| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is speE1 [H]
Identifier: 45656336
GI number: 45656336
Start: 497527
End: 499023
Strand: Reverse
Name: speE1 [H]
Synonym: LIC10437
Alternate gene names: 45656336
Gene position: 499023-497527 (Counterclockwise)
Preceding gene: 45656337
Following gene: 45656333
Centisome position: 11.67
GC content: 35.6
Gene sequence:
>1497_bases TTGCAAACGGCGCTTTACATATCAGTCTTAATCATATCTTCTTGTGGCCTCGTTTACGAACTGTTAGCTGGGACAATTGC CTCTTATTTATTAGGAGAAACTGTCACACAATTTTCGCTTATCATTGGAACATATTTGTTTTCAATGGGAGTAGGATCTT GGCTATCAAAATATTTAGAAAAAGATCTGATCCCAAAATTTCTTGAAATAGAACTCGCGATAGGACTCGTAGGGGGATTT AGTTCGGCAATACTTTATTTGAGTTTCGGCCAGATTCGATATTTTCAGATACCGTTATTTTTACTTGTAATCTTAATAGG AATCTTAGTAGGGCTAGAAATTCCAGTATTATTAAGAATATTAAAAAAAGAATTACAGTTCAAGGAACTCGTATCAAGGG TTTTAAGTTTAGATTACGTAGGGGCATTACTCGCATCGATCCTATTTCCAATCTTTTTTGCTCCAAAGCTGGGATTAATG CGAACTGGATTTATATTTGGAATTCTGAATGTGGGAGTAGCGCTCTGGGGGACTTGGGTGCTACCCTTAAGACAAAGCAA AATAATTATACTTCGAGCGCAATCTGTCGTGGTGTTGACCTTATTAATTTTAGGGTTTTCTTATTCGGATTTGATCACAT ATTATAGCGAAGAATCTTTATATACGGATGAGATCATACTATCTAAACAAACCCAATATCAAAGAATTATAGTAACAAGA TGGAAAAATGAAATCCGACTTTTTTTAAACGGACATTTGCAATTCTCGTCGAGAGACGAATATCGCTATCATGAAACATT AGTCCATCCGGCATTACTTGCTCACCCTACTCCGAAAAAGGTATTGGTTCTCGGAGGAGGAGACGGATTAGCAGTTCGTG AAATACTAAAACATAAAAACGTAGAATCCGTAACATTAGTAGATTTGGACTCAGCTATCACAAATCTATTCTCAGAACAT GGGATATTAAAGAAACTAAATGAAGAAAGTTTAAAAAATTCTAAAGTAACAGTGATCAACACGGACGCATTCTTATGGCT GGAAGAATCAGACCAGATATTTGATGTCGTATTGATAGATTTTCCAGATCCGAGTAATTTTTCTTTAGGAAAATTATATA CAACTGCTTTTTTTCATACTTTAAAAAGAAGAATGAACGAAACCTCGGTATTAGAAATACAATCCACATCCCCCCTCTTT GCGCGATCATCTTATTGGTGTATAGAAAGAACAATCGCGTCTCTCGGGTTTTATACTTTACCTTTACACGTATATGTCCC TTCTTTCGGAGAATGGGGCTTTGTACTCGCTGGACAAAGACCAATACAATTCAAAAAAGATTTTCCAAAAGATCTTAAAT TTTTGAATATTCAAGAATTAGAATCTATTCAAACATTTCCACAAGACATGTCTCGCGTTCCAGTTGAAATCAATCGATTG GATAACCAAGCACTTGTGCGTTATTACGATCGAGAATGGAATCGGATTTTAGATTAA
Upstream 100 bases:
>100_bases GAGATAGAGAATGTACCCAAAACTGTACGGGAAAACCCTGGTGTCTACCGCTCTCATTATACAAATTTCATGAGATATTC TGGAGGCAAATAGAAACAAT
Downstream 100 bases:
>100_bases AAACAGTCAAAACAAAACGTAAGATAAGTCAAAAAATTAACTTTCTTCGATTTCTTTTTGAATTTCTTTTGGCAGCCAAT TCCAAACGATGTGATAGTAT
Product: spermidine synthase
Products: NA
Alternate protein names: Putrescine aminopropyltransferase 1; PAPT 1; SPDSY 1 [H]
Number of amino acids: Translated: 498; Mature: 498
Protein sequence:
>498_residues MQTALYISVLIISSCGLVYELLAGTIASYLLGETVTQFSLIIGTYLFSMGVGSWLSKYLEKDLIPKFLEIELAIGLVGGF SSAILYLSFGQIRYFQIPLFLLVILIGILVGLEIPVLLRILKKELQFKELVSRVLSLDYVGALLASILFPIFFAPKLGLM RTGFIFGILNVGVALWGTWVLPLRQSKIIILRAQSVVVLTLLILGFSYSDLITYYSEESLYTDEIILSKQTQYQRIIVTR WKNEIRLFLNGHLQFSSRDEYRYHETLVHPALLAHPTPKKVLVLGGGDGLAVREILKHKNVESVTLVDLDSAITNLFSEH GILKKLNEESLKNSKVTVINTDAFLWLEESDQIFDVVLIDFPDPSNFSLGKLYTTAFFHTLKRRMNETSVLEIQSTSPLF ARSSYWCIERTIASLGFYTLPLHVYVPSFGEWGFVLAGQRPIQFKKDFPKDLKFLNIQELESIQTFPQDMSRVPVEINRL DNQALVRYYDREWNRILD
Sequences:
>Translated_498_residues MQTALYISVLIISSCGLVYELLAGTIASYLLGETVTQFSLIIGTYLFSMGVGSWLSKYLEKDLIPKFLEIELAIGLVGGF SSAILYLSFGQIRYFQIPLFLLVILIGILVGLEIPVLLRILKKELQFKELVSRVLSLDYVGALLASILFPIFFAPKLGLM RTGFIFGILNVGVALWGTWVLPLRQSKIIILRAQSVVVLTLLILGFSYSDLITYYSEESLYTDEIILSKQTQYQRIIVTR WKNEIRLFLNGHLQFSSRDEYRYHETLVHPALLAHPTPKKVLVLGGGDGLAVREILKHKNVESVTLVDLDSAITNLFSEH GILKKLNEESLKNSKVTVINTDAFLWLEESDQIFDVVLIDFPDPSNFSLGKLYTTAFFHTLKRRMNETSVLEIQSTSPLF ARSSYWCIERTIASLGFYTLPLHVYVPSFGEWGFVLAGQRPIQFKKDFPKDLKFLNIQELESIQTFPQDMSRVPVEINRL DNQALVRYYDREWNRILD >Mature_498_residues MQTALYISVLIISSCGLVYELLAGTIASYLLGETVTQFSLIIGTYLFSMGVGSWLSKYLEKDLIPKFLEIELAIGLVGGF SSAILYLSFGQIRYFQIPLFLLVILIGILVGLEIPVLLRILKKELQFKELVSRVLSLDYVGALLASILFPIFFAPKLGLM RTGFIFGILNVGVALWGTWVLPLRQSKIIILRAQSVVVLTLLILGFSYSDLITYYSEESLYTDEIILSKQTQYQRIIVTR WKNEIRLFLNGHLQFSSRDEYRYHETLVHPALLAHPTPKKVLVLGGGDGLAVREILKHKNVESVTLVDLDSAITNLFSEH GILKKLNEESLKNSKVTVINTDAFLWLEESDQIFDVVLIDFPDPSNFSLGKLYTTAFFHTLKRRMNETSVLEIQSTSPLF ARSSYWCIERTIASLGFYTLPLHVYVPSFGEWGFVLAGQRPIQFKKDFPKDLKFLNIQELESIQTFPQDMSRVPVEINRL DNQALVRYYDREWNRILD
Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]
COG id: COG4262
COG function: function code R; Predicted spermidine synthase with an N-terminal membrane domain
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the spermidine/spermine synthase family [H]
Homologues:
Organism=Homo sapiens, GI63253298, Length=253, Percent_Identity=28.0632411067194, Blast_Score=104, Evalue=2e-22, Organism=Escherichia coli, GI1786312, Length=209, Percent_Identity=30.622009569378, Blast_Score=110, Evalue=2e-25, Organism=Caenorhabditis elegans, GI212645616, Length=183, Percent_Identity=31.1475409836066, Blast_Score=85, Evalue=9e-17, Organism=Caenorhabditis elegans, GI25154106, Length=182, Percent_Identity=31.3186813186813, Blast_Score=83, Evalue=4e-16, Organism=Saccharomyces cerevisiae, GI6325326, Length=230, Percent_Identity=31.304347826087, Blast_Score=103, Evalue=5e-23, Organism=Saccharomyces cerevisiae, GI6323175, Length=231, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=6e-21, Organism=Drosophila melanogaster, GI24645443, Length=180, Percent_Identity=30, Blast_Score=94, Evalue=3e-19, Organism=Drosophila melanogaster, GI21355941, Length=126, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001045 [H]
Pfam domain/function: PF01564 Spermine_synth [H]
EC number: =2.5.1.16 [H]
Molecular weight: Translated: 56752; Mature: 56752
Theoretical pI: Translated: 6.96; Mature: 6.96
Prosite motif: PS01330 SPERMIDINE_SYNTHASE_1 ; PS51006 SPERMIDINE_SYNTHASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 1.4 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.0 %Met (Mature Protein) 1.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQTALYISVLIISSCGLVYELLAGTIASYLLGETVTQFSLIIGTYLFSMGVGSWLSKYLE CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH KDLIPKFLEIELAIGLVGGFSSAILYLSFGQIRYFQIPLFLLVILIGILVGLEIPVLLRI HHHCCHHHHHEEEEEECCCHHHHHHHEEECCEEEEHHHHHHHHHHHHHHHHCCHHHHHHH LKKELQFKELVSRVLSLDYVGALLASILFPIFFAPKLGLMRTGFIFGILNVGVALWGTWV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH LPLRQSKIIILRAQSVVVLTLLILGFSYSDLITYYSEESLYTDEIILSKQTQYQRIIVTR EEECCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHEE WKNEIRLFLNGHLQFSSRDEYRYHETLVHPALLAHPTPKKVLVLGGGDGLAVREILKHKN CCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCC VESVTLVDLDSAITNLFSEHGILKKLNEESLKNSKVTVINTDAFLWLEESDQIFDVVLID CCEEEEEEHHHHHHHHHHHCCHHHHHCHHHCCCCCEEEEECCEEEEECCCCCEEEEEEEE FPDPSNFSLGKLYTTAFFHTLKRRMNETSVLEIQSTSPLFARSSYWCIERTIASLGFYTL CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHCCCHHHHHHHHHHCCCEEE PLHVYVPSFGEWGFVLAGQRPIQFKKDFPKDLKFLNIQELESIQTFPQDMSRVPVEINRL EEEEEECCCCCCCEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHCHHHHHCCCEEEECC DNQALVRYYDREWNRILD CCHHHHHHHHHHHHHHCC >Mature Secondary Structure MQTALYISVLIISSCGLVYELLAGTIASYLLGETVTQFSLIIGTYLFSMGVGSWLSKYLE CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH KDLIPKFLEIELAIGLVGGFSSAILYLSFGQIRYFQIPLFLLVILIGILVGLEIPVLLRI HHHCCHHHHHEEEEEECCCHHHHHHHEEECCEEEEHHHHHHHHHHHHHHHHCCHHHHHHH LKKELQFKELVSRVLSLDYVGALLASILFPIFFAPKLGLMRTGFIFGILNVGVALWGTWV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH LPLRQSKIIILRAQSVVVLTLLILGFSYSDLITYYSEESLYTDEIILSKQTQYQRIIVTR EEECCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHEE WKNEIRLFLNGHLQFSSRDEYRYHETLVHPALLAHPTPKKVLVLGGGDGLAVREILKHKN CCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCC VESVTLVDLDSAITNLFSEHGILKKLNEESLKNSKVTVINTDAFLWLEESDQIFDVVLID CCEEEEEEHHHHHHHHHHHCCHHHHHCHHHCCCCCEEEEECCEEEEECCCCCEEEEEEEE FPDPSNFSLGKLYTTAFFHTLKRRMNETSVLEIQSTSPLFARSSYWCIERTIASLGFYTL CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHCCCHHHHHHHHHHCCCEEE PLHVYVPSFGEWGFVLAGQRPIQFKKDFPKDLKFLNIQELESIQTFPQDMSRVPVEINRL EEEEEECCCCCCCEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHCHHHHHCCCEEEECC DNQALVRYYDREWNRILD CCHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12712204 [H]