTTGAGTAAAACATTTCAAAGATTAATTAAGGTCATAGACTCA GTCAGAAAATAAGGATCGAA
Downstream 100 bases:
>100_bases GGGATTGTAGAATTTTAGACAAAAAATTCTTTTTATTTTTACACATTCATTTTTTCTAAATTAGAATTTTATTGTGTTTT TTCTTTAAAATCGGAATCCG
Product: leucyl-tRNA synthetase
Products: NA
Alternate protein names: Leucine--tRNA ligase; LeuRS [H]
Number of amino acids: Translated: 863; Mature: 863
Protein sequence:
>863_residues MQYPFQEVESFWQKFWEEHKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDILSRFKRMKGFEVLHPMGWDA FGLPAERYAMQTGIHPAITTKDNIDNFRRQIQMIGLSYDWSRELSTTDPDYYKFTQWIFIQLYQSWFNPELKKAESINEL IRRFSNQGSNGLDYRQFNSEEWKNFSPVEKEKILSDFRLVYQAEIPVNWCEALGTVLANEEVEEWVGKGYEVVRKPMRQY MMRITAYADRLLEDLELVEWPPSTLEMQKNWIGKSEGLEITFPFLKPLQSGLEGIRIFTTRPDTIFGVTYMVVAPEHPIV SEITTPEQKQKVEEYQKTSSLKSDLDRMELNKEKTGVFTGTFVFNPADPSQKIPVWISDYVLYGYGTGAIMAVPAHDQRD FEFARTFGLKIIPVIEGEISEAAFDSKTSTCINSSSSEISINGLDYTSASSKIISWAESKKIGRKKIQFKLRDWLFARQR YWGEPIPLVHYPSGVTKPIPESELPLVLPNLEEFKPSGTGESPLALAKDWLQYKDPSTGEIGTRETNTMPQWAGSCWYYL RYIDPKNGRFLCDPELEKKWMPVNLYVGGSEHAVLHLLYSRFWHKFLFDIGAVSTKEPFDKLIHQGLILGEDKRKMSKSL GNVVNPDDVIKEYGADSLRLFEMFMGPLEMVKPWSTRGVEGVFRFLNRIWRLFHSGSQESFRLDDVEPTPEELKILHKTI QKVNEDIPNFSFNTAIAQLMIFVNEFTPSDRRPKKVLESFILLLAPFAPHIAEELWKRSGKMESLSYEKFPEADPQYLVE SEILIVVQVNGKLRDEFKAPKDVSQSDAISMAKNLDKIKGILEGKTIRKEIYVPGKLVNLVIG
Sequences:
>Translated_863_residues MQYPFQEVESFWQKFWEEHKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDILSRFKRMKGFEVLHPMGWDA FGLPAERYAMQTGIHPAITTKDNIDNFRRQIQMIGLSYDWSRELSTTDPDYYKFTQWIFIQLYQSWFNPELKKAESINEL IRRFSNQGSNGLDYRQFNSEEWKNFSPVEKEKILSDFRLVYQAEIPVNWCEALGTVLANEEVEEWVGKGYEVVRKPMRQY MMRITAYADRLLEDLELVEWPPSTLEMQKNWIGKSEGLEITFPFLKPLQSGLEGIRIFTTRPDTIFGVTYMVVAPEHPIV SEITTPEQKQKVEEYQKTSSLKSDLDRMELNKEKTGVFTGTFVFNPADPSQKIPVWISDYVLYGYGTGAIMAVPAHDQRD FEFARTFGLKIIPVIEGEISEAAFDSKTSTCINSSSSEISINGLDYTSASSKIISWAESKKIGRKKIQFKLRDWLFARQR YWGEPIPLVHYPSGVTKPIPESELPLVLPNLEEFKPSGTGESPLALAKDWLQYKDPSTGEIGTRETNTMPQWAGSCWYYL RYIDPKNGRFLCDPELEKKWMPVNLYVGGSEHAVLHLLYSRFWHKFLFDIGAVSTKEPFDKLIHQGLILGEDKRKMSKSL GNVVNPDDVIKEYGADSLRLFEMFMGPLEMVKPWSTRGVEGVFRFLNRIWRLFHSGSQESFRLDDVEPTPEELKILHKTI QKVNEDIPNFSFNTAIAQLMIFVNEFTPSDRRPKKVLESFILLLAPFAPHIAEELWKRSGKMESLSYEKFPEADPQYLVE SEILIVVQVNGKLRDEFKAPKDVSQSDAISMAKNLDKIKGILEGKTIRKEIYVPGKLVNLVIG >Mature_863_residues MQYPFQEVESFWQKFWEEHKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDILSRFKRMKGFEVLHPMGWDA FGLPAERYAMQTGIHPAITTKDNIDNFRRQIQMIGLSYDWSRELSTTDPDYYKFTQWIFIQLYQSWFNPELKKAESINEL IRRFSNQGSNGLDYRQFNSEEWKNFSPVEKEKILSDFRLVYQAEIPVNWCEALGTVLANEEVEEWVGKGYEVVRKPMRQY MMRITAYADRLLEDLELVEWPPSTLEMQKNWIGKSEGLEITFPFLKPLQSGLEGIRIFTTRPDTIFGVTYMVVAPEHPIV SEITTPEQKQKVEEYQKTSSLKSDLDRMELNKEKTGVFTGTFVFNPADPSQKIPVWISDYVLYGYGTGAIMAVPAHDQRD FEFARTFGLKIIPVIEGEISEAAFDSKTSTCINSSSSEISINGLDYTSASSKIISWAESKKIGRKKIQFKLRDWLFARQR YWGEPIPLVHYPSGVTKPIPESELPLVLPNLEEFKPSGTGESPLALAKDWLQYKDPSTGEIGTRETNTMPQWAGSCWYYL RYIDPKNGRFLCDPELEKKWMPVNLYVGGSEHAVLHLLYSRFWHKFLFDIGAVSTKEPFDKLIHQGLILGEDKRKMSKSL GNVVNPDDVIKEYGADSLRLFEMFMGPLEMVKPWSTRGVEGVFRFLNRIWRLFHSGSQESFRLDDVEPTPEELKILHKTI QKVNEDIPNFSFNTAIAQLMIFVNEFTPSDRRPKKVLESFILLLAPFAPHIAEELWKRSGKMESLSYEKFPEADPQYLVE SEILIVVQVNGKLRDEFKAPKDVSQSDAISMAKNLDKIKGILEGKTIRKEIYVPGKLVNLVIG
Specific function: Unknown
COG id: COG0495
COG function: function code J; Leucyl-tRNA synthetase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]
Homologues:
Organism=Homo sapiens, GI7661872, Length=930, Percent_Identity=31.3978494623656, Blast_Score=420, Evalue=1e-117, Organism=Escherichia coli, GI1786861, Length=929, Percent_Identity=36.9214208826695, Blast_Score=574, Evalue=1e-164, Organism=Caenorhabditis elegans, GI71997510, Length=343, Percent_Identity=29.4460641399417, Blast_Score=145, Evalue=7e-35, Organism=Caenorhabditis elegans, GI71997517, Length=330, Percent_Identity=29.0909090909091, Blast_Score=143, Evalue=4e-34, Organism=Caenorhabditis elegans, GI212645227, Length=318, Percent_Identity=29.2452830188679, Blast_Score=114, Evalue=3e-25, Organism=Saccharomyces cerevisiae, GI6323414, Length=906, Percent_Identity=31.8984547461369, Blast_Score=407, Evalue=1e-114, Organism=Drosophila melanogaster, GI21355409, Length=929, Percent_Identity=30.1399354144241, Blast_Score=358, Evalue=8e-99,
Paralogues:
None
Copy number: 800 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001412 - InterPro: IPR002300 - InterPro: IPR002302 - InterPro: IPR014729 - InterPro: IPR009080 - InterPro: IPR013155 - InterPro: IPR009008 [H]
Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]
EC number: =6.1.1.4 [H]
Molecular weight: Translated: 99568; Mature: 99568
Theoretical pI: Translated: 6.07; Mature: 6.07
Prosite motif: PS00178 AA_TRNA_LIGASE_I
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQYPFQEVESFWQKFWEEHKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDI CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEECCCCCCCCHHHH LSRFKRMKGFEVLHPMGWDAFGLPAERYAMQTGIHPAITTKDNIDNFRRQIQMIGLSYDW HHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC SRELSTTDPDYYKFTQWIFIQLYQSWFNPELKKAESINELIRRFSNQGSNGLDYRQFNSE CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCH EWKNFSPVEKEKILSDFRLVYQAEIPVNWCEALGTVLANEEVEEWVGKGYEVVRKPMRQY HCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHH MMRITAYADRLLEDLELVEWPPSTLEMQKNWIGKSEGLEITFPFLKPLQSGLEGIRIFTT HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCEEEEEE RPDTIFGVTYMVVAPEHPIVSEITTPEQKQKVEEYQKTSSLKSDLDRMELNKEKTGVFTG CCCCEEEEEEEEEECCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCEEEE TFVFNPADPSQKIPVWISDYVLYGYGTGAIMAVPAHDQRDFEFARTFGLKIIPVIEGEIS EEEECCCCCCCCCCEEEECEEEEEECCCCEEEECCCCCCCHHHHHHCCCEEEEEECCCHH EAAFDSKTSTCINSSSSEISINGLDYTSASSKIISWAESKKIGRKKIQFKLRDWLFARQR HHHHCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YWGEPIPLVHYPSGVTKPIPESELPLVLPNLEEFKPSGTGESPLALAKDWLQYKDPSTGE HCCCCCCEEECCCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCC IGTRETNTMPQWAGSCWYYLRYIDPKNGRFLCDPELEKKWMPVNLYVGGSEHAVLHLLYS CCCCCCCCCCHHCCCEEEEEEEEECCCCCEEECCCHHCCEEEEEEEECCCHHHHHHHHHH RFWHKFLFDIGAVSTKEPFDKLIHQGLILGEDKRKMSKSLGNVVNPDDVIKEYGADSLRL HHHHHHHHHHCCCCCCHHHHHHHHCCCEECCHHHHHHHHHCCCCCHHHHHHHHCCCHHHH FEMFMGPLEMVKPWSTRGVEGVFRFLNRIWRLFHSGSQESFRLDDVEPTPEELKILHKTI HHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHH QKVNEDIPNFSFNTAIAQLMIFVNEFTPSDRRPKKVLESFILLLAPFAPHIAEELWKRSG HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCC KMESLSYEKFPEADPQYLVESEILIVVQVNGKLRDEFKAPKDVSQSDAISMAKNLDKIKG CCCCCCHHCCCCCCCCCEECCCEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHH ILEGKTIRKEIYVPGKLVNLVIG HHCCCHHHHHEECCHHHHHEECC >Mature Secondary Structure MQYPFQEVESFWQKFWEEHKSFQTNIRSSKPKFYCLDMFPYPSGAGLHVGHPEGYTATDI CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEECCCCCCCCHHHH LSRFKRMKGFEVLHPMGWDAFGLPAERYAMQTGIHPAITTKDNIDNFRRQIQMIGLSYDW HHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC SRELSTTDPDYYKFTQWIFIQLYQSWFNPELKKAESINELIRRFSNQGSNGLDYRQFNSE CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCH EWKNFSPVEKEKILSDFRLVYQAEIPVNWCEALGTVLANEEVEEWVGKGYEVVRKPMRQY HCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHH MMRITAYADRLLEDLELVEWPPSTLEMQKNWIGKSEGLEITFPFLKPLQSGLEGIRIFTT HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCCEEEEEE RPDTIFGVTYMVVAPEHPIVSEITTPEQKQKVEEYQKTSSLKSDLDRMELNKEKTGVFTG CCCCEEEEEEEEEECCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCEEEE TFVFNPADPSQKIPVWISDYVLYGYGTGAIMAVPAHDQRDFEFARTFGLKIIPVIEGEIS EEEECCCCCCCCCCEEEECEEEEEECCCCEEEECCCCCCCHHHHHHCCCEEEEEECCCHH EAAFDSKTSTCINSSSSEISINGLDYTSASSKIISWAESKKIGRKKIQFKLRDWLFARQR HHHHCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YWGEPIPLVHYPSGVTKPIPESELPLVLPNLEEFKPSGTGESPLALAKDWLQYKDPSTGE HCCCCCCEEECCCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCC IGTRETNTMPQWAGSCWYYLRYIDPKNGRFLCDPELEKKWMPVNLYVGGSEHAVLHLLYS CCCCCCCCCCHHCCCEEEEEEEEECCCCCEEECCCHHCCEEEEEEEECCCHHHHHHHHHH RFWHKFLFDIGAVSTKEPFDKLIHQGLILGEDKRKMSKSLGNVVNPDDVIKEYGADSLRL HHHHHHHHHHCCCCCCHHHHHHHHCCCEECCHHHHHHHHHCCCCCHHHHHHHHCCCHHHH FEMFMGPLEMVKPWSTRGVEGVFRFLNRIWRLFHSGSQESFRLDDVEPTPEELKILHKTI HHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHH QKVNEDIPNFSFNTAIAQLMIFVNEFTPSDRRPKKVLESFILLLAPFAPHIAEELWKRSG HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCC KMESLSYEKFPEADPQYLVESEILIVVQVNGKLRDEFKAPKDVSQSDAISMAKNLDKIKG CCCCCCHHCCCCCCCCCEECCCEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHH ILEGKTIRKEIYVPGKLVNLVIG HHCCCHHHHHEECCHHHHHEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA